Patents Assigned to Research Development Corporation of Japan
  • Patent number: 7198738
    Abstract: The present invention provides a cesium-lithium-borate crystal, which can be used as a high-performance wavelength converting crystal, having a chemical composition expressed as CsLiB6O10, and substituted cesium-lithium-borate crystals expressed by the following formula: Cs1?xLi1?yMx+yB6O10 or Cs2(1?z)Li2LzB12O20 (where, M is an alkali metal element, and L is an alkali earth metal element); a method for manufacturing same by heating and melting; and an optical apparatus using such crystals.
    Type: Grant
    Filed: December 23, 2005
    Date of Patent: April 3, 2007
    Assignee: Research Development Corporation of Japan
    Inventors: Takatomo Sasaki, Akio Hiraki, Yusuke Mori, Sadao Nakai
  • Patent number: 6797339
    Abstract: A method of forming a thin film on the surface of a substrate such as silicon, in which a gas cluster (which is a massive atomic or molecular group of a reactive substance taking the gaseous form at room temperature under atmospheric pressure) is formed and then ionized, and the cluster ions are then irradiated onto a substrate surface under an acceleration voltage to cause a reaction. It is possible to form a high quality ultra-thin film having a very smooth interface, without causing any damage to the substrate, even at room temperature.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: September 28, 2004
    Assignees: Research Development Corporation of Japan, Sanyo Electric Co., Ltd.
    Inventors: Makoto Akizuki, Mitsuaki Harada, Atsumasa Doi, Isao Yamada
  • Patent number: 6797334
    Abstract: In order to deopsit a high-grade and extra-thin film without causing damage to the substrate at a relatively low temperature, the present invention provides a method for forming a cluster which is a lumpy group of atoms or molecules of a reactive substance at the room temperature under the atmospheric pressure, irradiating electrons onto clusters, irradiating the resulting cluster ions onto a substrate surface by accelerating by an acceleration voltage, and at the same time or alternately, irradiating one or more component gases of the deposit film onto the substrate surface, thereby depositing a thin film on the substrate surface through reaction.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: September 28, 2004
    Assignees: Research Development Corporation of Japan, Sanyo Electric Co., Ltd.
    Inventors: Makoto Akizuki, Mitsuaki Harada, Satoru Ogasawara, Atsumasa Doi, Isao Yamada, Jiro Matsuo
  • Patent number: 6770330
    Abstract: A method of forming a particle film on a surface of a solid or liquid substrate involves contacting the substrate, in the presence of a gas, with a liquid medium containing a plurality of particles suspended therein. A liquid meniscus is thereby formed between the substrate and the gas. An edge of the liquid meniscus is moved relative to the substrate, so that said particles in the liquid medium form the particle film on the surface of the substrate.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: August 3, 2004
    Assignee: Research Development Corporation of Japan
    Inventors: Kuniaki Nagayama, Antony Stanckev Dimitrov
  • Patent number: 6485721
    Abstract: The present invention provides a biologically active substance secreting hybrid gel, which consists essentially of a biopolymeric gel and cells containing an expression vector with a gene encoding the biologically active substance to produce the substance. According to the present invention, it is possible to develop a gene therapy by skin transplantation allowing stable drug medication for a long time; alleviating pains of patients; and allowing fine adjustment of the dosage and control of genes externally without using retrovirusderived vector that tend to invoke the risk of mutation to wild types as in the conventional prescription.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: November 26, 2002
    Assignees: Research Development Corporation of Japan, Genentech, Inc.
    Inventors: Susumu Yoshida, R. Andrew Cuthbertson, Katsutoshi Yoshizato
  • Patent number: 6464793
    Abstract: A substrate is heated in a crystal growth vessel evacuated to a ultrahigh vacuum, and gases containing component elements of a crystal to be grown on the substrate are introduced into the vessel under predetermined conditions to cause successive epitaxial growth of single molecular layers, the number of growth cycles being automatically controlled. A mass analyzer is disposed opposite to the substrate in the vessel so that the progress of crystal growth can be incessantly traced and evaluated for each of the molecular layers. An etchant gas introduction nozzle extends into the vessel to make etching treatment of the surface of the substrate in the evacuated vessel prior to the crystal growth.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: October 15, 2002
    Assignees: Research Development Corporation of Japan
    Inventors: Junichi Nishizawa, Hitoshi Abe
  • Patent number: 6429011
    Abstract: The gene for autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy has been mapped to a region of chromosome 5. The gene encodes a protein having homology with apoptosis inhibitor proteins of viruses so that the encoded protein has been labelled as a neuronal apoptosis inhibitor protein (NAIP). A deletion in the (NAIP) domain was identified in persons with Type I, II and III Spinal Muscular Atrophy (SMA) and not in the normal non-SMA population.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: August 6, 2002
    Assignees: University of Ottawa, Research Development Corporation of Japan
    Inventors: Alex E. MacKenzie, Robert G. Korneluk, Natalie Roy, Mani S. Mahadevan, Michael McLean, Joh-E Ikeda
  • Patent number: 6333151
    Abstract: The present invention provides nucleic acid markers for rice blast resistance genes Pi-ta and Pi-ta2, which hybridize with any RFLP probes isolated from rice genomic DNA and are located within a distance of 2.0 cM from rice blast resistance genes Pi-ta or Pi-ta2. According to the present invention, it becomes possible to easily identify rice blast resistance genes and related genes from rice cultivars containing Pi-ta or Pi-ta2, thus promoting development and breeding of superior cultivars. It becomes also possible to easily carry out a resistance test of rice. This will open up way to create new resistance genes.
    Type: Grant
    Filed: July 29, 1994
    Date of Patent: December 25, 2001
    Assignees: Research Development Corporation of Japan, National Institute Agrobiological Resources Ministry of Agriculture Forestry and Fisheries
    Inventors: Shinji Kawasaki, Masaya Satoh, Naoki Katsura, Akira Saitoh, Ikuo Andoh
  • Patent number: 6296784
    Abstract: The present invention provides a cesium-lithium-borate crystal, which can be used as a high-performance wavelength converting crystal, having a chemical composition expressed as CsLiB6O10, and substituted cesium-lithium-borate crystals expressed by the following formula: Cs1−xLi1−yMx+yB6O10 or Cs2(1−z)Li2LzB12O20 (where, M is an alkali metal element, and L is an alkali earth metal element); a method for manufacturing same by heating and melting; and an optical apparatus using such crystals
    Type: Grant
    Filed: July 17, 1995
    Date of Patent: October 2, 2001
    Assignee: Research Development Corporation of Japan
    Inventors: Takatomo Sasaki, Akio Hiraki, Yusuke Mori, Sadao Nakai
  • Patent number: 6086724
    Abstract: Particulates are trapped by laser beam and brought into contact with electrodes to electrochemically and spectroscopically measure the reaction process thereof.Precise measurement of the process of chemical reactions such as electrochemical and photochemical ones of a single particulate is made possible.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: July 11, 2000
    Assignee: Research Development Corporation of Japan
    Inventors: Kiyoharu Nakatani, Hiroaki Misawa, Noboru Kitamura, Tatsuya Uchida
  • Patent number: 6033783
    Abstract: An ultrafine Al particle consists of an Al multiply twinned particle. The Al multiply twinned particle has a decahedron structure surrounded by {111} planes. The Al multiply twinned decahedral particle has a diameter of 10 to 30 nm. Such an ultrafine Al particle consisting of the Al multiply twinned decahedral particle is obtained as follows. A metastable Al oxide particle is placed on an amorphous carbon substrate having the reduction effect. Then the electron beam is irradiated to the metastable Al oxide particle placed on the amorphous carbon substrate in the vacuum atmosphere. From the metastable Al oxide particle, Al atoms or Al clusters are emitted and adsorbed to the substrate. By adjusting the electron beam intensity so that the ultrafine Al particle in the above procedure has a diameter from 10 to 30 nm, the Al multiply twinned particle having a decahedron is obtained.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: March 7, 2000
    Assignees: Research Development Corporation of Japan, Kabushiki Kaisha Toshiba
    Inventors: Shun-ichiro Tanaka, BingShe Xu
  • Patent number: 6020131
    Abstract: The present invention has an object to provide an easy method for detecting a nucleic acid polymer in aqueous phase.The present invention provides a method for detecting the amount of nucleic acid polymer, which comprises the steps of modifying an intercalator to be amphiphilic by using a hydrophobic group, spreading the amphiphilic intercalator on an aqueous solution containing a nucleic acid polymer to form a monolayer of said nucleic acid polymer and said amphiphilic intercalator at the gas-water interface, and measuring surface pressures per unit area of said monolayer.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: February 1, 2000
    Assignee: Research Development Corporation of Japan
    Inventors: Kunihara Ijiro, Masatsugu Shimomura
  • Patent number: 6004810
    Abstract: The present invention provides liver parenchymal cells having a clonal growth ability, which possesses at least one of the cell biological properties such as: presence of peroxysome; being positive to hepatocyte-markers; being partially positive to neoplastic hepatocyte-markers or immature hepatocyte-markers; being positive to antibodies against the surface antigens of ovall cells; and being partially positive to bile duct cell-markers. The present invention also provides a method for obtaining such cells and a method for subculturing such cells.With the liver parenchymal cells above, it will be possible to research in detail the process of development and differentiation, the mechanisms of growth and functional expression of hepatic cells, and to open up a new way to clalification of mechanisms or hepatoma and various other diseases and to development of therapeutic method against these disseases.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: December 21, 1999
    Assignee: Research Development Corporation of Japan
    Inventors: Chise Tateno, Katsutoshi Yoshizato
  • Patent number: 5994899
    Abstract: A magneto-impedance element includes an amorphous wire having a spiral magnetic anisotropy. A dc-biased alternating current is supplied to the amorphous wire, whereby a voltage is produced between both ends of the amorphous wire. The amplitude of the voltage varies asymmetrically with a variation in an externally applied magnetic field. The magneto-impedance element is compact, and has a high sensitivity and a high response speed.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: November 30, 1999
    Assignee: Research Development Corporation of Japan
    Inventor: Kaneo Mohri
  • Patent number: 5990235
    Abstract: A chemically bonded olefin block copolymer consists essentially of chemically bonded polypropylene and poly(ethylene-co-propylene). The block copolymer is obtained by a process of (1) introducing a Ziegler polymerization catalyst based on titanium and propylene to a first polymerization zone (a) and polymerizing the propylene in the polymerization zone (a) for a period of 0.01 to 0.130 seconds and withdrawing an effluent stream of polypropylene, catalyst, solvent and unreacted propylene therefrom; (2) introducing the effluent stream to a second polymerization zone (b) together with ethylene dissolved in a solvent and carrying out a polymerization reaction in the second polymerization zone (b) for a period of 0.01 to 0.130 seconds; and (3) recovering the block copolymer.
    Type: Grant
    Filed: May 28, 1997
    Date of Patent: November 23, 1999
    Assignee: Research Development Corporation of Japan
    Inventor: Minoru Terano
  • Patent number: 5981316
    Abstract: An insulated lattice is prepared with a plurality of lattice oriented atoms to create a substantially planar surface having a lattice arrangement. Any unsatisfied chemical bonds are terminated along the substantially planar surface by placing atoms at the site of the unsatisfied chemical bonds to terminate the unsatisfied chemical bonds and insulate the surface to form an insulated lattice platform. Atoms are placed at predetermined locations on the insulated lattice platform to form a first atomic chain which behaves as one of a conductor, a semiconductor and an insulator. A second chain of atoms is also placed at predetermined locations on the insulated lattice platform so that the second chain behaves as another of a conductor, a semiconductor and an insulator. These placements are made such that the second chain of atoms is electrically coupled to the first chain of atoms, and the second chain of atoms behaves differently than the first chain of atoms.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: November 9, 1999
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Research Development Corporation of Japan
    Inventors: Toshishige Yamada, Yoshihiro Takiguchi, Dehuan Huang, Yoshihisa Yamamoto
  • Patent number: 5955334
    Abstract: A process is disclosed for culturing microorganisms or cells isolated from a multicellular organism while exposing the microorganism or cells to sound waves of 5 to 100 kHz. This procedure effects the proliferation and the expression of functions of the cells so exposed. An apparatus for culturing the cells according to this process is also disclosed.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: September 21, 1999
    Assignee: Research Development Corporation of Japan
    Inventors: Michio Matsuhashi, Sugio Otani, Tomohiko Kaneko
  • Patent number: 5945176
    Abstract: An onion-like graphite 2 is produced by irradiating an electron beam to an amorphous carbon 3 under an active aluminum nanoparticle 1. By further irradiating the electron beam to the onion-like graphite 2 to intercalate aluminum atoms constituting the aluminum nanoparticle 1 in a space between (001) plane and (002) plane of the onion-like graphite 2 having a layer structure, an intercalation compound 4 is produced. Or, after the aluminum nanoparticles were driven and disposed on the onion-like graphite by electron beam, or the like, by irradiating the electron beam to intercalate aluminum atoms in the space between the (001) plane and the (002) plane of the onion-like graphite having a layer structure, the intercalation compound is produced.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: August 31, 1999
    Assignees: Research Development Corporation of Japan, Shun-ichiro Tanaka
    Inventors: BingShe Xu, Shun-ichiro Tanaka
  • Patent number: 5936346
    Abstract: An electroluminescence element provided with a luminescent layer sandwiched between two electrodes on an insulating substrate. The luminescent layer is composed of zinc sulfide with a fluoride or a luminescent center element added, wherein the X-ray diffraction spectrum thereof has only a single peak at an X-ray diffraction angle from the luminescent layer, ranging from 25.degree. to 30.degree. according to a thin film X-ray diffraction measurement method using Cu-Kd radiation, and no other peaks of the X-ray diffraction spectrum exist at an X-ray diffraction angle of 27.degree..
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: August 10, 1999
    Assignees: Nippondenso Co., Ltd., Research Development Corporation of Japan
    Inventors: Hajime Ishihara, Yutaka Hattori, Masayuki Katayama, Nobuei Ito, Tadashi Hattori
  • Patent number: RE37799
    Abstract: A method and apparatus for continuously spot-welding galvanized steel sheets overlapped to be bonded by way of a spot welding machine having a pair of electrodes. The galvanized steel sheets clamp a resistance increasing material including a spacer to ensure a gap between the sheets. Bonding surfaces of the galvanized steel sheets partly contact each other when the pair of electrodes pressurize the galvanized steel sheets such that a part of the gap is retained around the spacer between the bonding surfaces. The retained gap has a size in which zinc melted or vapored when a weld current flows between the electrodes can escape through a weld section of the galvanized steel sheets to outside. The method comprises the step of recording an inter-electrode resistance for each spot when the continuous spot welding is executed by the pair of electrodes.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: July 23, 2002
    Assignees: Kabushiki Kaisha Toyoda Jidoshokki Seisakusho, Research Development Corporation of Japan
    Inventors: Toichi Watanabe, Tadashi Sofue