Patents Assigned to Polyphor AG/Ltd.
  • Template-fixed peptidomimetics as medicaments against HIV and cancer
    Patent number: 7838496
    Abstract: Template-fixed ?-hairpin peptidomimetics of the General Formula (I); wherein Z1 and Z2 are template-fixed chains of 4 and 6 or 5 and 7 ?-amino acid residues and salts thereof. They have CXCR4-antagonizing properties and can be used as medicaments. These ?-sheet peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: November 23, 2010
    Assignees: Polyphor AG/Ltd., Universität Zürich
    Inventors: Jürg Zumbrunn, Steven J. Demarco, Sergio Lociuro, Jan Wim Vrijbloed, Frank Gombert, Reshmi Mukherjee, Kerstin Moehle, Daniel Obrecht, Barbara Romagnoli, John Anthony Robinson