Patents Assigned to Rehabilitation Institute of Chicago
  • Patent number: 10279157
    Abstract: Embodiments for superficial tissue compliance modulation and negative pressure wound therapy for stabilization of a chronic percutaneous implant are disclosed. An external cap is coupled to a compliance gradient of progressively decreasing stiffness. Together the external cap and compliance gradient act as a stress shield that allows forces that would otherwise act on the skin at the skin-implant interface to be dissipated over a larger area. In addition, negative pressure and fluids may be applied through negative pressure and fluid adapters, respectively, to the skin-implant interface, the status of which may be further monitored through the use of one or more sensors.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 7, 2019
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Todd A. Kuiken, Gregory A. Dumanian, Jason M. Souza
  • Publication number: 20190112580
    Abstract: This disclosure relates to the use of DNA methyltransferase inhibitors, alone or in combination with Aurora kinase inhibitors, to treat muscle cells isolated from contractured muscles or to prepare isolated and treated muscle cell compositions. The analogs or drug combinations or cell compositions can be used to treat or to prevent skeletal muscle contractures, skeletal muscle atrophy, and muscle tissue remodeling in patients such as those with cerebral palsy. A method is provided for the treatment of the conditions listed above using muscle cells treated with DNA methyltransferase inhibitors in vitro, alone or along with other active agents, cells or biocompatible materials, and transplanted into patients with cerebral palsy or other muscle conditions.
    Type: Application
    Filed: October 16, 2018
    Publication date: April 18, 2019
    Applicant: Rehabilitation Institute of Chicago d/b/a Shirley Ryan AbilityLab
    Inventors: Andrea Alberto DOMENIGHETTI, Richard L. LIEBER
  • Patent number: 10238318
    Abstract: A system and method are provided for targeted training of a person walking on a powered backward moving surface. Kinematic information of motor performance, such as ankle position and velocity, is measured throughout one or more phases of a gait cycle with a detector. The gait phase is determined, and a resistive/assistive force is applied to the leg that differs depending upon the gait phase and the measured kinematic information.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: March 26, 2019
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Ming Wu, Brian D. Schmit, T. George Hornby
  • Patent number: 10226361
    Abstract: Implementations of a quasi-passive assistive device are disclosed. Such a device may comprise a spring mechanism that increases stiffness similar to a biological ankle. In one implementation, the spring mechanism may comprise a piston, valve, springs, or other elements to match a biological stiffness profile similar to that of a biological ankle. In one implementation, an apparatus for an artificial ankle is disclosed, comprising a piston coupled to a spring and the piston connected to a valve. The spring and the piston may store energy during dorsiflexion of the ankle and the spring and the piston release energy during plantarflexion of the ankle. The piston may store and release energy through the use of the valve.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: March 12, 2019
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Luke M. Mooney, Elliott J. Rouse
  • Patent number: 10213324
    Abstract: We present a novel swing phase control module for powered transfemoral prostheses based on minimum jerk theory. The control module allows physiologically appropriate swing movement at any walking speed, regardless of the stance controller action. Preliminary validation in a transfemoral amputee subject demonstrates that the control module provides physiological swing timing, without speed or patient-specific tuning.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: February 26, 2019
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Tommaso Lenzi, Levi Hargrove, Jon Sensinger
  • Patent number: 10168262
    Abstract: A device and methods for measuring the tension applied to a suture are disclosed. In one embodiment, the device comprises a housing comprising at least one attachment point for attachment of the suture, for the device to hang from the suture when a tension is applied to the suture. The device may also comprise a force sensing unit, contained in the housing and configured to measure the amount of tension applied to the suture.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: January 1, 2019
    Assignees: Rehabilitation Institute of Chicago, Northwestern University
    Inventors: Yasin Dhaher, Matthew Patrick
  • Publication number: 20180344162
    Abstract: Systems and methods for the diagnosis of chronic pain are disclosed. An algometer comprising a pressure sensor and electrode is disclosed. The algometer may be used to measure pressure applied by a clinician at a location on a patient's body, along with EMG signals emanating from the same location of the patient. Further, a pain trigger operable by the patient may be used in coordination with the algometer. Data from the algometer and pain trigger are transmitted to a computing device and display for rendering and analysis of patient data, leading to improved diagnosis.
    Type: Application
    Filed: August 10, 2018
    Publication date: December 6, 2018
    Applicant: Rehabilitation Institute of Chicago d/b/a Shirley Ryan Ability Lab
    Inventors: Colleen M. Fitzgerald, Yasin Y. Dhaher
  • Patent number: 10070790
    Abstract: Systems and methods for the diagnosis of chronic pain are disclosed. An algometer comprising a pressure sensor and electrode is disclosed. The algometer may be used to measure pressure applied by a clinician at a location on a patient's body, along with EMG signals emanating from the same location of the patient. Further, a pain trigger operable by the patient may be used in coordination with the algometer. Data from the algometer and pain trigger are transmitted to a computing device and display for rendering and analysis of patient data, leading to improved diagnosis.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 11, 2018
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Colleen M. Fitzgerald, Yasin Y. Dhaher
  • Patent number: 10034780
    Abstract: Prosthetic devices and, more particularly, modular myoelectric prosthesis components and related methods, are described. In one embodiment, a hand for a prosthetic limb may comprise a rotor-motor; a transmission, comprising a differential roller screw; a linkage coupled to the transmission; and at least one finger coupled to the linkage. In one embodiment, a component part of a wrist of a prosthetic limb may comprise an exterior-rotor motor, a planetary gear transmission, a clutch, and a cycloid transmission. In one embodiment, an elbow for a prosthetic limb may comprise an exterior-rotor motor, and a transmission comprising a planetary gear transmission, a non-backdrivable clutch, and a screw.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: July 31, 2018
    Assignee: Rehabilitation Institute of Chicago
    Inventors: James Lipsey, Jon Sensinger
  • Patent number: 9907489
    Abstract: This disclosure relates to a hierarchy of classifiers, including linear discriminant analysis (LDA) classifiers, arranged to provide simultaneous control of multiple degrees of freedom of a prosthetic. The high accuracy of the hierarchical approach allows pattern recognition techniques to be extended to permit simultaneous control, potentially allowing amputees to produce more fluid, life-like movements, ultimately increasing their quality of life. The hierarchy may also be used to control a biological interface that allows input to computers for persons with disabilities, used as a potential video-game controller, and used as an input interface for tablets, and phones.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: March 6, 2018
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Levi Hargrove, Aaron Young
  • Patent number: 9872637
    Abstract: A medical evaluation system includes an I/O module, a processing module, and an analysis module. The I/O module receives sensory data obtained by a motion sensor disposed in a mobile device carried by a patient at least when the patient is in a non-clinical environment. The processing module extracts medically relevant data from the sensory data received from the sensor in the mobile device. The relevant data includes one or more features of interest in the sensory data. The analysis module derives one or more surrogate biomarkers from the relevant data. The surrogate biomarkers represent at least one of a state or a progression of a medical condition of the patient. The mobile device may be a mobile phone carried by the patient and the sensor may include at least one of an accelerometer or a gyroscope that generates the sensory data to represent movements of the patient.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: January 23, 2018
    Assignees: The Rehabilitation Institute of Chicago, Northwestern University
    Inventors: Konrad Kording, Mark Albert, Andrew Levien
  • Patent number: 9861499
    Abstract: A gripping device that comprises a first moveable jaw and a second fixed jaw is disclosed. The gripping device has a handle operatively engaged to the first moveable jaw and a connecting link operatively engaged to the first moveable jaw. The connecting link is positioned in at least one of a first position or a second position. The change in the position of the connecting link allows the gripping device to have either a default closed position or a default open position, which can be defined by voluntarily-open or voluntary-close modes of operation, respectively. The first moveable jaw moves in either of the modes of operation. The change in the mode of operation is accomplished through use of a connecting link that is passed through a singularity during the switching process to achieve the different output positions and directions.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: January 9, 2018
    Assignee: Rehabilitation Institute of Chicago
    Inventor: Jonathon Sensinger
  • Publication number: 20170360582
    Abstract: A magnetic and electrical interface that may be used with an assistive device. The interface comprises a proximal connector and a distal connector. The proximal connector may be attached to a liner for a residual limb and the distal connector may be attached to a hard socket or other aspect of an assistive device. Other aspects of and uses for the connector interface are also disclosed.
    Type: Application
    Filed: August 7, 2017
    Publication date: December 21, 2017
    Applicant: Rehabilitation Institute of Chicago
    Inventors: Todd Kuiken, Timothy Reissman, Elizabeth Halsne, Robert Lipschutz
  • Patent number: 9839534
    Abstract: Prosthetic devices and, more particularly, modular myoelectric prosthesis components and related methods, are described. In one embodiment, a hand for a prosthetic limb may comprise a rotor-motor; a transmission, comprising a differential roller screw; a linkage coupled to the transmission; and at least one finger coupled to the linkage. In one embodiment, a component part of a wrist of a prosthetic limb may comprise an exterior-rotor motor, a planetary gear transmission, a clutch, and a cycloid transmission. In one embodiment, an elbow for a prosthetic limb may comprise an exterior-rotor motor, and a transmission comprising a planetary gear transmission, a non-backdrivable clutch, and a screw.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: December 12, 2017
    Assignee: REHABILITATION INSTITUTE OF CHICAGO
    Inventors: James Lipsey, Jon Sensinger
  • Patent number: 9744056
    Abstract: A magnetic and electrical interface that may be used with an assistive device. The interface comprises a proximal connector and a distal connector. The proximal connector may be attached to a liner for a residual limb and the distal connector may be attached to a hard socket or other aspect of an assistive device. Other aspects of and uses for the connector interface are also disclosed.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: August 29, 2017
    Assignee: REHABILITATION INSTITUTE OF CHICAGO
    Inventors: Todd Kuiken, Timothy Reissman, Elizabeth Halsne, Robert Lipschutz
  • Patent number: 9713439
    Abstract: A system and method are provided for targeted training of a person walking on a powered backward moving surface. Kinematic information of motor performance, such as ankle position and velocity, is measured throughout one or more phases of a gait cycle with a detector. The gait phase is determined, and a resistive/assistive force is applied to the leg that differs depending upon the gait phase and the measured kinematic information.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: July 25, 2017
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Ming Wu, Brian D. Schmit, T. George Hornby
  • Patent number: 9700439
    Abstract: Apparatus and methods are provided for determining a locomotion mode that can be provided to a controller of a lower prosthesis limb in order to accurately control the prosthesis. One or more prosthesis sensors are provided that break a gait cycle down into a plurality of gait phases. EMG sensors provide signals to a processor that directs them to a gait phase specific classifier that is used to determine a particular locomotion mode for the wearer. With the locomotion mode accurately known, the prosthetic device can be accurately controlled.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: July 11, 2017
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Todd Kuiken, He Huang
  • Patent number: D788930
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: June 6, 2017
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Thomas George Hornby, John Gresko
  • Patent number: D797473
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: September 19, 2017
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Clive Wilkinson, Chester Nielsen, Amber Wernick, Joanne C. Smith
  • Patent number: D800479
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: October 24, 2017
    Assignee: Rehabilitation Institute of Chicago
    Inventors: Clive Wilkinson, Chester Nielsen, Amber Wernick, Joanne C. Smith