Patents Assigned to Plant Research International B.V.
  • Publication number: 20120210466
    Abstract: The present invention relates to non-mammalian ?-1,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian ?-1,4-galacto-syltransferase and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian ?-1,4-galactosyltransferases.
    Type: Application
    Filed: April 17, 2008
    Publication date: August 16, 2012
    Applicant: Plant Research International B.V.
    Inventors: Gerard Johan Adolph Rouwendal, Dionisius Elisabeth Antonius Florack, Hendrik Jan Bosch
  • Publication number: 20110067146
    Abstract: The present invention relates to non-mammalian ?-1,4-galactosyltransferases that can be used in their wild-type or in modified forms. The invention further relates to transformed plants and plant cells expressing non-mammalian ?-1,4-galacto-syltransferase and methods to produce glycoproteins with altered and preferably mammalian-type glycosylation. The invention additionally provides nucleic acid molecules and expression vectors of non-mammalian ?-1,4-galactosyltransferases.
    Type: Application
    Filed: April 17, 2008
    Publication date: March 17, 2011
    Applicant: Plant Research International B.V.
    Inventors: Gerard Johan Adolph Rouwendal, Dionisius Elisabeth Antonius Florack, Hendrik Jan Bosch
  • Publication number: 20100227363
    Abstract: The present invention relates to a method to produce proteins reduced in high mannose type glycans in a plant or plant cell by partially inhibiting the expression of the Alg3 gene in said plant or plant cell. Said partial inhibition can be provided for by inserting the Alg3 mutant gene from Arabidopsis as derived from the plant line Salk_040296c or by partially inhibiting the endogenous Alg3 gene by providing the plant or plant cell either with an antisense expression, a sense co-suppressing or with an RNA inhibition genetic construct. Optionally also tissue-specific expression of said inhibiting constructs can yield partial inhibition in a plant.
    Type: Application
    Filed: May 23, 2008
    Publication date: September 9, 2010
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Hendrik Jan Bosch, Alexander Ronald van der Krol, Maurice Gerard Leon Henquet, Dionisius Elisabeth Antonius Florack
  • Publication number: 20100122365
    Abstract: The invention is directed to methods for optimizing glycan processing in organisms (and in particular, plants) so that a glycoprotein having complex type bi-antennary glycans and thus containing galactose residues on both arms and which are devoid of (or reduce in) xylose and fucose can be obtained. The invention is further directed to said glycoprotein obtained and host system comprising said protein.
    Type: Application
    Filed: September 2, 2009
    Publication date: May 13, 2010
    Applicant: Plant Research International B.V.
    Inventors: Hendrikus Antonius Cornelis Bakker, Hendrik Jan Bosch, Dionisius Elisabeth Antonius Florack, Gerard Johan Adolph Rouwendal
  • Patent number: 7601891
    Abstract: The invention is directed to methods for optimizing glycan processing in organisms (and in particular, plants) so that a glycoprotein having complex type bi-antennary glycans and thus 5 containing galactose residues on both arms and which are devoid of (or reduce in) xylose and fucose can be obtained. The invention is further directed to said glycoprotein obtained and host system comprising said protein.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: October 13, 2009
    Assignee: Plant Research International B.V.
    Inventors: Hendrikus Antonius Cornelis Bakker, Hendrik Jan Bosch, Dionisius Elisabeth Antonius Florack, Gerard Johan Adolph Rouwendal
  • Publication number: 20090049568
    Abstract: A method to prevent dehiscence in a plant or to alter plant lignification including providing the plant with a nucleotide protein coding for a GGL protein or a functional equivalent thereof, and growing the plant. Also, the isolated GGL protein or functional equivalents, a nucleic acid encoding the protein and vectors, host cells and plants including the nucleic acid.
    Type: Application
    Filed: July 28, 2005
    Publication date: February 19, 2009
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Andy Pereira
  • Publication number: 20090031455
    Abstract: The present invention provides a novel cytochrome P450 enzyme, as well as vectors and recombinant host cells comprising the gene encoding the enzyme. Provided are recombinant plant with enhanced disease and/or pest resistance, modified favour and/or fragrance and methods for hydroxy lifting terpene substrates.
    Type: Application
    Filed: October 14, 2005
    Publication date: January 29, 2009
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Hendrik Jan Bouwmeester
  • Publication number: 20080286297
    Abstract: The invention relates to a protein complex for the delivery of an antigen to and across mucosal surfaces and the production of said complex in a host cell, such as a plant. Provided is a protein complex comprising at least two, preferably identical, subunits wherein at least one subunit is unaltered and at least one subunit is fused to a first molecule of interest and wherein the protein complex is able to interact with a cell surface receptor via said subunits.
    Type: Application
    Filed: October 8, 2004
    Publication date: November 20, 2008
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Dionisius Elisabeth Antonius Florack, Hendrik Jan Bosch
  • Patent number: 7435876
    Abstract: A method for determining the quality of plant material by making chlorophyll fluorescence images of the material by scanning the material with a beam of electromagnetic radiation so that the chlorophyll present is excitated, and measuring the chlorophyll fluorescence with an imaging detector. From the fluorescence images obtained with a fast and a slow scan, the image of the quantum efficiency of the photosynthetic system of the plant material is calculated. A device for measuring the chlorophyll fluorescence images and a method and devices for sorting and classifying plant material are also described.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: October 14, 2008
    Assignee: Plant Research International B.V.
    Inventors: Hendrik Jalink, Rob Van Der Schoor, Adrianus Henricus Cornelis Maria Schapendonk
  • Publication number: 20080171104
    Abstract: The present invention deals with the production of food products with a health promoting effect, namely immune modulation in general, and lowering and/or stabilizing blood sugar levels. The food products concerned comprise polysaccharides from edible or medicinal mushrooms. These are produced through fermentation instead of conventional cultivation of mushrooms. Fermentation process is preferably done in submerged cultures, especially fed-batch or step-up cultures.
    Type: Application
    Filed: April 7, 2006
    Publication date: July 17, 2008
    Applicant: Plant Research International B.V.
    Inventors: Yang Zhu, Antonius Silvester Maria Sonnenberg, Eibertus Nicolaas Van Loo
  • Patent number: 7214507
    Abstract: The invention provides a method for converting sesquiterpene. The method includes reacting a sesquiterpene substract with a sesquiterpene converting enzyme. The enzyme is from a species or organism containing sesquiterpenes. The sesquiterpene substrate is not naturally present in the species or organism.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: May 8, 2007
    Assignee: Plant Research International B.V.
    Inventors: Hendrik Jan Bouwmeester, Jan-Willem de Kraker, Marloes Schurink, Raoul John Bino, Aede de Groot, Maurice Charles R. Franssen
  • Patent number: 7151170
    Abstract: The present invention provides for a gene obtained during the induction of microspore embryogenisis. The protein encoded by this gene renders plant cells embryongenic, and increases the regenerative capacity of the plant cell. Also disclosed is the regulatory region of this gene and its use for directing the expression of a gene of interest within a suitable host cell.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: December 19, 2006
    Assignees: Plant Research International B.V., Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food Canada
    Inventors: Kim Boutilier, Therese Ouellet, Jan Custers, Jiro Hattori, Brian Miki, Michiel Van Lookeren Campagne
  • Publication number: 20060102851
    Abstract: The present invention relates to a method for determining the quality of plant material by making chlorophyll fluorescence images of said material by scanning the material with a beam of electromagnetic radiation so that the chlorophyll present is excitated, and measuring the chlorophyll fluorescence with an imaging detector. From the fluorescence images obtained with a fast and a slow scan, the image of the quantum efficiency of the photosynthetic system of the plant material is calculated. The invention further relates to a device for measuring the chlorophyll fluorescence images and to a method and devices for sorting and classifying plant material.
    Type: Application
    Filed: October 31, 2003
    Publication date: May 18, 2006
    Applicant: Plant Research International B.V.
    Inventors: Hendrik Jalink, Rob Van Der Schoor, Adrianus Henricus Schapendonk
  • Patent number: 6861578
    Abstract: A method of protecting a plant or part of a plant from insect or nematode infestation is disclosed herein. The method includes the steps of: inserting into the genome of cells or tissue from a plant a sequence coding for equistatin operably linked to a promoter sequence active in the plant to cause expression of the protein at levels which provide an insect or nematode controlling amount of the protein; and regenerating resistant whole plants from the cells or tissue. Also disclosed is a transgenic plant or its sexual progeny which is resistant to attack by one or more insects or nematodes having digestive cysteine proteases. Also disclosed is an expression vehicle that includes a promotor effective to promote expression of a downstream coding sequence in plant cells, the expression vehicle being effective to express in plant cells insect controlling amounts of equistatin.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: March 1, 2005
    Assignee: Plant Research International B.V.
    Inventors: Maarten Anthonie Jongsma, Borut Strukelj, Brigita Lenarcic, Kristina Gruden, Vito Turk, Hendrik J. Bosch, Willem Johannes Stiekema
  • Publication number: 20040161819
    Abstract: The invention relates to the field of genetic engineering of flavor, fragrance and bio-control agent development. More specifically it relates to a process for production of natural flavors, fragrances or bio-control agents by the control of one or more genes implicated in that process. The invention provides an isolated or recombinant nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of flavor, fragrance and/or bio-control agent synthesis when provided with a suitable substrate under appropriate reaction conditions. The invention further provides a nucleic acid or functional fragment thereof encoding a proteinaceous molecule essentially capable of synthesizing at least a monoterpene alcohol linalool when contacted with geranyl diphosphate (GPP) and/or at least a sesquiterpene alcohol nerolidol when contacted with farnesyl diphosphate (FPP) under appropriate reaction conditions.
    Type: Application
    Filed: August 5, 2003
    Publication date: August 19, 2004
    Applicant: PLANT RESEARCH INTERNATIONAL B.V.
    Inventors: Asaph Aharoni, Maarten Anthonie Jongsma, Henricus Andrianus Verhoeven, Hendrik Jan Bouwmeester
  • Patent number: 6664444
    Abstract: A method is disclosed for producing a transgenic plant with a modified inulin producing profile comprising in its genome a combination of one or more expressible 1-SST enzyme encoding genes and one or more expressible 1-FFT enzyme encoding genes, wherein either of these genes or both of them comprise one or more recombinant genes containing one or more 1-SST, respectively 1-FFT, enzyme encoding DNA sequences of plant origin or an expressible homologous sequence thereof. The invention also relates to a method for modifying and controlling the inulin profile of plants and to a method for producing inulin from said transgenic plants. Furthermore, a novel cDNA sequence of a 1-SST enzyme encoding gene of Helianthus tuberosus and a novel cDNA sequence of a 1-FFT enzyme encoding gene of Cichorium intybus are disclosed, novel recombinant DNA constructs and genes derived thereof, as well as novel combinations of expressible 1-SST and 1-FFT enzyme encoding genes.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: December 16, 2003
    Assignees: Tiense Suikerraffinaderij N.V., Plant Research International B.V.
    Inventors: Andries Jurriaan Koops, Robert Sevenier, Arjen Johannes Van Tunen, Lena De Leenheer
  • Patent number: 6407314
    Abstract: The present invention is drawn to an isolated purified DNA sequence from the promoter region of a microspore-specific gene of tobacco. The microspore-specific promoter can play a role in the expression of genes in microspores. The invention also is drawn to chimeric genes suitable for transforming plants comprising the microspore-specific promoter. Further, the invention is also drawn to plants transformed with the chimeric genes.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: June 18, 2002
    Assignee: Plant Research International B.V.
    Inventors: Margryt Teatske Oldenhof, George Joseph Wullems, Jan Antonius Maria Schrauwen, Michiel Maurits Van Lookeren Campagne, Johannes Bernardus Maria Custers, Johannes Jacobus Maria Dons
  • Patent number: PP18000
    Abstract: A new and distinct cultivar of Strawberry plant named ‘Sonata’, characterized by its compact growth habit; large and uniformly conical fruits; firm fruits; glossy light red-colored fruits; and pleasant fruit aroma and taste.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: September 11, 2007
    Assignee: Plant Research International B.V.
    Inventor: Egbertus Joseph Meulenbroek
  • Patent number: PP18079
    Abstract: A new and distinct cultivar of Strawberry plant named ‘Figaro’, characterized by its vigorous growth habit; large and uniformly rounded fruits; very firm fruits; glossy light red-colored fruits; and pleasant fruit aroma and taste.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: September 25, 2007
    Assignee: Plant Research International, B.V.
    Inventor: Egbertus Joseph Meulenbroek