Abstract: A vaccine effective against Marek's disease virus (MDV) comprises (a) an MDV attenuated by virtue of being TK- or (b) a host expressing an MDV antigen, namely the respective MDV homologues of the HSV gB, gC, gD or gH glycoproteins (or antigenic parts thereof) or the respective MDV homologues of the HSV-1 immediate early genes IE-68 or IE-175. The host may be a herpes virus of turkeys (HVT), more particularly HVT in which the MDV antigen is inserted in the HVT homologue of the HSV gC gene, the ribonucleotide reductase (large subunit) gene or the thymidine kinase (TK) gene.

Abstract: Aqueous pharmaceutical compositions containing up to about 40% spectinomycin, prepared by the reaction of the ketone hydrate of spectinomycin with boric acid to form the boron compound, and with a base such as sodium hydroxide to form the stable salt of the compound.

Abstract: Process for preparing microspheres for the prolonged release of the LHRH hormone and of its analogues, the hormone being dispersed in a water-insoluble polymer or copolymer matrix, the solvent evaporation process is characterized by the use of a pair of organic solvents of which one makes it possible more specifically to obtain a homogeneous suspension of the hormone in the pulverulent state by simply stirring and of which the other is slightly water-miscible so as to allow more specifically the microdispersion of the organic phase in the aqueous phase in which the hardening of the microspheres is performed. This process leads to the preparation of LHRH-containing microspheres which are noteworthy for their purity, especially to microspheres with complex matrices, as well as to formulations comprising at least two types of microspheres.

Abstract: Selfadhesive label intended to be placed on a support and equipped with at least one detachable part and with one fixed part intended to remain on the support when the detachable part is detached, as well as with a tab projecting from the label and not adhering to the support, which comprises a detachment strip which extends between the fixed part and the detachable part or parts and which is designed in order, when it comes into action, to entrain with it, at least partially, the detachable part or parts, and then, optionally, to be separated therefrom, and wherein the detachment strip is designed in order to be held on the support when the label is affixed to the latter and has the projecting tab.

Abstract: Method for the culture of Babesia divergens, characterized in that the Babesia strain is maintained under culture in a culture medium free from serous protein but containing lipoproteins and red blood corpuscles, and a method for preparing exoantigens and a vaccine containing these antigens.

Abstract: A device for implanting an object, such as a hormone pellet or an electronic transponder beneath the skin of an animal, includes a hollow needle (1) with an actuating rod (11) slidable therein, a cover (2) movable relative to the needle to enable at least the sharp end of the needle to be shrouded, and a locking mechanism in the form of an abutment (10) movable into a rebate (6), from which it cannot then return. The needle (11) may be mounted at one end of a body (4) which incorporates the locking rebate (6).

Abstract: The recombinant virus chosen from the turkey herpesvirus(HVT), Aujeszky's disease virus (PRV), infectious bovine rhinotracheitis virus (BHV) feline infectious rhinotracheitis virus (FHV), equine rhinopneumonia virus (EHV), canine herpesvirus (CHV), duck herpesvirus, human simplex herpesvirus (HSV), varicella virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), comprises at least one heterologous gene, coding particularily for a viral, bacterial or parasitic immunogen inserted in the region of the genome of the said virus corresponding to the gene of the small sub-unit RR2 of ribonucleotide reductase so that it may be expressed. The method for preparing a virus of this type involves inserting the heterlogous gene into the said region of the genome, particularly after partial or total deletion of this region. The recombiant virus obtained may be used particularly for preparing living vaccines. The small sub-unit of the ribonucleotide reductase of the turkey herpesvirus (HVT) has been sequenced.

Abstract: A peptide fraction inducing the formation of antibodies which protect against the bovine leukemia virus (BLV), wherein it includes a peptide sequence which reproduces all or part of the sequence of the glycoprotein envelope gp51 fragment of the BLV virus which bears at least one of the epitopes (F, G, H) responsible for the biological activity of the virus. This fraction may be the fragment itself or a synthetic peptide. Application is made to the preparation or search for antibodies, to diagnosis and to the preparation of vaccines.

Abstract: In the method of identification and preparation of general and/or specific probes for varieties of Pestivirus, a length of approximately 110 to 115 bases, towards the 5' end on the Pestivirus genome in the non-coding region corresponding to the region situated between bases 200 and 310 of the genome of the BVD Osloss virus, is amplified by means of converging primers in a polymerase chain reactions, the amplified length is sequenced and, by comparison with similar previously sequenced lengths of other varieties of Pestivirus, the homologous and/or specific oligonucleotidic sequences of the probes are identified.

Abstract: The invention concerns a method for the culture of the infectious rhinotracheitis virus, TRT/SHS in the turkey that is also responsible for disorders in other bird species such as the infectious big head syndrome (or swollen head syndrome) in the chicken and guinea fowl.According to the invention, samples are taken from sick animals that are inoculated on cell cultures consisting of a continuous line of monkey kidney cells.A large quantity of the virus is obtained. This can be used as an antigen in the production of a vaccine that can be equally used for the immunization of all bird species.The invention also applies to the production of vaccines from viral strains obtained by means of this method.

Abstract: In a process for the culture of Babesia canis, erythrocytes infected by the Babesia canis parasite are incubated in a culture medium suitable for the survival of the erythrocytes and for breeding of the parasites, in the presence of a homologous serum, in the substantially static state, in a normal atmosphere, first of all at a high temperature of 34.degree. to 38.degree. C., then a low temperature, more especially between 0.degree. and 10.degree. C., this cycle being able to be reproduced. The supernatant product is collected which is centrifugated and filtered. A vaccine is prepared against pyroplasmosis in dogs from this floating medium.