Abstract: The present invention relates to compositions capable of promoting both the innate immune response as well as the adaptive immune response in a subject based on the jointly use of ApoA, interleukin 15 and the Sushi domain of the IL15 receptor alpha chain, as well as to the use of these compositions for the stimulation of the immune response in a patient and to therapeutic methods for the treatment of infectious and neoplastic diseases.
Type:
Grant
Filed:
December 10, 2010
Date of Patent:
July 8, 2014
Assignees:
Fundacion para la Investigacion Medica Aplicada, Research Center Borstel
Inventors:
Pedro Berraondo Lopez, Jessica Fioravanti, Jose Medina Echeverz, Ignacio Javier Melero Bermejo, Maria del Carmen Ochoa Nieto, Francisco de Asis Palazon Garcia, Silvia Bulfone-Paus, Erwin Hans Duitmann
Abstract: The present invention relates to compositions capable of promoting both the innate immune response as well as the adaptive immune response in a subject based on the jointly use of ApoA, interleukin 15 and the Sushi domain of the IL15 receptor alpha chain, as well as to the use of these compositions for the stimulation of the immune response in a patient and to therapeutic methods for the treatment of infectious and neoplastic diseases.
Type:
Application
Filed:
December 12, 2010
Publication date:
September 27, 2012
Applicants:
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA, RESEARCH CENTER BORSTEL
Inventors:
Pedro Berraondo Lopez, Jessica Fioravanti, Jose Medina Echeverz, Ignacio Javier Melero Bermejo, Maria del Carmen Ochoa Nieto, Francisco de Asis Palazon Garcia, Silvia Bulfone-Paus, Erwin Hans Duitmann