Patents Assigned to Provid Pharmaceuticals, Inc.
  • 7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(1H)-ONE, ANALOGS THEREOF, AND SALTS THEREOF AND METHODS FOR THEIR USE IN THERAPY
    Publication number: 20170096431
    Abstract: This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10): as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.
    Type: Application
    Filed: February 22, 2016
    Publication date: April 6, 2017
    Applicants: ONCOCEUTICS INC., PROVID PHARMACEUTICALS INC.
    Inventors: Joshua E. Allen, Martin Stogniew, Richard S. Pottorf, Bhaskara Rao Nallaganchu, Gary Olson, Yanjun Sun
  • Antibacterial agents: aryl myxopyronin derivatives
    Patent number: 9592221
    Abstract: The invention provides compounds of formula Ia, Ib and Ic: and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: March 14, 2017
    Assignees: Rutgers, The State University of New Jersey, Provid Pharmaceuticals Inc.
    Inventors: Richard H. Ebright, Yon W. Ebright, Juan Shen, James Bacci, Anne-Cecile Hiebel, William Solvibile, Christopher Self, Gary Olson
  • ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES
    Publication number: 20160263083
    Abstract: The invention provides compounds of formula Ia, Ib and Ic: and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
    Type: Application
    Filed: March 8, 2016
    Publication date: September 15, 2016
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, PROVID PHARMACEUTICALS INC.
    Inventors: Richard H. EBRIGHT, Yon W. EBRIGHT, Juan SHEN, James BACCI, Anne-Cecile HIEBEL, William SOLVIBILE, Christopher SELF, Gary OLSON
  • Antibacterial agents: aryl myxopyronin derivatives
    Patent number: 9315495
    Abstract: The invention provides compounds of formula la, lb and Ic: [Formula Ia, Ib, and Ic] and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: April 19, 2016
    Assignees: Rutgers, The State University of New Jersey, Provid Pharmaceuticals Inc.
    Inventors: Richard H. Ebright, Yon W. Ebright, Juan Shen, James Bacci, Anne-Cecile Hiebel, William Solvibile, Christopher Self, Gary Olson
  • Kinase inhibitors, compositions thereof, and methods of use therewith
    Patent number: 8765802
    Abstract: Provided herein are Compounds having the following structure: wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: July 1, 2014
    Assignees: Provid Pharmaceuticals, Inc., United States of America as represented by the Department of Health and Human Resources NIH
    Inventors: Robert Shoemaker, John Cardellina, Michael Currens, Sudhir Kondapaka, Yves Pommier, Andy Jobson, Dominic Scudiero, David Waugh, George Lountos, Guangtao Zhang, Andrew Colasanti, Christopher R. Self, Janet Cicariello Cook
  • Inhibitors of antigen presentation by MHC class II molecules
    Patent number: 8598312
    Abstract: The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: December 3, 2013
    Assignee: Provid Pharmaceuticals, Inc.
    Inventors: Gary Lee Olson, Charles Michael Cook, Christopher Raymond Self
  • Methods for the use of inhibitors of antigen presentation by MHC class II molecules
    Patent number: 8222215
    Abstract: The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: July 17, 2012
    Assignee: Provid Pharmaceuticals, Inc.
    Inventors: Gary Lee Olson, Charles Michael Cook, Christopher Raymond Self
  • Inhibitors of antigen presentation by MHC class II molecules and methods of use thereof
    Patent number: 7439231
    Abstract: The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: October 21, 2008
    Assignee: Provid Pharmaceuticals, Inc.
    Inventors: Gary Olson, Charles Cook, Christopher Self