Patents Assigned to Regents of the Univeristy of Minnesota
  • Patent number: 10760208
    Abstract: Described herein is a continuous process for modifying the properties of polyester and polyester based fibers, such as a poly(butylene terephthalate) (PBT) fiber, comprising subjecting the PBT fiber to alkaline hydrolysis, and optionally further comprising functionalizing the PBT fiber by solution grafting such as fluorination. The alkaline hydrolysis and optionally subsequent functionalization such as fluorination process can be continuous, following the melt blowing/spinning or spun-bonding process. Also described is a nonwoven PBT fiber mat obtained by the surface modification process. Further described is a filtration device comprising the nonwoven PBT fiber mat.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 1, 2020
    Assignees: CUMMINS FILTRATION IP, INC, REGENTS OF THE UNIVERISTY OF MINNESOTA
    Inventors: Zaifei Wang, Frank S. Bates, Christopher W. Macosko, Kan Wang, William C. Haberkamp, Christopher E. Holm
  • Patent number: 9549827
    Abstract: An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: January 24, 2017
    Assignees: U.S. DEPARTMENT OF VETERANS AFFAIRS, REGENTS OF THE UNIVERISTY OF MINNESOTA
    Inventors: Andrew H. Hansen, Eric A. Nickel
  • Patent number: 8585691
    Abstract: Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: November 19, 2013
    Assignee: Regents of the Univeristy of Minnesota
    Inventor: Erik N. K. Cressman
  • Publication number: 20120183944
    Abstract: The invention provides for methods and materials to decellularize an organ or portion thereof and to recellularize such a decellularized organ or portion thereof to thereby generate an organ or portion thereof.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 19, 2012
    Applicant: Regents of the Univeristy of Minnesota
    Inventors: Doris Taylor, Harald Ott
  • Publication number: 20120092010
    Abstract: Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component.
    Type: Application
    Filed: April 1, 2010
    Publication date: April 19, 2012
    Applicant: Regents of the Univeristy of Minnesota
    Inventors: Curtis A. Corum, Djaudat S. Idiyatullin, Steen Moeller, Michael G. Garwood
  • Publication number: 20100150876
    Abstract: The present invention relates to endodermal progenitor cells and methods of isolation, culture, differentiation and use thereof.
    Type: Application
    Filed: November 26, 2007
    Publication date: June 17, 2010
    Applicant: Regents of the Univeristy of Minnesota
    Inventors: Catherine Verfaillie, Lucas Chase
  • Patent number: 7255848
    Abstract: A process for producing hydrogen from ethanol or other alcohols. The alcohol, optionally in combination with water, is contacted with a catalyst comprising rhodium. The overall process is preferably carried out under autothermal conditions.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: August 14, 2007
    Assignee: Regents of the Univeristy of Minnesota
    Inventors: Gregg A. Deluga, Lanny D. Schmidt
  • Publication number: 20050282729
    Abstract: Included in the present invention are methods of inhibiting sperm capacitation, inhibiting the phosphorylation of a protein at tyrosine residues, inhibiting an acrosomal reaction, and inhibiting fertilization of an egg by sperm with the administration of a CRISP polypeptide.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 22, 2005
    Applicant: Regents of the Univeristy of Minnesota
    Inventors: David Hamilton, Kenneth Roberts, Kathy Ensrud
  • Patent number: 5849936
    Abstract: A method for the synthesis of bis-tetrahydrofranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis-tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)-hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: December 15, 1998
    Assignee: Regents of the Univeristy of Minnesota
    Inventors: Thomas R. Hoye, Lushi Tan
  • Patent number: 5285793
    Abstract: A method and apparatus for diagnosing heart rejection is disclosed. Heart rejection is diagnosed based on the pattern of interbeat intervals. The interbeat intervals of the heart are measured shortly after transplant to establish a baseline pattern. The patterns of interbeat intervals from subsequent measurements are compared to the baseline to detect changes from the baseline indicating rejection. The apparatus of the invention measures the interbeat intervals using a Schmidt trigger that detects the upstroke of the QRS and produces a corresponding pulse. The intervals between pulses are timed to produce a series of interbeat interval measurements that are stored and analyzed. Software provides for automated pattern analysis.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: February 15, 1994
    Assignee: Regents of the Univeristy of Minnesota
    Inventors: David P. Slovut, R. M. Bolman, III, Richard W. Bianco, John C. Wenstrom
  • Patent number: 4876332
    Abstract: A composition which can bind heparin and promote cellular adhesion is provided which consists essentially of a polypeptide of the formula:met-phe-lys-lys-pro-thr-pro-ser-thr-leu-lys-ala-gly-glu-leu-arg,thr-ala-gly-ser-cys-leu-arg-lys-phe-ser-thr-met,asn-pro-leu-cys-pro-pro-gly-thr-lys-ile-leu,or mixtures thereof.Medical devices such as prosthetic implants, percutaneous devices, bandages and cell culture substrates coated with the polypeptide composition are also provided.
    Type: Grant
    Filed: October 8, 1987
    Date of Patent: October 24, 1989
    Assignee: Regents of the Univeristy of Minnesota
    Inventors: Effie C. Tsilibary, Leo T. Furcht