Patents Assigned to REPLICEL LIFE SCIENCES INC.
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Patent number: 11865324Abstract: The invention relates to an injection device which includes a handle and a guard which together enclose a movable cartridge which can contain liquid material to be injected, and further enclose a movable injector that includes a needle, the needle being attached to a housing where the housing is attached to the cartridge, the device also including a delivery mechanism whereby the needle is moved from a retracted to an extended position, and independently the volume of the chamber may be adjusted to expel the contents thereof through the needle and into a subject in need thereof. The injection device may be communicatively connected to a control unit so as to provide a dermal injection system.Type: GrantFiled: May 24, 2021Date of Patent: January 9, 2024Assignee: RepliCel Life Sciences Inc.Inventors: Rolf Hoffmann, Martin Hohlrieder
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Patent number: 11045612Abstract: The invention relates to an injection device which includes a handle and a guard which together enclose a movable cartridge which can contain liquid material to be injected, and further enclose a movable injector that includes a needle, the needle being attached to a housing where the housing is attached to the cartridge, the device also including a delivery mechanism whereby the needle is moved from a retracted to an extended position, and independently the volume of the chamber may be adjusted to expel the contents thereof through the needle and into a subject in need thereof. The injection device may be communicatively connected to a control unit so as to provide a dermal injection system.Type: GrantFiled: August 6, 2015Date of Patent: June 29, 2021Assignee: RepliCEL Life Sciences Inc.Inventors: Rolf Hoffmann, Martin Hohlrieder
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Patent number: 10500233Abstract: Briefly stated, the present invention provides compositions and methods for treating or preventing joint injuries utilizing hair follicle derived Non-Bulbar Dermal Sheath (“NDBS”) cells. Within one aspect of the invention methods are provided for isolating NBDS cells, comprising the steps of: (a) preparing vital hair; (b) cleaving the hair prepared in step (a) to remove the hair follicle bulb; (c) isolating Non-Bulbar Dermal Sheath tissue; and (d) cultivating the isolated Non-Bulbar Dermal sheath tissue to produce NBDS cells. Within one embodiment of the invention the vital hair is obtained by full skin biopsy from the occipital scalp of a subject.Type: GrantFiled: February 12, 2015Date of Patent: December 10, 2019Assignee: RepliCel Life Sciences Inc.Inventors: Rolf Hoffmann, Kevin John McElwee
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Patent number: 10272118Abstract: The present invention relates to compositions and methods utilizing hair follicle derived Non-Bulbar Dermal Sheath cells for use in the treatment or prevention of the tendon injuries.Type: GrantFiled: February 12, 2014Date of Patent: April 30, 2019Assignee: RepliCel Life Sciences Inc.Inventors: Rolf Hoffmann, Kevin John McElwee
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Publication number: 20170224935Abstract: The invention relates to an injection device which includes a handle and a guard which together enclose a movable cartridge which can contain liquid material to be injected, and further enclose a movable injector that includes a needle, the needle being attached to a housing where the housing is attached to the cartridge, the device also including a delivery mechanism whereby the needle is moved from a retracted to an extended position, and independently the volume of the chamber may be adjusted to expel the contents thereof through the needle and into a subject in need thereof. The injection device may be communicatively connected to a control unit so as to provide a dermal injection system.Type: ApplicationFiled: August 6, 2015Publication date: August 10, 2017Applicant: REPLICEL LIFE SCIENCES INC.Inventors: Rolf Hoffmann, Martin Hohlrieder
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Publication number: 20170173084Abstract: Briefly stated, the present invention provides compositions and methods for treating or preventing joint injuries utilizing hair follicle derived Non-Bulbar Dermal Sheath (“NDBS”) cells. Within one aspect of the invention methods are provided for isolating NBDS cells, comprising the steps of: (a) preparing vital hair; (b) cleaving the hair prepared in step (a) to remove the hair follicle bulb; (c) isolating Non-Bulbar Dermal Sheath tissue; and (d) cultivating the isolated Non-Bulbar Dermal sheath tissue to produce NBDS cells. Within one embodiment of the invention the vital hair is obtained by full skin biopsy from the occipital scalp of a subject.Type: ApplicationFiled: February 12, 2015Publication date: June 22, 2017Applicant: REPLICEL LIFE SCIENCES INC.Inventors: Rolf Hoffmann, Kevin John McElwee
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Publication number: 20170165299Abstract: The present invention relates to compositions and methods utilizing hair follicle derived Non-Bulbar Dermal Sheath cells for use in the treatment of dental-related conditions, including the treatment of gingivitis. Briefly stated, the present invention provides compositions and methods for treating or preventing a wide variety of conditions associated with the oral cavity, including for example, periodontal disease and a variety of diseases or injuries associated with the gingiva utilizing hair follicle derived Non-Bulbar Dermal Sheath (“NDBS”) cells. Within one aspect of the invention methods are provided for isolating NBDS cells, comprising the steps of: preparing vital hair and cleaving the hair.Type: ApplicationFiled: February 12, 2015Publication date: June 15, 2017Applicant: REPLICEL LIFE SCIENCES INC.Inventors: Rolf Hoffmann, Kevin John McElwee