Abstract: Devices and methods are disclosed for managing and/or treating body tissues obstructing a hollow body lumen, including the prostatic lobe tissues obstructing the urethra, for example conditions including benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), benign prostatic obstruction (BPO) and associated lower urinary tract symptoms (LUTS). A retrieval sheath having an elongated shaft member with at least one region of modified flexibility that is configured compress the implant to a reduced profile for removal from the patient's body.

Abstract: A locking irrigation valve with is disclosed that features a valve body having a lumen, an irrigation port in fluid communication with the lumen, a connector configured couple to a cystoscope so that the lumen is aligned with a working channel of the cystoscope, a collet having a compressible inner bore and a lock configured to engage the collet and compress the inner bore.

Abstract: Devices and methods are disclosed for managing and/or treating body tissues obstructing a hollow body lumen, such as the prostatic lobe tissues obstructing the urethra. A scaffolding may be provided with opposing tissue-engaging portions and at least one expansion member configured to transition between a compressed configuration having a reduced distance between the tissue-engaging portions and a deployed configuration having an increased distance between the tissue-engaging portions.

Abstract: Devices and methods are disclosed for determining prostatic urethral length. A measuring device having an elongated shaft member with associated markings may be advanced through a working channel of the cystoscope so that a positioning aid disposed on the elongated shaft member is located at a bladder neck of the patient. A first position of the elongated shaft member is determined using the markings. The elongated shaft member is then withdrawn to a second position at which the positioning aid is located at the patient's verumontanum. The prostatic urethral length is determined based at least in part on relative translational movement of the elongated shaft member between the first position and the second position using the markings.

Abstract: Devices and methods are disclosed for determining prostatic urethral length. A measuring device having an elongated shaft member with associated markings may be advanced through a working channel of the cystoscope so that a positioning aid disposed on the elongated shaft member is located at a bladder neck of the patient. A first position of the elongated shaft member is determined using the markings. The elongated shaft member is then withdrawn to a second position at which the positioning aid is located at the patient's verumontanum. The prostatic urethral length is determined based at least in part on relative translational movement of the elongated shaft member between the first position and the second position using the markings.

Abstract: Devices and methods are disclosed for determining prostatic urethral length. A measuring device having an elongated shaft member with associated markings may be advanced through a working channel of the cystoscope so that a positioning aid disposed on the elongated shaft member is located at a bladder neck of the patient. A first position of the elongated shaft member is determined using the markings. The elongated shaft member is then withdrawn to a second position at which the positioning aid is located at the patient's verumontanum. The prostatic urethral length is determined based at least in part on relative translational movement of the elongated shaft member between the first position and the second position using the markings.

Abstract: The invention is devices and methods to treat benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms infections (LUTS). The devices are intra-urethral implants placed in a patient in need thereof by minimally invasive procedures, preferably under local anesthesia in an office environment. The devices are sized and designed for atraumatic insertion and expansion within the urethra to engage and retract enlarged prostatic tissue proximate to the urethra that is leading to adverse symptoms associated with BPH. The methods include steps to deploy the implant devices of the invention using a delivery system of the invention and at target prostatic tissue that is visualized during the procedure and yields a reduction in the symptoms of BPH.

Abstract: An self-actuating grasping device and corresponding method of using the grasping device for retrieving a foreign object from a location in a patient's body. The grasping device has a handle with a self-actuating mechanism, an actuator on the handle coupled to an actuator wire, an elongated shaft member extending distally from the handle with the actuation wire coaxially disposed therein and opposing jaws at a distal end of the elongated shaft member that are coupled to the actuation wire and pivot between open and closed configurations. The self-actuating mechanism has a bias that imparts a closing force to the opposing jaws through the actuation wire. Actuation of the actuator is configured to impart an opening force to the opposing jaws through the actuation wire.