Patents Assigned to Plantorgan-Werk Heinrich G. F. Christensen, KG
  • Hirudin-PA and its derivatives, process for manufacturing these and the use of these substances
    Patent number: 4767742
    Abstract: The present invention relates to a new content substance found in leeches (Hirudo medicinalis), the derivatives of this abbreviated at the N-terminus and the C-terminus, and the desulfated derivatives therefrom as well as a process for the production of these compounds, and their use. These compounds possess thrombin-inhibiting properties and can be used to inhibit clotting in human and animals, for blood conservation, or as reagents for the analytical determination of thrombin.
    Type: Grant
    Filed: August 6, 1986
    Date of Patent: August 30, 1988
    Assignee: Plantorgan-Werk Heinrich G. F. Christensen, KG
    Inventors: Johannes Dodt, Ursula Seemuller, Hans Fritz, Ernst Fink