Patents Assigned to RAFAEL PHARMACEUTICALS, INC.
  • DEUTERATED DERIVATIVES OF 6,8-BIS(BENZYLSULFANYL)OCTANOIC ACID
    Publication number: 20230348373
    Abstract: The invention provides new deuterated derivatives of 6,8-bis(benzylsulfanyl)octanoic acid, pharmaceutical compositions thereof, and methods for treating cancer with the new compositions.
    Type: Application
    Filed: July 10, 2020
    Publication date: November 2, 2023
    Applicant: Rafael Pharmaceuticals, Inc.
    Inventors: Sol J. Barer, Yanchao Xin, Yaping Hong, Gang Zhou
  • Methods of treating leukemia using compositions containing bis(benzylthio)octanoic acid and ion pairs thereof
    Patent number: 11065335
    Abstract: Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment of medical disorders, such as cancer.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: July 20, 2021
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Pharmaceutical compounds
    Patent number: 10526357
    Abstract: Therapeutically-effective amounts of novel analogs or derivatives of alkyl fatty acids, such as but not limited to lipoic acid, and pharmaceutical formulations comprising such analogs or derivatives and pharmaceutically-acceptable carriers therefor, are useful for the treatment, prevention, imaging, and/or diagnosis of medical disorders.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: January 7, 2020
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert Shorr, Robert Rodriguez, Paul Bingham, Lakmal Boteju, Thomas Kwok, James Marecek
  • Pharmaceutical compounds
    Patent number: 10450337
    Abstract: Therapeutically-effective amounts of novel analogs or derivatives of alkyl fatty acids, such as but not limited to lipoic acid, and pharmaceutical formulations comprising such analogs or derivatives and pharmaceutically-acceptable carriers therefor, are useful for the treatment, prevention, imaging, and/or diagnosis of medical disorders.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: October 22, 2019
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert Shorr, Robert Rodriguez, Paul Bingham, Lakmal Boteju, Thomas Kwok, James Marecek
  • Methods for treating cancer using 6,8-bis (benzylthio) octanonic acid
    Patent number: 10391177
    Abstract: Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment of medical disorders, such as cancer.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: August 27, 2019
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Pharmaceutical compounds
    Patent number: 10179796
    Abstract: Therapeutically-effective amounts of novel analogs or derivatives of alkyl fatty acids, such as but not limited to lipoic acid, and pharmaceutical formulations comprising such analogs or derivatives and pharmaceutically-acceptable carriers therefor, are useful for the treatment, prevention, imaging, and/or diagnosis of medical disorders.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: January 15, 2019
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert Shorr, Robert Rodriguez, Paul Bingham, Lakmal Boteju, Thomas Kwok, James Marecek
  • Pharmaceutical formulations containing lipoic acid derivatives
    Patent number: 10098955
    Abstract: Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment of medical disorders, such as cancer.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: October 16, 2018
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Methods of treating myeloma and lymphoma using compositions containing an ion pair of a lipoic acid derivative
    Patent number: 9872845
    Abstract: The invention provides a method of treating myeloma and lymphoma using a pharmaceutical composition containing a pharmaceutically acceptable diluent along with an ion pair formed by triethanolamine and a compound of Formula I:
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: January 23, 2018
    Assignee: Rafael Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Methods of treating pancreatic and ovarian cancers using compositions containing an ion pair of a lipoic acid derivative
    Patent number: 9839691
    Abstract: Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment of medical disorders, such as cancer.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: December 12, 2017
    Assignee: RAFAEL PHARMACEUTICALS, INC.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin