Abstract: A hemodialysis machine comprising a fluid pathway for delivering a dialysate solution, wherein the fluid pathway comprises a pre-dialysis pathway and a post-dialysis pathway, a dialyser for dialysing patient's blood using the dialysate solution, the dialyser connected between the pre-dialysis pathway and the post-dialysis pathway, a first sensor system configured to sense a characteristic of the dialysate solution at a first location on the pre-dialysis pathway, a second sensor system configured to sense a characteristic of the dialysate solution at a second location on the post-dialysis pathway, and a control system configured to make a comparative analysis of the measurements taken by the first sensor and the second sensor for monitoring the composition of the dialysate solution.

Abstract: A method of testing the rotor engagement of a peristaltic pump rotor. The method comprising steps of providing a pump system comprising a peristaltic pump rotor; a tube; a valve; a pressure sensor; a comparator; and a processor. The pressure sensor is configured to monitor the pressure in a fluid in the tube downstream of the peristaltic pump rotor and upstream of the valve. The comparator is configured to continuously monitor the pressure sensor and compare the measured fluid pressure data with a predetermined parameter. The processor is configured to receive a signal from the comparator and generate an alert signal when the measured pressure data falls outside the predetermined parameters.

Abstract: Embodiments of the present disclosure include a dialysis system having a disposable cartridge which includes one or more flowpaths arranged on or within the cartridge.

Abstract: The invention relates to a dialysis machine capable of performing ultrafiltration without the need for a dedicated ultrafiltration pump. The system uses a pair of membrane flow balance pumps wherein the operation and/or the volume flow rate of the pumps can be modified during operation to bring about a net movement of dialysate either into or from the dialyser. The direction of flow of the dialysate in the dialyzer is reversible and the dialyzer can comprise two dialysate inlets, one at each end, and two dialysate outlets, one at each end.

Abstract: Embodiments of the present disclosure include a dialysis system having a disposable cartridge which includes one or more flowpaths arranged on or within the cartridge, where the one or more flowpaths including at least one of a blood flowpath for carrying a volume of blood to be treated in a dialyser and a dialysate flowpath, isolated from the blood flowpath, for delivering a flow of dialysate solution through the dialyser.