Abstract: This invention provides a composition comprising the compound having the structure: ethyl 2-[19F]F-4-nitrobenzoate, and at least one acceptable carrier. This invention also provides a method of detecting the presence of or location of bacteria cells in a subject which comprises determining if an amount of the compound or determining where an amount of the compound having the structure: is present in the subject at a period of time after administration of the compound or salt thereof to the subject, thereby detecting the presence of or location of the bacteria cells based on the amount of the compound determined to be present in the subject or detecting the location of the bacteria cells based on the location of the compound determined to be present in the subject.

Abstract: A photonic structure can include in one aspect one or more waveguides formed by patterning of waveguiding material adapted to propagate light energy. Such waveguiding material may include one or more of silicon (single-, poly-, or non-crystalline) and silicon nitride.

Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.

Abstract: This disclosure introduces a mapping for creating good Doppler detection capable radar codes. The mapping transfers an existing digital radar code to the warped frequency domain by expressing the code elements as magnitudes and phases of selected frequencies. These frequencies are equispaced in the warped frequency domain to preserve the code's sidelobes after mapping. The frequency warping function may convert the multiplicative Doppler shift into an additive shift of the code pattern in the warped frequency domain, which allows Doppler shift detection.

Abstract: A method for treating wastewater, comprising: (i) injecting a hydrate-forming gas (e.g., propane) into the wastewater under conditions of elevated pressure and reduced temperature to form a solid hydrate composed of the hydrate-forming gas and water from the wastewater; and (ii) separating the solid hydrate from the wastewater to result in removal of water from the wastewater, thereby resulting in partially dewatered wastewater, and optionally, (iii) lowering the pressure and/or raising the temperature of the solid hydrate to decompose the solid hydrate into reformed hydrate-forming gas and reformed water, and further optionally, recycling the reformed hydrate-forming gas for use in step (i) and/or capturing the reformed water from step (iii) and further decontaminating until suitable for release into waterway or for use in a process. The invention is also directed to an apparatus for practicing the method described above.

Abstract: The current disclosure provides methods for detecting and analyzing KRT4 and KRT17 expression in a sample obtained from a test subject. The current disclosure pertains to methods and kits for identifying a mammalian subject with cervical cancer or non-cancerous lesions of the cervix. The current disclosure further provides methods and kits for determining the likelihood of survival or treatment outcome of a subject having cervical cancer by determining the expression level of KRT17 in a sample.

Abstract: The present disclosure is directed to devices, systems and methods that include a stage and an actuator configured to transmit a orthogonal force to the stage, wherein the actuator is configured to receive a plurality of orthogonal acceleration signals, wherein the orthogonal acceleration signals comprise an actuator frequency signal and an actuator magnitude signal.

Abstract: The current disclosure provides methods for detecting and analyzing KRT17 expression in a sample obtained from a subject. The current disclosure also pertains to methods and kits for identifying a mammalian subject with head and neck squamous cell carcinoma. The current disclosure further provides methods and kits for determining the likelihood of survival of a subject having head and neck squamous cell carcinoma.

Abstract: Detection of synthetic content in portrait videos, e.g., deep fakes, is achieved. Detectors blindly utilizing deep learning are not effective in catching fake content, as generative models produce realistic results. However, biological signals hidden in portrait videos which are neither spatially nor temporally preserved in fake content, can be used as implicit descriptors of authenticity. 99.39% accuracy in pairwise separation is achieved. A generalized classifier for fake content is formulated by analyzing signal transformations and corresponding feature sets. Signal maps are generated, and a CNN employed to improve the classifier for detecting synthetic content. Evaluation on several datasets produced superior detection rates against baselines, independent of the source generator, or properties of available fake content.

Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.

Abstract: Provided are methods for determining a presence of an intracranial aneurysm in a subject suspected of having an intracranial aneurysm or at risk for developing an intracranial aneurysm, or a subject in need of aneurysm monitoring. The method involves analyzing a biological sample from the subject for expression of a combination of biomarkers that provide a signature of an aneurism.

Abstract: A system and method for detecting a suspicious object, including a wireless signal transmitter with first and second transmitter antennas, a first wireless signal receiver on an opposite side of the object from the transmitter having first and second receiver antennas, and a second wireless signal receiver on a same side of the object as the transmitter having a third receiver antenna. The transmitter may emit wireless signals from each of the transmitter antennas. The signals emitted by the first transmitter antenna may be received at the first and second receiver antennas. The signals emitted by both transmitter antennas may be received at the third receiver antenna. The object's material type may be determined based on channel state information of the wireless signals received at first receiver. A size of the object may be determined based on channel state information of the wireless signals received at the second receiver.

Abstract: A capacitor may be configured with a dielectric laminate disposed on ordered or non-ordered structures. Materials for the dielectric laminate have high dielectric constant and reduce leakage current to increase breakdown voltage of the device. These materials may include titanium dioxide (TiO2) and silicon dioxide (SiO2). In one implementation, the capacitor may reside on a substrate. The capacitor may have structure (e.g., nano-tubes, nano-holes, etc;) disposed on the substrate having a surface area greater than the surface area of the substrate and a laminate conformally coating the structure, the laminate comprising a first layer and a second layer with materials that configure the capacitor with an energy density of at least 60 Wh/Kg.

Abstract: The present disclosure provides modified short-interfering ribosomal nucleic acid compositions that have one or more uracil bases replaced a 5-fluorouracil molecule. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within an siRNA nucleotide sequence with a 5-fluorouracil increases the ability of the short interfering RNA to inhibit cancer progression and tumorigenesis when compared to known cancer therapeutics. As such, the present disclosure provides various short-interfering nucleic acid compositions having 5-fluorouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.

Abstract: Provided are multiply functional charged telodendrimers. The telodendrimers can be used for protein encapsulation and delivery. The charged telodendrimers may have one or more crosslinking groups (e.g., boronic acid/catechol reversible crosslinking groups). The telodendrimers can aggregate to form nanoparticles. Cargo such as combinations of proteins and other materials may be sequestered in the core of the nanoparticles via non-covalent or covalent interactions with the telodendrimers. Such nanoparticles may be used in protein delivery applications.

Abstract: The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A stimulus is displayed in a visual field on a stimulus side (e.g., right or left) of a subject. An input is received from an input side of the subject. Where the input side is contralateral to the first stimulus side, a crossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. Where the input side is ipsilateral to the stimulus side, an uncrossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. A crossed-uncrossed difference time can be determined as a difference between the crossed reaction time and the uncrossed reaction time. The crossed reaction time, the uncrossed reaction time, and/or the crossed-uncrossed difference time can be used to determine a severity of Traumatic Brain Injury of the subject.

Abstract: The invention provides anelastase inhibitor for use in the promotion of muscle regeneration in the treatment of a myopathy, as well as a method for promoting muscle regeneration in a subject with a myopathy, the method comprising providing the subject with a therapeutically effective amount of an elastase inhibitor. Further provided is a pharmaceutical composition comprising anelastase inhibitor for use in the promotion of muscle regeneration in the treatment of a myopathy. Elastase inhibitors may have a protective effect on muscle progenitor cells and their regenerative potential, which aids muscle cell regeneration. By protecting regenerative potential of muscle progenitor cells, elastase inhibitors enable or enhance the gown of new or existing muscle fibres.

Abstract: A composite structure is disclosed comprising a neutron-absorbing metal hydride phase contained within a matrix having a density of greater than 95%. In various embodiments the metal hydride is a hydride of one or more of the following: Gadolinium, Hafnium, Europium, Samarium. The composite structure is utile as a shield for fusion or fission reactors.

Abstract: The disclosure relates to a device and positron emission tomography (PET) scanner for acquiring a PET image and a system for generating the PET image. The disclosure describes a device that may have one or more moveable portions. The device may comprise an upper portion and a lower portion. The upper portion and lower portion define a cavity for a patient. At least one of the upper portion or the lower potion may be movable. The upper and lower portions may comprise a cap and wings, respectively, At least one of the caps and/or wings may comprise one or more detection modules. The wings may also move with respect to a corresponding cap.