Patents Assigned to Precision Neuroscience Corporation
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Publication number: 20240131335Abstract: A system for performing spinal cord stimulation on a subject is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be minimally invasively inserted to a target stimulation site within the nervous tissue, includes stimulation electrodes. The processor is configured to receive more recorded signals from the recording arrays at the target recording site, determine an electrophysiological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the determined electrophysiological state in order to affect the electrophysiological state.Type: ApplicationFiled: October 19, 2023Publication date: April 25, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Craig H. MERMEL, Daniel TRIETSCH, Mark HETTICK, Elton HO, Kazutaka TAKAHASHI
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Publication number: 20240130682Abstract: A medical device system that can include a medical device configured to sense data associated with the subject or receive control input, an external device communicably coupled to the medical device, a storage medium communicably coupled to the external device, and one or more communications interfaces between the medical device, the external device, and the storage medium or components thereof, wherein the one or more communications interfaces comprise an encryption protocol.Type: ApplicationFiled: October 19, 2023Publication date: April 25, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Mark HETTICK, Craig H. MERMEL, Manuel MONGE, Mark MURPHY, Daniel TRIETSCH
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Publication number: 20240131342Abstract: A system for performing deep brain stimulation on a brain of a patient is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be inserted to a target stimulation site within the deep brain, includes at least one stimulation electrode. The processor is configured to receive one or more recorded signals from the recording arrays at the target recording site, determine a neurological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the neurological state in order to electrically stimulate the brain.Type: ApplicationFiled: October 19, 2023Publication date: April 25, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Craig H. MERMEL, Mark HETTICK, Elton HO
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Publication number: 20240134453Abstract: A systems and methods for calibrating a neural device using transfer learning techniques. The methods can include aggregating calibration data across a user population to define a global dataset, identifying similar data segments across the global dataset to define a task-independent training dataset, training a feature extraction model based on the task-independent training dataset to define a trained, task-independent feature extraction model, receiving the calibration data from a user calibrating the neural device, and calibrating a user-specific feature extraction model using the trained, task-independent feature extraction model and the calibration data.Type: ApplicationFiled: October 23, 2023Publication date: April 25, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Craig H. MERMEL, Daniel TRIETSCH, Elton HO, Kazutaka TAKAHASHI
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Publication number: 20240137348Abstract: A neural device system that can include a neural device configured to sense data associated with the subject or receive control input, an external device communicably coupled to the neural device, a storage medium communicable coupled to the external device, and one or more communications interfaces between the neural device, the external device, and the storage medium or components thereof, wherein the one or more communications interfaces comprise an encryption protocol.Type: ApplicationFiled: October 19, 2023Publication date: April 25, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Mark HETTICK, Craig H. MERMEL, Manuel MONGE, Mark MURPHY, Daniel TRIETSCH
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Publication number: 20240115178Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.Type: ApplicationFiled: October 17, 2023Publication date: April 11, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Demetrios Philip Papageorgiou, Mark Hettick, Adam Poole, Elton Ho
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Publication number: 20230380766Abstract: The present disclosure is directed to systems and methods for endovascular electroencephalography (EEG) and electrocorticography (ECoG) systems. In some embodiments, the disclosed systems include electrode arrays that are configured to record and/or stimulate brain tissue via placement within blood vessels of the brain. Venous and arterial EEG and ECoG electrodes, ambulatory EEG and ECoG systems, and transcutaneous access and signal control systems for general and ambulatory endovascular electroencephalography (EEG) and electrocorticography (ECoG), as well as endovascular neural stimulating electrodes are discussed.Type: ApplicationFiled: August 7, 2023Publication date: November 30, 2023Applicant: PRECISION NEUROSCIENCE CORPORATIONInventor: Benjamin I. RAPOPORT
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Publication number: 20230285742Abstract: Disclosed are systems and methods for circuit- and system-level techniques and approaches for data encryption in scalable, high-bandwidth, bidirectional neural interfaces. In some embodiments, the disclosed systems and methods may be configured to encrypt neural data as close as possible to the data source, and before the data is transmitted out of the body. In some embodiments, the disclosed systems and methods may utilize hardware-based approaches, including those involving modified analog-to-digital converters, and symmetric cryptographic algorithms.Type: ApplicationFiled: March 8, 2023Publication date: September 14, 2023Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Manuel MONGE
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Publication number: 20230210427Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.Type: ApplicationFiled: December 30, 2022Publication date: July 6, 2023Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin Issac RAPOPORT, Demetrios Philip PAPAGEORGIOU, Mark HETTICK, Adam POOLE, Elton HO
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Publication number: 20230201574Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.Type: ApplicationFiled: November 7, 2022Publication date: June 29, 2023Applicant: Precision Neuroscience CorporationInventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen
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Patent number: 11491323Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.Type: GrantFiled: January 27, 2022Date of Patent: November 8, 2022Assignee: Precision Neuroscience CorporationInventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen
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Patent number: 11406814Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.Type: GrantFiled: May 10, 2019Date of Patent: August 9, 2022Assignee: Precision Neuroscience CorporationInventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen
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Publication number: 20220167924Abstract: The present disclosure is directed to systems and methods for endovascular electroencephalography (EEG) and electrocorticography (ECoG) systems. In some embodiments, the disclosed systems include electrode arrays that are configured to record and/or stimulate brain tissue via placement within blood vessels of the brain. Venous and arterial EEG and ECoG electrodes, ambulatory EEG and ECoG systems, and transcutaneous access and signal control systems for general and ambulatory endovascular electroencephalography (EEG) and electrocorticography (ECoG), as well as endovascular neural stimulating electrodes are discussed.Type: ApplicationFiled: February 15, 2022Publication date: June 2, 2022Applicant: PRECISION NEUROSCIENCES CORPORATIONInventor: Benjamin I. Rapoport
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Publication number: 20220167925Abstract: Described herein are systems and methods for deploying and recording electrophysiologic signals from electrode arrays located within the dura mater of the brain. The dura matter includes layers of connective tissue, or membrane, that surround the brain and spinal cord. The present disclosure relates to an endovascular electrode system deployed within the blood vessels located between layers of the dura mater, including, for example, the middle meningeal artery and its branches.Type: ApplicationFiled: February 15, 2022Publication date: June 2, 2022Applicant: PRECISION NEUROSCIENCES CORPORATIONInventor: Benjamin I. RAPOPORT
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Publication number: 20220143396Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.Type: ApplicationFiled: January 27, 2022Publication date: May 12, 2022Applicant: Precision Neuroscience CorporationInventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen