Patents Assigned to Rhode Island Council on Postsecondary Education (Statutory Successor to Rhode Island Board of Governors for Higher Education)
  • Environmentally sensitive compositions and methods of use thereof
    Patent number: 9814781
    Abstract: An environmentally sensitive membrane binding polypeptide, pH (low)-sensitive membrane peptide (pHLIP) has improved insertion kinetics balanced with solubility to selectively target acidic tissues.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: November 14, 2017
    Assignees: Rhode Island Council on Postsecondary Education (Statutory Successor to Rhode Island Board of Governors for Higher Education), Yale University
    Inventors: Yana K. Reshetnyak, Oleg A. Andreev, Donald M. Engelman
  • Liposome structures and methods of use thereof
    Patent number: 9750693
    Abstract: The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: September 5, 2017
    Assignees: Rhode Island Council on Postsecondary Education (Statutory Successor to Rhode Island Board of Governors for Higher Education), Yale University
    Inventors: Yana K. Reshetnyak, Oleg A. Andreev, Donald M. Engelman