Abstract: Disclosed is a composition for preventing and treating acetaminophen induced liver injury including the protein extracted from Porphyra yezoensis. The protein(s), separated and purified from hot water extracts of Porphyra yezoensis, having the molecular weight of 14 kDa measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis, has an excellent effect for inhibiting the oxidative injury of liver tissue and cell apoptosis of liver cells induced by acetaminophen.
Type:
Grant
Filed:
August 28, 2007
Date of Patent:
June 24, 2014
Assignee:
Pukyong National University Industry Academic Cooperation Foundation
Abstract: The present invention relates to a HIV-1 inhibiting pharmaceutical composition containing, as an active ingredient, 6,6?-bieckol which is a phloroglucinol polymer compound separated from Ecklonia cava. The Ecklonia cava-derived 6,6?-bieckol according to the present invention inhibits HIV-1 induced cell fusion, the cell lysis effect, and the cytopathogenic effect including virus p24 antibody production, exhibits RT enzyme inhibition activity and HIV-1 infection inhibition activity, and shows no cytotoxicity at the concentration that almost perfectly inhibits HIC-1 replication.
Type:
Application
Filed:
August 12, 2013
Publication date:
December 19, 2013
Applicant:
Pukyong National University Industry - Academic Cooperation Foundation
Inventors:
Moon-Moo KIM, Se-Kwon KIM, Sang-Hoon LEE
Abstract: The present invention relates to pharmaceutical compositions containing fucoidan for stimulating and activating osteogenesis. The compositions according to the present invention contain fucoidan as an active ingredient to increase the activities of alkaline phosphatase and the production of osteocalcin, and to increase the production of bone morphogenetic protein (BMP-2).
Type:
Application
Filed:
November 5, 2009
Publication date:
December 8, 2011
Applicant:
PUKYONG NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Abstract: The present invention relates to a HIV-1 inhibiting pharmaceutical composition containing, as an active ingredient, 6,6?-bieckol which is a phloroglucinol polymer compound separated from Ecklonia cava. The Ecklonia cava-derived 6,6?-bieckol according to the present invention inhibits HIV-1 induced cell fusion, the cell lysis effect, and the cytopathogenic effect including virus p24 antibody production, exhibits RT enzyme inhibition activity and HIV-1 infection inhibition activity, and shows no cytotoxicity at the concentration that almost perfectly inhibits HIC-1 replication.
Type:
Application
Filed:
September 21, 2009
Publication date:
October 20, 2011
Applicant:
Pukyong National University Industry-Academic Cooperation Foundation
Inventors:
Moon-Moo Kim, Se-Kwon Kim, Sang-Hoon Lee
Abstract: The present invention relates to the quaternized amino glucosamine, it can exert an anticancer effect via induction of apoptosis in a dose and time dependant manner through which an anticancer treatment effect can be increased.
Type:
Grant
Filed:
September 14, 2006
Date of Patent:
December 21, 2010
Assignee:
Pukyong National University Industry-Academic Cooperation Foundation
Inventors:
Moon-Moo Kim, Se-Kwon Kim, Eresha Mendis
Abstract: The present invention relates to the quarternized amino glucosamine, it can exert an anticancer effect via induction of apoptosis in a dose and time dependant manner through which an anticancer treatment effect can be increased.
Type:
Application
Filed:
September 14, 2006
Publication date:
July 9, 2009
Applicant:
Pukyong National University Industry-Academic Cooperation Foundation
Inventors:
Moon-Moo Kim, Se-Kwon Kim, Eresha Mendis