Patents Assigned to Research Development Corp. of Japan
-
Patent number: 6020127Abstract: The gene for the autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy has been mapped to a region of chromosome 5. The gene encodes a protein having homology with apoptosis inhibitor proteins of viruses so that the encoded protein has been labelled as a neuronal apoptosis inhibitor protein (NAIP). A deletion in the (NAIP) domain was identified in persons with Type I, II and III Spinal Muscular Atrophy (SMA) and not in the normal non-SMA population.Type: GrantFiled: June 20, 1997Date of Patent: February 1, 2000Assignees: The University of Ottawa, Research Development Corp. of JapanInventors: Alex E. MacKenzie, Robert G. Korneluk, Natalie Roy, Mani S. Mahadevan, Michael McLean, Joh-E Ikeda
-
Patent number: 5619174Abstract: A noise filter includes an annular magnetic core made of a soft magnetic alloy ribbon mainly made of Fe and containing B and at least one element selected from a group consisting of Ti, Zr, Hf, Nb, Ta, Mo and W, at least 50% of the soft magnetic alloy structure being composed of body-centered cubic structured fine grains having an average grain size of 30 nm or below, a casing for accommodating the magnetic core and having an insulating plate, a pair of coils separated from each other by the insulating plate, and an electronic circuit for connecting a core element made up of the magnetic core, the casing and the coils.Type: GrantFiled: July 29, 1994Date of Patent: April 8, 1997Assignees: Alps Electric Co., Ltd., Research Development Corp. of Japan, Tsuysohi MasumotoInventors: Youichi Kimura, Akihiro Makino, Tsuyoshi Masumoto, Akihisa Inoue
-
Patent number: 5532511Abstract: A semiconductor device includes a substrate crystal of a type for epitaxial growth thereon. The substrate crystal has a (111)A face and a (111)B face. Also provided are at least two semiconductor regions of different conductivity types deposited by way of epitaxial growth on the (111)A face of the substrate crystal according to metal organic chemical vapor deposition, thereby providing a structure having a source and a drain. A gate side includes the (111)B face of the substrate crystal. A gate insulating layer is deposited by way of epitaxial growth on the gate side according to molecular layer epitaxy. Alternatively, the at least two semiconductor regions may be deposited on the (111)B face of the substrate crystal according to molecular layer epitaxy, and the gate insulating layer may be deposited on the (111)A face of the substrate crystal according to metal organic chemical vapor deposition.Type: GrantFiled: March 23, 1995Date of Patent: July 2, 1996Assignees: Research Development Corp. of Japan, Jun-ichi Nishzawa, Zaidan Hojin Handotai Kenkyu ShinokaiInventors: Jun-ichi Nishizawa, Toru Kurabayashi
-
Patent number: 5479256Abstract: To derive spectrum information on chemical intermediates in photochemical reactions during transitional periods, a transient grating spectroscopy uses white light as the probe light in the pico-second region and monochromatic light in the microsecond region. According to the procedure, it is possible to analyze the photochemical reaction of thin films and interface layers as a function of time at a high precision.Type: GrantFiled: November 9, 1993Date of Patent: December 26, 1995Assignees: Research Development Corp. of Japan, Takashi ItoInventors: Naoto Tamai, Takashi Ito, Tsuyoshi Asahi, Hiroshi Masuhara
-
Patent number: 5432761Abstract: The invention provides a medium and a method suitable for magneto-optical and multiple recording.The medium includes alternate thin layers of a magnetic rare-earth metal and an electrically conductive material, and has "magnetic frozen state" at low temperature. The medium may be magnetized to different ferromagnetic states when heated to different temperatures by a controlled laser beam, under an external magnetic field. The different magnetic states permit of multiple recording.Type: GrantFiled: December 17, 1993Date of Patent: July 11, 1995Assignees: Research Development Corp. of Japan, Sanyo Electric Co., Ltd.Inventor: Atsushi Maeda
-
Patent number: 5412072Abstract: This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded. The hydrophilic first segments of the present invention include polyethylene glycol, polysaccharides, polyacrylamide, and so on. The hydrophobic segments being attached to a drug include polyaspartic acid, polyglutamic acid, polylysine, or derivatives thereof. Drugs to be attached to the hydrophobic segment include anti-cancer drugs, drugs for central nerve, drugs for circulatory organs, and so on.Type: GrantFiled: March 21, 1990Date of Patent: May 2, 1995Assignee: Research Development Corp. of JapanInventors: Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka, Noriko Yamada, Shohei Inoue, Masayuki Yokoyama
-
Patent number: 5354563Abstract: A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 .mu.m prepared by the steps of heating the medicine or hormone in a vacuum vessel at a temperature of 30.degree. C. higher than the boiling point and at a pressure between 0.01 Torr and 10 Torr to evaporate the medicine or hormone and condensing the medicine or hormone on a recovery plate to obtain the condensate.Type: GrantFiled: June 16, 1993Date of Patent: October 11, 1994Assignees: Research Development Corp. of Japan, Stanley Electric Co., Ltd.Inventor: Hideki Toyotama
-
Patent number: 5329353Abstract: A compact, high sensitive, multi-wavelength spectral analyzer capable of simultaneously obtaining a spectral distribution of extremely weak radiation such as bioluminescence, chemiluminescence, extremely weak fluorescence caused by excitation light, Raman scattered light, etc. with an extremely high luminosity and without wavelength scanning. The spectral analyzer comprises a spectroscope and a high sensitive one- or two-dimensional photodetector. The spectroscope includes an entrance slit, a collimator lens of high luminosity disposed such that a focal point of the collimator lens is coincident with the entrance slit to convert light emerging therefrom into parallel rays, a reflection diffraction grating that diffracts the parallel rays from the collimator lens to produce spectra, and an imaging lens that focuses the parallel rays diffracted by the reflection diffraction grating on an image plane thereof to form a spectral image. The photodetector is disposed on the image plane of the imaging lens.Type: GrantFiled: February 7, 1992Date of Patent: July 12, 1994Assignee: Research Development Corp. of JapanInventors: Tsutomu Ichimura, Toshiyuki Nogoshi, Fumio Inaba
-
Patent number: 5308976Abstract: Irradiating a plurality of laser beams onto different microparticles or different groups of microparticles, and trapping and/or manipulating these microparticles or groups of microparticles. This method permits manipulation of microparticles with a plurality of trapping laser beams not mutually interfering just as with two human hands. By coaxially introducing an excited laser beam, it is possible to induce chemical reactions for processing or assembling.Type: GrantFiled: May 29, 1992Date of Patent: May 3, 1994Assignee: Research Development Corp. of JapanInventors: Hiroaki Misawa, Keiji Sasaki, Nobura Kitamura
-
Patent number: 5296403Abstract: A semiconductor device comprises a vertical MIS-SIT which has a smaller source-to-drain distance for operation at ultra-high speed. The semiconductor device has a substrate crystal for epitaxial growth thereon, least two semiconductor regions of different conductivity types deposited by way of epitaxial growth on the substrate crystal according to either metal organic chemical vapor deposition (MO-CVD) or molecular layer epitaxy (MLE), thereby providing a source-drain structure, a gate side formed by etching the semiconductor regions of the source-drain structure, the gate side comprising either a (111)A face or a (111)B face, and a semiconductor region deposited as a gate by way of epitaxial growth on the gate side according to either MO-CVD or MLE.Type: GrantFiled: October 23, 1992Date of Patent: March 22, 1994Assignees: Research Development Corp. of Japan, Jun-ichi Nishizawa, Zaidan Hojin Handotai Kenkyu ShinkokaiInventors: Jun-ichi Nishizawa, Toru Kurabayashi
-
Patent number: 4977242Abstract: A cumulatable ultrafine polymer particle consisting of one molecular chain of the polymer is prepared by spreading a dilute solution of the polymer at the interface between the atmosphere and a subphase solution having a weak affinity for the polymer, and evaporating the spreading solvent or dissolving it into the subphase. A composite material comprising the polymer particles is produced by contacting the particles formed on the subphase solution with the surface of a substrate. The particles are cumulated on the substrate in a ratio of area occupied by the particles of at least 10%. The particles may be cumulated in multiple layers on the substrate.Type: GrantFiled: March 15, 1989Date of Patent: December 11, 1990Assignee: Research Development Corp. of JapanInventor: Jiro Kumaki
-
Patent number: 4913865Abstract: A method for manufacturing ultrafine particles of hardly water-soluble or water-insoluble organic compounds is disclosed herein, and the method includes heating and evaporating the organic compound in a vacuum vessel in which an inert gas is introduced in a desired pressure, then condensing and depositing the vaporized organic compound on a recovering means cooled, the resulting ultrafine particles exhibiting a high negative zeta potential sufficient to form a stable water dispersion thereof.Type: GrantFiled: May 22, 1986Date of Patent: April 3, 1990Assignees: Research Development Corp of Japan, Stanley Electric Co. Ltd.Inventor: Hideki Toyotama
-
Patent number: 4876077Abstract: A process for producing graphite includes heat treating, in an inert gas or in vacuo, at least one polymer selected from the group consisting of a polyphenyleneoxadiazole, polybenzothiazoles, a polybenzobisthiazole, a polybenzoxazole, a polybenzobisoxazole and a polythiazole, at a temperature of at least 1600.degree. C., preferably at least 2000.degree. C., for at least 30 minutes, preferably at least 60 minutes, to convert the polymer to a highly-graphitized graphite. The process produces almost perfect graphite in any shape, such as film-shaped for large-area graphite, fibrous or powdered.Type: GrantFiled: December 15, 1987Date of Patent: October 24, 1989Assignees: Research Development Corp. of Japan, Matsushita Elec. Industries Co. Ltd.Inventor: Mutsuaki Murakami
-
Patent number: 4818593Abstract: Unit layer polyheteroaromatic films of thickness less than 50 nm are obtained when an aldehyde monomer or aldehyde monomer precursor is spread onto an aqueous subphase containing an aromatic amine monomer, said aromatic amine monomer possessing amine or group VI heteroatom alcohols moieties in ortho (XH, NH.sub.2) pairs, where X is N or a group VI heteroatom. The resulting film can be transferred and built up as multilayer films on various substrates.Type: GrantFiled: February 3, 1987Date of Patent: April 4, 1989Assignee: Research Development Corp. of JapanInventor: Alan K. Engel
-
Patent number: 4785021Abstract: A method of adsorbing a substance such as an optically active substance, comprising contacting a solution of the substance in a solvent with an adsorbent consisting of a cross-linked polymer comprisingan optically active, synthetic poly(amino acid) represented by the general formula (I): ##STR1## wherein R stands for an organic group, R' stands for hydrogen or an alkyl group and n is an integer of at least 5, which may be protected at a terminal amino group anda carrier polymer supporting said synthetic poly(amino acid) thereon, said carrier polymer having affinity for said solvent. A method for producing the cross-linked polymer is also described.The adsorbent is especially useful for optical resolution of racemic mixtures.Type: GrantFiled: February 5, 1988Date of Patent: November 15, 1988Assignees: Research Development Corp. of Japan, Mitsubishi Kasei CorporationInventor: Hideaki Kiniwa
-
Patent number: 4749514Abstract: This invention relates to a graphite intercalation compound in the form of a film, which is obtained by intercalating a donor type, an acceptor type or a covalent type material between the layers of graphite film obtained by thermal treatment of poly(phenylene oxadiazole). The obtained intercalated graphite film has a large scale area and has an extremely improved stability compared with known graphite intercalation compounds.Type: GrantFiled: October 3, 1986Date of Patent: June 7, 1988Assignees: Research Development Corp. of Japan, Matsushita Elec. Industrial Co. Ltd.Inventors: Mutsuaki Murakami, Kazuhiro Watanabe, Susumu Yoshimura
-
Patent number: 4694044Abstract: A method of adsorbing a substance such as an optically active substance, comprising contacting a solution of the substance in a solvent with an adsorbent consisting of a cross-linked polymer comprising an optically active, synthetic poly(amino acid) represent by the general formula (I): ##STR1## wherein R stands for an organic group, R' stands for hydrogen or an alkyl group and n is an integer of at least 5, which may be protected at a terminal amino group and a carrier polymer supporting said synthetic poly(amino acid) thereon, said carrier polymer having affinity for said solvent. A method for producing the cross-linked polymer is also described.The adsorbent is especially useful for optical resolution of racemic mixtures.Type: GrantFiled: March 6, 1985Date of Patent: September 15, 1987Assignee: Research Development Corp. of JapanInventor: Hideaki Kiniwa
-
Patent number: 4687831Abstract: Antithrombogenic synthetic elastomer having repeat units comprising portion I which is a soft segment unit containing a polyether and portion II which is a hard segment unit: ##STR1## R is a straight-chain or branched-chain alkylene group containing 2 to 4 carbon atoms, R' is amide a urethane, an urea, n ranges up to 180, m is an integer of 1 to 20, l is an integer of 1 to 10, said polymer having a microdomain structure composed of soft and hard segments, the domains of which have an average size of 10 to 20 nm, and a molecular weight of about 80,000 to about 500,000.The polymer shows little adhesion of blood platelets thereto, little deformation of adhering blood platelets and an excellent antithrombogenic property. This polymer has excellent mechanical properties as an elastomer.Type: GrantFiled: April 16, 1986Date of Patent: August 18, 1987Assignee: Research Development Corp. of JapanInventors: Naoya Ogata, Kohei Sanui, Nobuhiko Yui, Kazuhiko Nojima, Kazunori Kataoka, Teruo Okano, Yasuhisa Sakurai
-
Patent number: 4681799Abstract: Novel ultrathin unit layers and built-up multilayers are obtained when a spreadable polyfunctional aldehyde or its precursor, particularly the alkyl Schiff base formed by its condensation with an alkyl amine, is spread on the surface of an aqueous subphase containing a diamine. The resulting polymeric imine unit layers were transferred and built up on subtrates which included quartz, aluminum and chrome-plated glass, and semiconductors.Type: GrantFiled: October 17, 1985Date of Patent: July 21, 1987Assignee: Research Development Corp. of JapanInventor: Alan K. Engel
-
Patent number: RE33022Abstract: A ferromagnetic amorphous alloy having a composition represented by (Co.sub.x Ni.sub.y Fe.sub.z).sub.a M.sub.b G.sub.c, wherein M is Cr, Mo and/or W, G is Zr, Hf and/or Ti and x,y,z and a, b, c are selected to meet the conditions of x=1-y-z, 0.ltoreq.y.ltoreq.0.2, 0.ltoreq.z.ltoreq.0.7, a=1-b-c, 0.ltoreq.b.ltoreq.0.05 and 0.05.ltoreq.c.ltoreq.0.2 This amorphous alloy has a superior magnetic characteristic and a high thermal stability.Type: GrantFiled: November 5, 1987Date of Patent: August 15, 1989Assignees: Hitachi, Ltd., Hitachi Metals, Ltd., Research Development Corp. of JapanInventors: Shinji Takayama, Yasuo Tsukuda, Kazuo Shiiki, Shigekazu Otomo, Mitsuhiro Kudo, Yasunobu Ogata, Yoshizo Sawada