Patents Assigned to Queen Mary and Westfield College, University of London
  • Publication number: 20130202604
    Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence (SEQ?ID?NO:?1) MILNSSTEDG?IKRIQDDCPK?AGRHNYIFVM?IPTLYSIIFV?VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.
    Type: Application
    Filed: January 24, 2013
    Publication date: August 8, 2013
    Applicants: Queen Mary & Westfield College, University of London
    Inventors: Queen Mary & Westfield College, University of London, Gavin Paul Vinson, John Richard Puddefoot
  • Patent number: 8383108
    Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence MILNSSTEDG IKRIQDDCPK AGHRHNYIFVM IPTLYSIIFV VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: February 26, 2013
    Assignee: Queen Mary & Westfield College, University of London
    Inventors: Gavin Paul Vinson, John Richard Puddefoot, Stewart Barker
  • Publication number: 20130041446
    Abstract: The present invention provides a method of abdominal pain relief in a subject comprising the steps of: identifying sub-diaphragmatic vagus nerve branches; applying an electrode to said nerve branch; stimulating the subject's vagus nerve branch by the application of electrical pulses through said electrode to said nerve in a given pattern and at a rate controlled by a controller such as to relieve pain. The electrical pulse may be applied at a number of frequencies, for a given duration with a given rest period and may be of a given magnitude, to control the pain experienced by the patient. In an example arrangement the stimulation is applied to the vagus branch of the celiac branch or posterior vagal trunk of the sub-diaphragmatic vagus nerve.
    Type: Application
    Filed: August 8, 2012
    Publication date: February 14, 2013
    Applicant: Queen Mary & Westfield College, University of London
    Inventor: Charles Henry Knowles
  • Publication number: 20120225793
    Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
    Type: Application
    Filed: March 1, 2012
    Publication date: September 6, 2012
    Applicants: The United States of America, as Represented by the Secretary, Dept. of Health and Human Services, Board of Regents of the University of Nebraska, University of Rochester, Arizona Board of Regents on Behalf of the University of Arizona, Universitat De Barcelona, Queen Mary and Westfield College, University of London, Hospital Clinic, Julius-Maximilians-University of Wuerzburg, British Columbia Cancer Agency Branch, Oslo University Hospital HE, Fundacio Clinic
    Inventors: Louis M. Staudt, George Wright, Sandeep Dave, Bruce Tan, John I. Powell, Wyndham Wilson, Elaine Jaffe, Wing C. Chan, Timothy C. Greiner, Dennis Weisenburger, James Armitage, Kai Fu, Richard I. Fisher, Lisa Rimsza, Thomas Miller, Thomas Grogan, Elias Campo, Silvia M. Bea, Itziar Salaverria, Armando Lopez-Guillermo, Emili Montserrat, Victor Moreno, Andreas Zetti, German Ott, Hans-Konrad Muller-Hermelink, Andreas Rosenwald, Julie Vose, Randy Gascoyne, Joseph Connors, Erlend Smeland, Stein Kvaloy, Harald Holte, Jan Delabie, T. Andrew Lister
  • Publication number: 20120177575
    Abstract: A delivery vehicle, for delivering a pharmaceutically active agent or a marker to a cell, comprising a ligand binding portion specific for a Fas Ligand, and a carrier for the pharmaceutically active agent or marker.
    Type: Application
    Filed: July 21, 2010
    Publication date: July 12, 2012
    Applicant: Queen Mary & Westfield College University of London
    Inventors: Davidson Day Ateh, Joanne Elizabeth Martin
  • Publication number: 20120145806
    Abstract: Apparatus for dispensing a powder, comprises a dispensing nozzle having an upper portion for containing a quantity of the powder, having a minimum internal horizontal dimension of 5 mm, and a dispensing orifice below the upper portion, with a maximum internal horizontal dimension of from 200 ?m to 3 mm. An internal passage leading from the said upper portion to the dispensing orifice tapers in a linear manner from its upper end to its lower end. The apparatus includes a transducer for applying vibrational pulses to the dispensing nozzle, to dispense doses of powder from the orifice. Vibrational pulses are controlled to control flow of powder through the nozzle.
    Type: Application
    Filed: August 18, 2010
    Publication date: June 14, 2012
    Applicant: Queen Mary & Westfield College, University of London
    Inventor: Shoufeng Yang
  • Patent number: 8131475
    Abstract: Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: March 6, 2012
    Assignees: The United States of America as represented by the Secretary, Department of Health and Human Services, Board of Regents of the University of Nebraska, University of Rochester, Arizona Board of Regents of Behalf of the University of Arizona, Universitat de Barcelona, Fundacio Clinic, Hospital Clinic, Julius-Maximilians-University of Wuerzburg, British Columbia Cancer Agency Branch, Oslo University Hospital HF, Queen Mary and Westfield College, University of London
    Inventors: Louis M. Staudt, George Wright, Sandeep Dave, Bruce Tan, John I. Powell, Wyndham Wilson, Elaine Jaffe, Wing C. Chan, Timothy C. Greiner, Dennis Weisenburger, James Armitage, Kai Fu, Richard I. Fisher, Lisa Rimsza, Thomas Miller, Thomas Grogan, Elias Campo, Silvia M Bea, Itziar Salaverria, Armando Lopez-Guillermo, Emili Montserrat, Victor Moreno, Andreas Zettl, German Ott, Hans-Konrad Muller-Hermelink, Andreas Rosenwald, Julie Vose, Randy Gascoyne, Joseph Connors, Erlend Smeland, Stein Kvaløy, Harald Holte, Jan Delabie, T. Andrew Lister
  • Patent number: 7822231
    Abstract: The optical flow in an image is estimated using only parameters extracted directly from a compressed video data stream, substantially eliminating the need to decode the video data stream for this purpose. Coefficients extracted from the compressed video data stream are used to establish a confidence map indicative of the edge strength within the image data and hence the accuracy of the associated motion field. A smooth motion field is generated from the motion vectors inherent in the compressed video data stream. The motion field is then used to update the confidence map between frames, providing an estimate of the optical flow.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: October 26, 2010
    Assignee: Queen Mary and Westfield College, University of London
    Inventors: Miguel Coimbra, Michael Evan Davies
  • Patent number: 6514616
    Abstract: A thermal management device includes an isotropic carbon encapsulated in an encapsulating material that improves the strength of the carbon. The encapsulating material may be e.g. polyimide, epoxy resin, acrylic, polyurethane, polyester, or any other suitable polymer.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: February 4, 2003
    Assignee: Queen Mary and Westfield College, University of London
    Inventors: Angelo Gandi, Rui De Oliveira, Anthony Arthur Carter