Abstract: The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.
Type:
Application
Filed:
November 17, 2011
Publication date:
February 6, 2014
Applicants:
PROVIDENCE HEALTH & SERVICES-OREGON D/B/A PROVIDEN CE PORTLAND MEDICAL CENTER, ADURO BIOTECH