Patents Assigned to Possis Medical, Inc.
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Patent number: 6676627Abstract: Cross stream thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives cross stream streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.Type: GrantFiled: October 13, 1999Date of Patent: January 13, 2004Assignee: Possis Medical, Inc.Inventors: Michael J. Bonnette, John Edward Morris, Steven E. Wiesel, John B. Bridgeman, Debra M. Kozak, Rosemary C. Beaupre, Mark L. Jenson, Cindy M. Setum, Robert C. Dutcher
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Publication number: 20030088263Abstract: A guidewire occlusion system for use in vascular procedures includes a repeatably inflatable gas-filled occlusive device proximate a distal end of a tubular guidewire assembly having an extended sealable section proximate a proximal end. A gas inflation/evacuation system is removably connectable to the proximal end of the guidewire assembly and includes an evacuation system to evacuate air from the guidewire and an inflation system for introducing a gas under pressure into the guidewire to inflate the occlusive balloon a plurality of times. A sealing system is also removably connectable to the proximal end of the guidewire assembly and selectively seals the extended sealable section at one of a plurality of separate locations along the extended sealable section to form an airtight seal of the tubular guidewire.Type: ApplicationFiled: November 6, 2001Publication date: May 8, 2003Applicant: Possis Medical, Inc.Inventors: Michael J. Bonnette, Eric J. Thor
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Publication number: 20030088262Abstract: A tubular guidewire assembly having an occlusive device and an extended crimpable section proximate a proximal end that is adapted to connect to a gas inflation/evacuation system. The extended crimpable section can be selectively sealed at one of a plurality of separate locations to form an airtight seal of the tubular guidewire assembly. Each time a deflation of the occlusive device is desired to reestablish blood flow to a vessel downstream of the occlusive device, the extended crimpable section preferably is cut distal to the location of the last seal to quickly deflate the occlusive device.Type: ApplicationFiled: November 6, 2001Publication date: May 8, 2003Applicant: Possis Medical,IncInventors: Michael J. Bonnette, Eric J. Thor, Mark L. Jenson, Rick C. Kravik, Hieu V. Le
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Patent number: 6558366Abstract: A method of and apparatus for removing a thrombus deposit from the cardiovascular system of a patient without the need to surgically access the location of the thrombus deposit via a cut-down or other surgical procedure. A catheter is inserted percutaneously into the patient at a convenient location either directly or over a previously positioned guide wire. The distal end of the catheter is advanced under fluoroscopy to the site of the thrombus deposit. A balloon is inflated to stabilize the position of the distal end of the catheter within the center of the vessel lumen. A flexible metal tube conveys an extremely high pressure stream of sterile saline solution to at least one jet at the distal end of the catheter. At least one jet positions the thrombus deposit for emulsification by at least one other jet. By directing the jets toward the orifice of the large evacuation lumen of the catheter, a stagnation pressure is induced which propels the emulsion proximally for disposal.Type: GrantFiled: December 5, 1994Date of Patent: May 6, 2003Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6544209Abstract: A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness.Type: GrantFiled: December 8, 1994Date of Patent: April 8, 2003Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6471683Abstract: A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A catheter is inserted percutaneously into the patient at a convenient location either directly or over a previously positioned guidewire or inside a guide catheter. The distal end of the catheter is advanced under fluoroscopy to the site of the thrombus or tissue deposit. Alternatively, the catheter may be positioned at the desired location by surgical procedure. An elastic balloon may be inflated to stabilize the position of the distal end of the catheter within the center of the vessel lumen. A dilatation balloon may be inflated perioperatively to dilate the underlying vessel or tubule lesion.Type: GrantFiled: December 8, 1994Date of Patent: October 29, 2002Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6355027Abstract: Flexible microcatheter having regions of different flexibility integrally and strategically placed along and about the length of a one-piece composite catheter tube. Distally the flexible microcatheter exhibits pronounced flexibility with respect to locations or regions of flexibility located proximally for navigation along tortuous vascular paths. Different regions of flexibility are formed by applying resins of different Shore hardness readings either singularly or in combination along and about a braid which overlies an inner resin layer. The encapsulated braid provides resistance to kinking and bending of the flexible microcatheter as well as providing for torque transmission and pushability along the length of the flexible microcatheter.Type: GrantFiled: June 9, 1999Date of Patent: March 12, 2002Assignee: Possis Medical, Inc.Inventors: Hieu V. Le, John Edward Morris, Cindy M. Setum, Robert G. Dutcher
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Publication number: 20010051811Abstract: Crossflow thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives crossflow streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.Type: ApplicationFiled: August 16, 2001Publication date: December 13, 2001Applicant: Possis Medical, Inc.Inventors: Michael J. Bonnette, John Edward Morris, Steven E. Wiesel, John B. Bridgeman, Debra M. Kozak, Rosemary C. Beaupre, Mark L. Jenson, Cindy M. Setum, Robert C. Dutcher
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Publication number: 20010051785Abstract: Crossflow thrombectomy catheter and system for fragmentation and removal of thrombus or other material from blood vessels or other body cavities. High velocity saline jets emitted from a toroidal loop jet emanator or other jet emanator in a catheter distal end entrain fluid through inflow orifices, and with flow resistances create a back-pressure which drives crossflow streams through outflow orifices in a radial direction and thence radially and circumferentially to apply normal and drag forces on thrombotic deposits or lesions in the blood vessel or other body cavity, thereby breaking apart and transporting thrombus particles to be entrained through the inflow orifices, whereupon the high velocity jets macerate the thrombus particles which then transit an exhaust lumen or recirculate again via the outflow orifices.Type: ApplicationFiled: August 16, 2001Publication date: December 13, 2001Applicant: Possis Medical, Inc.Inventors: Michael J. Bonnette, John Edward Morris, Steven E. Wiesel, John B. Bridgeman, Debra M. Kozak, Rosemary C. Beaupre, Mark L. Jenson, Cindy M. Setum, Robert C. Dutcher
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Patent number: 6258061Abstract: A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness.Type: GrantFiled: December 8, 1994Date of Patent: July 10, 2001Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6224570Abstract: A rheolytic thrombectomy catheter and method of using same to remove thrombus from a body vessel or other body cavity. Several embodiments are disclosed. All embodiments include an outer catheter having a lumen and an inner high pressure tube of a size to enable it to be passed through the lumen of the catheter. The distal end of the inner high pressure tube extends beyond the distal end of the catheter and carries a jet cap for directing one or more jets of saline proximally toward the distal end of the catheter. In some embodiments, the catheter has a distally located inwardly directed stationary stop and the inner high pressure tube includes a distally located outwardly directed transitional stop for engaging the inwardly directed stationary stop to thereby position the jet cap at a defined distance from the distal end of the catheter.Type: GrantFiled: November 9, 1998Date of Patent: May 1, 2001Assignee: Possis Medical, Inc.Inventors: Hieu V. Le, Michael J. Bonnette, John Edward Morris, Steven E. Wiesel, Debra M. Kozak, Cindy M. Setum, Robert G. Dutcher
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Patent number: 6135977Abstract: A technique for treatment of plaque deposits on the arterial wall of a patient. The technique employs a high pressure jet of sterile saline solution directed at the plaque deposit. The high pressure jet is located at the distal end of a guide wire or catheter which is advanced through the vascular system to the site of the plaque deposit. Optional removal of the debris is via an evacuation lumen within the catheter. This particular technique directs the high pressure jet of fluid distal to the distal tip of the guide wire or catheter. This permits treatment of arteries, which are totally occluded, because the device need not transit the lesion to be effective. Some applications will use the high pressure jet of fluid to open a sufficient passage within the occlusion to permit further dilatation using a balloon integral to or passed over the device. An ultrasonic transducer array located adjacent the high pressure jet permits the attending physician to monitor the procedure.Type: GrantFiled: January 25, 1995Date of Patent: October 24, 2000Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6129697Abstract: A device for removing a thrombus or other tissue deposit from the cardiovascular system, or from a natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one orifice at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen.Type: GrantFiled: December 8, 1994Date of Patent: October 10, 2000Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 6096001Abstract: A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness.Type: GrantFiled: December 8, 1994Date of Patent: August 1, 2000Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 5989210Abstract: A surgical device and method for removal of tissue, such as thrombus, from a vessel in the body. The device has a first tube with a distal open end and an inward directed stop and a second tube with an outward directed stop for engaging the inward directed stop and thereby regulating the relationship between a retrograde jet and the distal open end. Thrombus is dislodged, entrained, and broken into pieces which are evacuated through the first tube.Type: GrantFiled: February 6, 1998Date of Patent: November 23, 1999Assignee: Possis Medical, Inc.Inventors: John Edward Morris, Cindy M. Setum, William J. Drasler, Hieu V. Le, Robert G. Dutcher
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Patent number: 5989271Abstract: A rheolytic thrombectomy catheter and method of using same to remove thrombus from a body vessel or other body cavity. The rheolytic thrombectomy catheter has a first tube with a distal open end and a second tube aligned within the first tube and having a flexible tip assembly. A tapered and flexible tip follows a guidewire within and along tortuous and difficult vasculature paths to the site of thrombus. The flexible tip assembly, includes a soft flexible tip and also includes a hard plastic shell offering structural integrity and rigid alignment between a toroidal loop and an inner body to prevent lever arm distortion and to maintain spray gap alignment for saline jet flow emanating from the toroidal loop. Saline jets dislodge, entrain, and break thrombus into pieces which are evacuated through the dual lumen tube.Type: GrantFiled: November 9, 1998Date of Patent: November 23, 1999Assignee: Possis Medical, Inc.Inventors: Michael J. Bonnette, John Edward Morris, Steven E. Wiesel, Cindy M. Setum, Robert C. Dutcher, William J. Drasler
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Patent number: 5866217Abstract: A silicone composite vascular graft especially well suited as an arteriovenous (A-V) graft fistula for dialysis application. The graft has the ability to seal around needle puncture holes without externally applied pressure, excellent anti-kink, anti-crush and strength properties, and a smooth non-porous inner surface which reduces thrombus deposition and enhances the graft wall compliance or elasticity.Type: GrantFiled: November 4, 1991Date of Patent: February 2, 1999Assignee: Possis Medical, Inc.Inventors: Mark D. Stenoien, William J. Drasler, Robert J. Scott, Mark L. Jenson
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Patent number: 5840240Abstract: A silicone/DACRON polyester composite vascular graft especially well suited as an arteriovenous (A-V) graft fistula for dialysis application. The graft has the ability to seal around needle puncture holes without externally applied pressure, excellent anti-kink, anti-crush and strength properties, and a smooth non-porous inner surface which reduces thrombus deposition and enhances the graft wall compliance or elasticity.Type: GrantFiled: November 3, 1995Date of Patent: November 24, 1998Assignee: Possis Medical, Inc.Inventors: Mark D. Stenoien, William J. Drasler, Robert J. Scott, Mark L. Jenson
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Patent number: 5785675Abstract: A method of and apparatus for removing a thrombus deposit from the cardiovascular system of a patient without the need to surgically access the location of the thrombus deposit via a cut-down or other surgical procedure. A catheter is inserted percutaneously into the patient at a convenient location either directly or over a previously positioned guide wire. The distal end of the catheter is advanced under fluoroscopy to the site of the thrombus deposit. A balloon is inflated to stabilize the position of the distal end of the catheter within the center of the vessel lumen. A flexible metal tube conveys an extremely high pressure stream of sterile saline solution to at least one jet at the distal end of the catheter. At least one jet positions the thrombus deposit for emulsification by at least one other jet. By directing the jets toward the orifice of the large evacuation lumen of the catheter, a stagnation pressure is induced which propels the emulsion proximally for disposal.Type: GrantFiled: December 5, 1994Date of Patent: July 28, 1998Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios
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Patent number: 5496267Abstract: A technique for ablation and removal of plaque deposits from the arterial, venous, vascular graft or other tissue wall of a patient. Ablation is accomplished by directing a high pressure jet of sterile saline solution at the plaque deposit. The high pressure jet is located at the distal end of a catheter which is advanced through the vascular system to the site of the plaque deposit. Removal of the debris is via an evacuation lumen within the catheter.The arterial wall is protected from damage by the catheter design which directs the high pressure jet towards a portion of the distal end of the catheter which serves as a target. The distal end of the catheter is placed such that the plaque or other deposit to be ablated is positioned between the high pressure jet and the target.An optional ultrasonic transducer array located adjacent the high pressure jet and the evacuation lumen permits the attending physician to monitor the procedure.Type: GrantFiled: November 8, 1990Date of Patent: March 5, 1996Assignee: Possis Medical, Inc.Inventors: William J. Drasler, Robert G. Dutcher, Mark L. Jenson, Joseph M. Thielen, Emmanuil I. Protonotarios