Abstract: A cleansing and disinfecting composition comprising an alkaline per-salt and a positively charged phase-transfer agent. The composition preferably also contains a surfactant. The alkaline per-salt is an alkaline water-soluble salt having hydrogen peroxide of crystallization. The positively charged phase-transfer agent is preferably a quaternary ammonium salt. The composition may be formulated as a cream, aa bulk powder, a solution or tablets. It may also be incorporated in wipes, sponges and brushes. The compositions of this invention find utility in health care, as disinfectants in surgical applications, and as decontaminating agents. Specific uses include skin cleansing and disinfecting, treatment for exposure to toxic plants such as poison ivy, treatment for exposure to industrial and agricultural chemicals such as herbicides and pesticides, and cleansing and disinfecting surfaces and sensitive equipment.