Patents Assigned to Procrea BioSciences Inc.
  • Patent number: 6376201
    Abstract: It is an object of the present invention to provide the clinicians with a new application for ligands specific to MHC-class I antigens, especially HLA-ABC antigens, this new application residing in the detection and diagnosis of endometriosis. It is also an object of the present invention to provide a method and a test kit for diagnosing endometriosis, preferably by immunohistochemistry, using a monoclonal anti- HLA-ABC antibody as a preferred ligand or diagnostic reagent. This new method is non-invasive and is more reliable as a screening test than the conventionally used laparoscopy. When the endometrium of a woman tests negatively with the claimed method, it prevents the use of laparoscopy which is an invasive method for detecting endometriosis. This method can be practised on a specimen obtained from the endometrium of a patient and does not require a specimen sampled directly from the endometriotic foci.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: April 23, 2002
    Assignee: Procrea Biosciences Inc.
    Inventors: Pierre Miron, Marie-Hélène Lachapelle, Denis-Claude Roy
  • Publication number: 20010006782
    Abstract: It is an object of the present invention to provide the clinicians with a new application for ligands specific to MHC-class I antigens, especially HLA-ABC antigens, this new application residing in the detection and diagnosis of endometriosis. It is also an object of the present invention to provide a method and a test kit for diagnosing endometriosis, preferably by immunohistochemistry, using a monoclonal anti-HLA-ABC antibody as a preferred ligand or diagnostic reagent. This new method is non-invasive and is more reliable as a screening test than the conventionally used laparoscopy. When the endometrium of a woman tests negatively with the claimed method, it prevents the use of laparoscopy which is an invasive method for detecting endometriosis. This method can be practised on a specimen obtained from the endometrium of a patient and does not require a specimen sampled directly from the endometriotic foci.
    Type: Application
    Filed: March 2, 1999
    Publication date: July 5, 2001
    Applicant: PROCREA BIOSCIENCES INC.
    Inventors: Pierre Miron, MARIE-HELENE LACHAPELLE, DENIS-CLAUDE ROY
  • Patent number: 6251592
    Abstract: The present invention relates to novel STR markers for DNA fingerprinting. More specifically, the invention relates to seven different STR markers for DNA fingerprinting of a DNA sample, whereby each marker comprises a sequence selected from the group consisting of SEQ ID NOS:1 to 7 as set forth in FIGS. 1A-1B.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: June 26, 2001
    Assignee: Procrea BioSciences Inc.
    Inventors: JianQing Tang, Serge B. Melançon
  • Patent number: 6060243
    Abstract: Disclosed is a DNA amplification primer pair for the amplification of Sextolet 900 marker, which comprises R14B/264 primer having the sequence of SEQ ID NO:1 and a primer designed from the nucleic acid sequence of Sextolet 900 marker (SEQ ID NO:2). A method for the DNA fingerprinting identification of genetically related or unrelated individuals, which comprises the steps of performing DNA amplification of genomic DNA samples collected from individuals, using the primer pair R14B/264 and Sext.900E (SEQ ID NO:1 and SEQ ID NO:3, respectively) and separating the amplified DNA segments obtained whereby Sextolet 900 marker, having a heterozigosity of at least 0.97 and comprising more than 64 alleles, is amplified and serves as DNA fingerprinting of the individuals.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: May 9, 2000
    Assignee: Procrea BioSciences Inc.
    Inventors: Jian Qing Tang, Serge B. Melancon