Abstract: A plurality of large maximized internal volume freely nestable pipette tips for mounting in a standard pipette tip rack or refill pack including a horizontally extending pipette tip support having a plurality of through holes arranged in an array, each hole having a center which is spaced a distance "s" from centers of immediately adjacent through holes, each pipette tip having a substantially cylindrical proximal portion and an elongated generally conical distal portion coaxial with and joined to its proximal portion adjacent a downward facing outwardly extending shoulder and including at a distal end of the tip a relatively small orifice for receiving and dispensing fluid into and from the pipette tip upon operation of a pipette to which the pipette tip is mounted, the proximal portion of each pipette tip having an outer diameter equal to or slightly less than "s" and a slightly conical inner surface for tightly receiving and releasably attaching to a pipette tip mounting shaft of a large volume pipette and