Abstract: A deflection-type refractometer with extended measurement range having a light source generating a beam of light; a measuring cell with a sample chamber receiving a sample liquid; an optical sensor mounted on a movable platform for detecting the deflected beam of light; a driving unit configured to move the platform; a distance measurement unit for monitoring the displacement of the platform; a control unit configured to calculate the deflection of the beam of light based on the displacement of the platform and an output signal of the optical sensor to obtain a refractive index measure of the sample liquid using the calculated deflection.

Abstract: The invention relates to a process for separating and/or purifying organic compounds susceptible to crystallization by means of crystallizing and dissolving comprising the following steps: a) depositing the composition in the head of a separation and/or crystallization column; b) crystallizing by means of a cooling gradient; c) pumping the solvent at optimal flow rate Fc; d) entraining the components while they are not crystallized to the end of the column; e) stopping the pumping of the solvent until reaching the lowest temperature of the interval established by the cooling gradient; f) heating the column; g) beginning new pumping by means of applying flow rate Fe; h) collecting the eluates; and i) detecting by means of detectors.

Abstract: The invention relates to a process for separating and/or purifying organic compounds susceptible to crystallization by means of crystallizing and dissolving comprising the following steps: a) depositing the composition in the head of a separation and/or crystallization column; b) crystallizing by means of a cooling gradient; c) pumping the solvent at optimal flow rate Fc; d) entraining the components while they are not crystallized to the end of the column; e) stopping the pumping of the solvent until reaching the lowest temperature of the interval established by the cooling gradient; f) heating the column; g) beginning new pumping by means of applying flow rate Fe; h) collecting the eluates; and i) detecting by means of detectors.