Abstract: Thumb carpometacarpal (CMC) joint implants include a trapezium implant defining an articulating surface and a cooperating first metacarpal implant with a base portion of the first metacarpal defining an articulating surface. The first metacarpal base articulating-surface is configured to articulate against the trapezium implant articulating surface.

Abstract: A dual area pressure pulmonary modulator apparatus which provides constant flow, pressure cycled ventilatory support to patients that is additionally equipped with fluid conduits in the valve mechanism and body that allow the clinician or user to manually actuate inhalation by occluding a fluid path emanating from the modulator. Such feature is useful for when the device stops cycling due to physiological changes of the patient, for determining if the patient is cycling the device or if the device is automatically cycling by nature of its setting, coordinating medical procedures with the breathing of the patient, increasing the PEEP beyond the intrinsic design PEEP of the device for a given PIP setting, increasing inspiratory hold time, and providing an easy to use alternative mode of operation for users with less sophistication.

Abstract: A single-use disposable digital tourniquet includes a generally rigid support body comprising first and second spaced apart cuff channels sized and configured to receive a cuff therethrough.

Abstract: Thumb carpometacarpal (CMC) joint implants include a trapezium implant defining an articulating surface and a cooperating first metacarpal implant with a base portion of the first metacarpal defining an articulating surface. The first metacarpal base articulating-surface is configured to articulate against the trapezium implant articulating surface.

Abstract: Methods and devices for treating fractures in or adjacent the wrist and distal forearm employ an intramedullary interlocking fixation rod (i.e, it interlocks the distal and proximal fracture fragments together) to stabilize the skeletal structure in a manner which can inhibit the amount of collapse or loss in skeletal length exhibited by a patient with a distal radius fracture.

Abstract: Medical kits for treating fractures in or adjacent the wrist and distal forearm employ an intramedullary interlocking fixation rod (i.e, it interlocks the distal and proximal fracture fragments together) to stabilize the skeletal structure in a manner which can inhibit the amount of collapse or loss in skeletal length exhibited by a patient with a distal radius fracture.

Abstract: The present invention is directed generally to a first aid treatment package the contents of which can be mixed with available water to create a solution useful for the treatment of wounds, and more specifically, a first aid treatment package the contents of which include a adduct of hydrogen peroxide which when mixed with available water create a hydrogen peroxide solution for the first aid treatment of wounds in remote locations or under circumstances when normal community resources are unavailable.

Abstract: The present invention relates generally to devices and methods for finite control and regulation of patient intrathoracic pressures, and more specifically, to devices and methods that finitely regulates a patient's intrathoracic pressures during repeated cycling events (i.e. respiration) by use of a cross-seal vent valve to form transient pressure windows. The cross-seal vent valve is biased against the pressure necessary to evacuate and/or inflate the lungs of that patient, while a controlled venting of that pressure by at least a partial volume thereof allows for controlled resetting of the baseline pressure to anatomical norms. This enhanced means for regulating intrathoracic pressure are applicable in a number of medically important therapies, including but not limited to, conditioning of pulmonary systems for acclimation to altered environmental conditions, reconditioning of pulmonary system after operating in a diminished state, and application in cardiopulmonary resuscitation procedures.

Abstract: The present invention pertains generally to colorimetric indicia provided by a primary device, and more particularly, to at least one indicator moiety influenced by changing environments wherein the indicator moiety exhibits a rapid initial response and a protracted transient time for visualization by an operator. As compared to heretofore colorimetric indicator technologies, the present invention allows for improved accuracy of data interpretation by direct visual capture of changing environments with shorter duration transients.

Abstract: The present invention is directed generally to a nebulizer for the formation of micro-droplets from liquid medicaments for respiratory patient treatment, and more specifically, to a baffled nebulizer wherein a static baffle used to form an atomized medicament is proximal to a shied which responds to patient respiration force to oscillate from an aerosol flow occluding position to an aerosol flow open position. During inhalation, the shield moves into a first registration format to allow passage of the atomized medicament (nebula) to the patient. During exhalation/non-use, a biasing pressure maintains said shield in a second registration format such that the nebula is retarded from passing to the patient and is coalesced into macro-droplets which return to a supply reservoir for re-atomization.

Abstract: The present invention provides methods of treating microbacterial infections comprising administering to a subject in need thereof, a composition comprising a compound of formula I: wherein: X1, X2 and X3 are selected from the group consisting of oxygen, sulfur, aminoalkyl, alkoxy, aryl, and heteroaryl, unsubstituted or substituted; and R1, R2, R3 and R4 are selected from the group consisting of hydrogen, actinium, silicon, germanium, cyano, alkyl, alkoxy, allyl, alkenyl, alkynyl, alkylaryl, arylalkyl, aminoalkyl, alkylamino, alkene, alkyne, aryl, halide, alkylhalide, alkyloxyalkyl, thioalkyl, alkylthioalkyl, alkylamino, cycloalkyl, heterocyclyl, unsubstituted or substituted; or a pharmaceutically acceptable salt thereof.

Abstract: The present invention pertains generally to a detection means for indicia provided by a primary device, and more particularly, to a detection sensor assembly adapted to measure at least one indicator moiety influenced by changing gaseous environments. A detection sensor assembly performs to collect and respond to changing gaseous environments in real-time, conveying that information to a user of the detection sensor assembly sufficiently quickly and accurately such that the user can respond to the changing gaseous environments in a timely manner. The detection sensor assembly operates using an incident receiver in the form of an indicator sensor. An indicator moiety responsive to particular elements or compounds of interest in a gaseous environment is positioned proximal to the indicator sensor such that changes in the indicator moiety are captured by operation of the indicator sensor.

Abstract: Methods and devices for treating fractures in or adjacent the wrist and distal forearm employ an intramedullary interlocking fixation rod (i.e, it interlocks the distal and proximal fracture fragments together) to stabilize the skeletal structure in a manner which can inhibit the amount of collapse or loss in skeletal length exhibited by a patient with a distal radius fracture.

Abstract: Methods and devices for treating fractures in or adjacent the wrist and distal forearm employ an intramedullary interlocking fixation rod (i.e, it interlocks the distal and proximal fracture fragments together) to stabilize the skeletal structure in a manner which can inhibit the amount of collapse or loss in skeletal length exhibited by a patient with a distal radius fracture.

Abstract: Methods and devices for treating fractures in or adjacent the wrist and distal forearm employ an intramedullary interlocking fixation rod (i.e, it interlocks the distal and proximal fracture fragments together) to stabilize the skeletal structure in a manner which can inhibit the amount of collapse or loss in skeletal length exhibited by a patient with a distal radius fracture.