Abstract: The present invention provides antibodies that bind to angiopoietin-2 (Ang-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human Ang-2. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more Ang-2 biological activities including angiogenesis.
Type:
Grant
Filed:
January 23, 2013
Date of Patent:
March 17, 2015
Assignee:
Regeneron Pharamceuticals, Inc.
Inventors:
Israel Lowy, Gavin Thurston, Christopher Daly