Abstract: In an aspect, the present disclosure provides a method for printing an object, comprising: directing at least one energy beam from an energy source into a media chamber comprising at least one polymeric precursor to generate said object at a fine resolution within a certain time period.
Type:
Grant
Filed:
June 22, 2021
Date of Patent:
March 5, 2024
Assignee:
Prellis Biologics, Inc.
Inventors:
Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
Type:
Grant
Filed:
October 30, 2019
Date of Patent:
September 26, 2023
Assignee:
PRELLIS BIOLOGICS, INC
Inventors:
Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
Abstract: Provided herein are methods and systems for forming a three-dimensional object corresponding to an organ or organoid. A method for forming a three-dimensional object corresponding to an organ or organoid may comprise generating a plurality of discrete focal points patterned as a 3D projection corresponding to the organ or organoid in a medium comprising one or more precursors of a polymer, to form at least a portion of the 3D object corresponding to the organ or organoid.
Type:
Grant
Filed:
October 30, 2019
Date of Patent:
August 10, 2021
Assignee:
PRELLIS BIOLOGICS, INC.
Inventors:
Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
Abstract: The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors.
Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
Type:
Grant
Filed:
July 24, 2018
Date of Patent:
December 24, 2019
Assignee:
PRELLIS BIOLOGICS, INC.
Inventors:
Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton