Patents Assigned to PONDICHERRY BIOTECH PRIVATE LIMITED (PBPL)
  • Obligate heterodimer variants of foki cleavage domain
    Patent number: 9057057
    Abstract: Disclosed are methods of making and using engineered FokI cleavage domain variants. Also disclosed are methods, compositions and fusion proteins containing obligate heterodimers of engineered FokI cleavage domain variants and DNA binding domains, such as zinc finger protein (ZFP) domains and transcription activator-like effector (TALE) domains.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: June 16, 2015
    Assignees: THE JOHNS HOPKINS UNIVERSITY, PONDICHERRY BIOTECH PRIVATE LIMITED (PBPL)
    Inventors: Srinivasan Chandrasegaran, Sivaprakash Ramalingam, Karthikeyan Kandavelou