Patent number: 12065464
Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
Type:
Grant
Filed:
June 25, 2021
Date of Patent:
August 20, 2024
Assignee:
REATA PHARMACEUTICALS HOLDINGS, LLC
Inventors:
Eric Anderson, Xiaofeng Liu, Andrea Decker
Publication number: 20240228528
Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
Type:
Application
Filed:
January 12, 2024
Publication date:
July 11, 2024
Applicant:
REATA PHARMACEUTICALS HOLDINGS, LLC
Inventors:
Ahmad Y. SHEIKH, Alessandra MATTEI, Xiu C. WANG
Patent number: 11873320
Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.
Type:
Grant
Filed:
August 6, 2021
Date of Patent:
January 16, 2024
Assignee:
REATA PHARMACEUTICALS HOLDINGS, LLC
Inventors:
Ahmad Y. Sheikh, Alessandra Mattei, Xiu C. Wang