Abstract: Provided herein are soluble engineered polypeptides for oxidizing hydrocarbons, and methods of use, manufacture, and design thereof. In particular, soluble, polypeptides capable of oxidizing methane to methanol (e.g., hydroxylation) are provided.
Type:
Grant
Filed:
March 9, 2016
Date of Patent:
February 20, 2018
Assignees:
NORTHWESTERN UNIVERSITY, PROTABIT, LLC, CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Amy C Rosenzweig, Thomas J. Lawton, Alex Nisthal, Jan S. Kostecki, Heidi K. Privett, Frederick Lee, Barry Olafson, Athanasios D. Dousis