Patents Assigned to PIOMA INC.
  • Microvesicle histone H2AX as a biomarker for genotoxic stress
    Patent number: 11513125
    Abstract: The invention described herein relates to methods of monitoring genotoxic stress in a test subject, specifically by detecting the expression level of microvesicle-associated H2AX from a biological sample.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 29, 2022
    Assignee: PIOMA, INC.
    Inventor: Alan M. Ezrin
  • 5-ALA for detection of brain tumors
    Patent number: 11307204
    Abstract: The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) and detecting the conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: April 19, 2022
    Assignee: PIOMA, INC.
    Inventor: Alan M. Ezrin
  • 5-ALA FOR DETECTION OF BRAIN TUMORS
    Publication number: 20200124607
    Abstract: The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) and detecting the conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles.
    Type: Application
    Filed: June 7, 2019
    Publication date: April 23, 2020
    Applicant: PIOMA, INC
    Inventor: Alan M. EZRIN
  • 5-ALA for detection of brain tumors
    Patent number: 9493810
    Abstract: The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) and detecting the conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: November 15, 2016
    Assignee: PIOMA, INC.
    Inventor: Alan M. Ezrin
  • 5-ALA FOR DETECTION OF BRAIN TUMORS
    Publication number: 20160326566
    Abstract: The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) and detecting the conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles.
    Type: Application
    Filed: March 15, 2013
    Publication date: November 10, 2016
    Applicant: Pioma Inc.
    Inventor: Alan M. EZRIN
  • 5-ALA FOR DETECTION OF BRAIN TUMORS
    Publication number: 20130330753
    Abstract: The present disclosure relates to methods for detecting brain tumors and assessing the recurrence of such tumors by administering a pharmaceutical composition comprising 5-aminolevulinic acid (5-ALA) and detecting the conversion of 5-ALA to protoporphyrin IX (PPIX) associated with brain-derived microparticles.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 12, 2013
    Applicant: PIOMA INC.
    Inventor: Alan M. EZRIN