Patents Assigned to Regent Court Technologies
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Patent number: 6929811Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: GrantFiled: March 26, 2003Date of Patent: August 16, 2005Assignee: Regent Court Technologies, LLCInventors: Jonnie R. Williams, Robert J. DeLorenzo, Harold R. Burton
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Publication number: 20050176777Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: ApplicationFiled: April 11, 2005Publication date: August 11, 2005Applicant: Regent Court TechnologiesInventors: Jonnie Williams, Robert DeLorenzo, Harold Burton
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Publication number: 20050109357Abstract: A method of treating tobacco to reduce the content of, or prevent formation of, harmful nitrosamines which are normally found in tobacco is disclosed. The method includes the step of subjecting at least a portion of the plant, while the portion is uncured and in a state susceptible to having the amount of nitrosamines reduced or formation of nitrosamines arrested, to a controlled environment capable of providing a reduction in the amount of nitrosamines or prevention of the formation of nitrosamines, for a time sufficient to reduce the amount of or substantially prevent the formation of at least one nitrosamine, wherein the controlled environment is provided by controlling at least one of humidity, rate of temperature change, temperature, airflow, CO level, CO2 level, O2 level, and arrangement of the tobacco plant. Tobacco products and an apparatus for producing such tobacco products are also disclosed.Type: ApplicationFiled: December 29, 2004Publication date: May 26, 2005Applicant: Regent Court Technologies LLCInventor: Jonnie Williams
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Patent number: 6834654Abstract: A smokeless tobacco product suitable for human consumption is prepared from powdered tobacco. In one aspect, the powdered tobacco has a collective content of N′-nitrosonornicotine (NNN), 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK), N′-nitrosoanatabine (NAT) and N′-nitrosoanabasine (NAB) which is 0.3 &mgr;g/g or less. In another aspect, a smokeless tobacco product comprises powdered tobacco and from about 0.5 to about 15 wt % peppermint, from about 0.5 to about 15 wt % spearmint, from about 0.5 to about 15 wt % menthol, and from about 0.5 to about 15 wt % eucalyptus. The powdered tobacco can be prepared by pulverizing cured tobacco or, alternatively, from an aqueous extract of tobacco.Type: GrantFiled: April 30, 2002Date of Patent: December 28, 2004Assignee: Regent Court Technologies, LLCInventor: Jonnie R. Williams
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Publication number: 20030185908Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: ApplicationFiled: March 26, 2003Publication date: October 2, 2003Applicant: Regent Court TechnologiesInventors: Jonnie R. Williams, Robert J. DeLorenzo, Harold R. Burton
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Patent number: 6569470Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: GrantFiled: January 11, 2002Date of Patent: May 27, 2003Assignee: Regent Court Technologies, LLCInventors: Jonnie R. Williams, Robert J. DeLorenzo, Harold R. Burton
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Publication number: 20020174874Abstract: A method of treating tobacco to reduce the content of, or prevent formation of, harmful nitrosamines which are normally found in tobacco is disclosed. The method includes the step of subjecting at least a portion of the plant, while the portion is uncured and in a state susceptible to having the amount of nitrosamines reduced or formation of nitrosamines arrested, to a controlled environment capable of providing a reduction in the amount of nitrosamines or prevention of the formation of nitrosamines, for a time sufficient to reduce the amount of or substantially prevent the formation of at least one nitrosamine, wherein the controlled environment is provided by controlling at least one of humidity, rate of temperature change, temperature, airflow, CO level, CO2 level, O2 level, and arrangement of the tobacco plant. Tobacco products and an apparatus for producing such tobacco products are also disclosed.Type: ApplicationFiled: May 9, 2002Publication date: November 28, 2002Applicant: Regent Court Technologies LLCInventor: Jonnie R. Williams
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Patent number: 6425401Abstract: A method of treating tobacco to reduce the content of, or prevent formation of, harmful nitrosamines which are normally found in tobacco is disclosed. The method includes the step of subjecting at least a portion of the plant, while the portion is uncured and in a state susceptible to having the amount of nitrosamines reduced or formation of nitrosamines arrested, to a controlled environment capable of providing a reduction in the amount of nitrosamines or prevention of the formation of nitrosamines, for a time sufficient to reduce the amount of or substantially prevent the formation of at least one nitrosamine, wherein the controlled environment is provided by controlling at least one of humidity, rate of temperature change, temperature, airflow, CO level, CO2 level, O2 level, and arrangement of the tobacco plant. Tobacco products and an apparatus for producing such tobacco products are also disclosed.Type: GrantFiled: September 25, 2000Date of Patent: July 30, 2002Assignee: Regent Court Technologies LLCInventor: Jonnie R. Williams
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Publication number: 20020054926Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, anti-depression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: ApplicationFiled: January 11, 2002Publication date: May 9, 2002Applicant: Regent Court TechnologiesInventors: Jonnie R. Williams, Robert J. DeLorenzo, Harold R. Burton
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Patent number: 6350479Abstract: The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamaté extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The MAO inhibitors of the present invention can cause an increase in the level of norepinephrine, dopamine, and serotonin in the brain and other tissues, and thus can cause a wide variety of pharmacological effects mediated by their effects on these compounds. The MAO inhibitors of the present invention are useful for a variety of therapeutic applications, such as the treatment of depression, disorders of attention and focus, mood and emotional disorders, Parkinson's disease, extrapyramidal disorders, hypertension, substance abuse, smoking substitution, antidepression therapy, eating disorders, withdrawal syndromes, and the cessation of smoking.Type: GrantFiled: June 4, 1999Date of Patent: February 26, 2002Assignee: Regent Court TechnologiesInventors: Jonnie R. Williams, Robert J. Delorenzo, Harold R. Burton
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Patent number: 6338348Abstract: Methods of reducing the content of and preventing formation of carcinogenic nitrosamines in harvested leafy plants such as tobacco and marijuana, are disclosed. The methods are directed to subjecting the plant to microwave radiation, at appropriate times in the cure cycle. With tobacco, products suitable for human consumption, such as cigarettes, cigars, etc., can be made in accordance with the present invention, having contents of tobacco-specific nitrosamines on a par with fresh-cut, green tobacco. In preferred embodiments, the resultant tobacco products are dried, golden-yellow leaves having almost negligible amounts of the known carcinogens NNN and NNK, in comparison to conventionally cured tobacco.Type: GrantFiled: February 12, 1999Date of Patent: January 15, 2002Assignee: Regent Court TechnologiesInventor: Jonnie R. Williams
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Patent number: 6311695Abstract: Methods of reducing the content of and preventing formation of carcinogenic nitrosamines in harvested leafy plants such as tobacco and marijuana, are disclosed. The methods are directed to subjecting the plant to microwave and/or higher frequency radiation, at appropriate times in the cure cycle. With tobacco, products suitable for human consumption, such as cigarettes, cigars, etc., can be made in accordance with the present invention, having contents of tobacco-specific nitrosamines on a par with fresh-cut, green tobacco. In preferred embodiments, the resultant tobacco products are dried, golden-yellow leaves having almost negligible amounts of the known carcinogens NNN and NNK, in comparison to conventionally cured tobacco.Type: GrantFiled: March 18, 1999Date of Patent: November 6, 2001Assignee: Regent Court TechnologiesInventor: Jonnie R. Williams
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Patent number: 6202649Abstract: A method of treating tobacco to reduce the content of, or prevent formation of, harmful nitrosamines which are normally found in tobacco is disclosed. The method includes the step of subjecting at least a portion of the plant, while the portion is uncured and in a state susceptible to having the amount of nitrosamines reduced or formation of nitrosamines arrested, to a controlled environment capable of providing a reduction in the amount of nitrosamines or prevention of the formation of nitrosamines, for a time sufficient to reduce the amount of or substantially prevent the formation of at least one nitrosamine, wherein the controlled environment is provided by controlling at least one of humidity, rate of temperature change, temperature, airflow, CO level, CO2 level, O2 level, and arrangement of the tobacco plant. Tobacco products and an apparatus for producing such tobacco products are also disclosed.Type: GrantFiled: September 15, 1999Date of Patent: March 20, 2001Assignee: Regent Court TechnologiesInventor: Jonnie R. Williams
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Patent number: 6135121Abstract: Methods of reducing the content of and preventing formation of carcinogenic nitrosamines in harvested leafy plants such as tobacco and marijuana, are disclosed. The methods are directed to subjecting the plant to microwave radiation, at appropriate times in the cure cycle. With tobacco, products suitable for human consumption, such as cigarettes, cigars, etc., can be made in accordance with the present invention, having contents of tobacco-specific nitrosamines on a par with fresh-cut, green tobacco. In preferred embodiments, the resultant tobacco products are dried, golden-yellow leaves having almost negligible amounts of the known carcinogens NNN and NNK, in comparison to conventionally cured tobacco.Type: GrantFiled: June 20, 1997Date of Patent: October 24, 2000Assignee: Regent Court TechnologiesInventor: Jonnie R. Williams
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Patent number: 5845647Abstract: Tobacco products improved by the use of uncured, green tobacco and propolis for use in smoking tobacco, chewing tobacco, tobacco chewing gum, beverages and foods. In one preferred embodiment green tobacco provides reduced carcinogenic nitrosamines. In another preferred embodiment, the addition of propolis reduces bitterness, prolongs flavor and shelf life, and reduces tar and particulate content. The tobacco products can be used to reduce smoking withdrawal symptoms such as irritability and weight gain by providing nicotine and monoamine oxidase B inhibitor. Further, the invention can be used to treat Alzheimer's disease and to manage weight control in non-smokers.Type: GrantFiled: June 28, 1996Date of Patent: December 8, 1998Assignee: Regent Court TechnologiesInventors: Francis E. O'Donnell, Jr., Jonnie R. Williams
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Patent number: 5803081Abstract: Tobacco products improved by the use of uncured, yellow tobacco low in tar and carcinogenic nitrosamines, treated by microwaving, or convection heating, or freeze drying to kill microbes responsible for curing, for use in smoking tobacco, chewing tobacco, tobacco chewing gum, beverages and foods. In one preferred embodiment tobacco, uncured or cured, is microwaved to reduce further tar and carcinogenic nitrosamines.Type: GrantFiled: December 2, 1996Date of Patent: September 8, 1998Assignee: Regent Court TechnologiesInventors: Francis E. O'Donnell, Jr., Jonnie R. Williams
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Patent number: RE38123Abstract: Methods of reducing the content of and preventing formation of carcinogenic nitrosamines in harvested leafy plants such as tobacco and marijuana, are disclosed. The methods are directed to subjecting the plant to microwave radiation, at appropriate times in the cure cycle. With tobacco, products suitable for human consumption, such as cigarettes, cigars, etc., can be made in accordance with the present invention, having contents of tobacco-specific nitrosamines on a par with fresh-cut, green tobacco. In preferred embodiments, the resultant tobacco products are dried, golden-yellow leaves having almost negligible amounts of the known carcinogens NNN and NNK, in comparison to conventionally cured tobacco.Type: GrantFiled: May 22, 2001Date of Patent: May 27, 2003Assignee: Regent Court Technologies, LLC.Inventor: Jonnie R. Williams