Patents Assigned to Polyganics IP B.V.
  • Tissue-adhesive polymers
    Patent number: 11801325
    Abstract: The invention is directed to a multi-arm tissue-adhesive polymer wherein at least six or more arms each comprise a reactive functional group that can form a urethane or a urea bond with an amine group present in tissue, as well as to the use thereof for sealing or closing of tissue and use in a medical treatment of a human or animal body. In a further aspect, the invention is directed to a method for the preparation of said multi-arm tissue-adhesive polymer.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: October 31, 2023
    Assignee: Polyganics IP B.V.
    Inventors: Martin Franke Tooren, Justin Van Der Veen, Dirk Erik Muller
  • Tissue-adhesive material
    Patent number: 11779679
    Abstract: The invention is directed to a tissue-adhesive polymer blend comprising a bioresorbable carrier polymer and a bioresorbable synthetic tissue-reactive polymer as well as to a tissue-adhesive device for sealing dura mater comprising said tissue-adhesive polymer blend.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: October 10, 2023
    Assignee: Polyganics IP B.V.
    Inventors: Leendert Willem Schwab, Konstantin Igorovitch Denisov, Martin Franke Tooren, Theodorus Petrus Cornelis Van Doormaal
  • Biomedical polyurethanes
    Patent number: 11633517
    Abstract: The invention is directed to biomedical polyurethanes. The invention is particularly directed to biomedical polyurethanes with improved biodegradability and to an improved preparation of the biomedical polyurethanes. In particular the present invention provides a biomedical polyurethane having the formula (A-B-C-B)n, wherein A denotes a polyol, B denotes a diisocyanate moiety, C denotes a diol component and n denotes the number of recurring units, and wherein the B-C-B segment is bioresorbable.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: April 25, 2023
    Assignee: Polyganics IP B.V.
    Inventors: Martin Franke Tooren, Dirk Erik Muller, Konstantin Igorovitch Denisov
  • Tissue-adhesive sealant device
    Patent number: 11160900
    Abstract: The invention is directed to a biodegradable tissue-adhesive device for sealing tissue, said device comprising a tissue-adhesive layer which comprises a blend of a tissue-reactive polymer and a biodegradable carrier polyurethane according to the formula of A-B-C-Bn, wherein A denotes a polyol, B denotes a diisocyanate moiety, C denotes a diol component and n denotes the number of recurring units, and wherein the B-C-B segment is bioresorbable.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: November 2, 2021
    Assignee: Polyganics IP B.V.
    Inventors: Martin Franke Tooren, Justin Van Der Veen, Dirk Erik Muller, Don Theo Hertsig, Harmen Hendrikus de Vries, Romke Stephan Rudolf Ribbels
  • Nerve cap and production thereof
    Patent number: 10850004
    Abstract: The invention is directed to a nerve cap for covering a nerve stump, comprising a tubular body with a closed end and an open end and essentially consisting of biodegradable polymeric material to prevent or treat symptoms caused by neuroma. The polymeric material preferably comprises a poly(DL-lactide-co-?-caprolactone) copolymer obtained by the copolymerizaton of DL-lactide and ?-caprolactone, which copolymer has a lactide content of 51-75 mol %.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: December 1, 2020
    Assignee: Polyganics IP B.V.
    Inventors: Pieter van den Berg, Hans Wicher Kuijper, Leendert Willem Schwab, Mariëtta Johanna Olga Elizabeth Bertleff, Harmen Hendrikus de Vries
  • Tissue-Adhesive Biomedical Materials
    Publication number: 20200254137
    Abstract: The invention is directed to a biodegradable tissue-adhesive polyurethane polymer comprising at least one amorphous segment and at least one polyurethane segment, wherein at least one of said polyurethane segment comprises a tissue-reactive functional group. A further aspect of the invention is directed to biodegradable tissue-adhesive medical devices, based on the polyurethane polymer, having the structure of a sheet, foam, stent, tube or gel. The polyurethane polymer and the device can be used in medical application.
    Type: Application
    Filed: March 31, 2017
    Publication date: August 13, 2020
    Applicants: Polyganics IP B.V., Polyganics IP B.V.
    Inventors: Martin Franke Tooren, Dirk Erik Muller, Justin Van Der Veen