Abstract: The present disclosure relates to a modular transport plane with a plurality of transport module units, each transport module unit comprising an actuator assembly with a back iron, and with an infrastructure system arranged below the transport module units and supporting the transport module units on a floor, characterized in that the transport module units are floatingly connected to the infrastructure system to allow a relative horizontal movement between the transport module units and the infrastructure system, wherein neighboring transport module units are connected via the back irons for a horizontal force transmission between neighboring transport module units in response to a relative horizontal movement between neighboring transport module units.

Abstract: A support element for a modular transport plane with a plurality of transport module units each comprising a driving surface assembly is presented. The support element has an upper support surface supporting the driving surface assemblies of at least two neighboring transport module units. The upper support surface has driving surface assembly interfaces engaged with complementary interfaces of the supported driving surface assemblies. The support element comprises a lower part having a mounting structure and an upper part having the upper support surface. The upper part connects lengthwise to the lower part via a connection structure. The connection structure restrains a relative movement between the lower part and the upper part in the longitudinal direction of the support element and allows a limited relative movement between the lower part and the upper part in a plane perpendicular to the longitudinal direction of the support element.

Abstract: The present disclosure relates to a method to re-identify a carrier on a laboratory transport system after a system failure. The carrier is associated with an identity and is configured to move over a transport plane of the laboratory transport system. The laboratory transport system comprises a monitoring system configured to monitor motion positions of the carrier on the transport plane when the laboratory transport system is activated. After a system failure, the identity dissociates from the carrier and the carrier keeps moving on the transport plane. After reactivation of the laboratory transport system, a predicted position of the identity is compared to an actual position of the carrier by a control unit of the laboratory transport system. The control unit assigns the identity to the carrier if the predicted position of the identity matches with the actual position of the carrier.

Abstract: A method for determining system resistance of at least one power supply of a handheld medical device, the method including: a) generating at least one excitation voltage signal, wherein the excitation voltage signal comprises at least one direct current (DC) voltage signal, wherein the excitation voltage signal has a fast transition DC flank of 20 ns or less; b) applying the excitation voltage signal to at least one reference resistor having a predetermined or pre-defined resistance value, wherein the reference resistor is arranged in series with the power supply; c) measuring a response signal of the power supply; d) determining a signal flank from the response signal and determining an ohmic signal portion from one or both of shape and height of the signal flank; and e) determining the system resistance of the power supply from the ohmic signal portion.

Abstract: A laboratory system and a method for separating interfering substances contained in test samples is presented. The laboratory system comprises separation vessels comprising solid surfaces and capturing molecules which are immobilized on the solid surfaces. The capturing molecules of the separation vessels are configured to bind interfering substances of laboratory tests of different analytical methods.

Abstract: A handheld diagnostic device, specifically for point-of-care applications. The handheld diagnostic device comprises at least one diagnostic measurement unit configured for performing at least one diagnostic measurement, the diagnostic measurement unit comprising at least one test element port for determining at least one diagnostic parameter of at least one patient by using at least one diagnostic test element; at least one camera configured for capturing at least one image of at least one wound of the patient; and at least one control unit, the control unit being configured for controlling the diagnostic measurement and for controlling the capturing of the image of the wound, wherein the control unit is further configured for storing at least one measurement result of the diagnostic measurement and the at least one image in at least one database record of the patient. A diagnostic system and a diagnostic method are further disclosed.

Abstract: The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.

Abstract: A method for processing data of an analytical instrument for analyzing biological samples is presented. The method comprises receiving instrument data from the analytical instrument at a data processing module communicatively connected with the analytical instrument, generating metadata from the received instrument data at the data processing module, applying a first encryption to the instrument data at the data processing module, applying a second encryption to the generated metadata at the data processing module, and transmitting the encrypted metadata and encrypted instrument data to a remote server. The remote server and the data processing module are communicatively connected. The method also comprises removing the second encryption from the metadata at the remote server and forwarding the instrument data encrypted by the first encryption from the remote server to a management system of the analytical instrument.

Abstract: A method to optimize analyzer use in a laboratory having a plurality of analyzers based on laboratory workload is presented. The method comprises determining current laboratory workload, calculating workload capability of the plurality of analyzers minus one analyzer if the current laboratory workload is below a threshold criteria and if there are two or more analyzers in the plurality of analyzers, masking one of the plurality of analyzers if the current workload is met by the plurality of analyzers minus one analyzer, proceeding with current workload, and repeating the above steps until the current laboratory workload has been completed.

Abstract: The present disclosure is directed at an antibody conjugate having an antibody and a tag, wherein one or more element(s) present in the antibody exhibit an isotope ratio which differs from the naturally occurring isotope ratio of the one or more element(s), wherein the amount of the isotope which is less-common in nature, is increased to at least 4% of the atoms of the respective element in the antibody, as well as uses thereof.

Abstract: A monitoring device for monitoring an electric motor, specifically of a laboratory system, is disclosed. The monitoring device comprises at least one receiving unit configured for receiving information on at least one amount of acceleration energy required for accelerating the electric motor from at least one first motion state to at least one second motion state and at least one evaluation unit configured for evaluating the information on the amount of acceleration energy and for determining at least one item of information on a wearing status of the electric motor. The acceleration energy comprises an acceleration energy which is at least one of dissipated, recuperated or released when decelerating the electric motor from a rotating motion state to a stationary state. Further, a laboratory system, a method of monitoring an electric motor, a method of operating a laboratory system, computer programs and computer-readable storage media are disclosed.

Abstract: A laboratory system, comprising: at least one rack comprising retainers, wherein the rack is adapted to carry laboratory sample containers inserted in the retainers, a handling device, wherein the handling device is adapted to insert sample containers in the retainers or remove containers from the retainers being placed at a processing position depending on location information indicating the location of the rack being placed at the processing position relative to the handling device, a plurality of teaching devices, wherein a respective teaching device is insertable into a retainer of the rack, and wherein at least two teaching devices are inserted into a corresponding retainer of the rack being placed at the processing position, and a location information calculating device, wherein the calculating device is adapted to calculate the location information of the rack being placed at the processing position depending on the location of the at least two teaching devices.

Abstract: A method of monitoring detection of an analyte in a liquid sample using a measuring cell, the measuring cell comprising a working electrode for excitation of electrochemiluminescence in the liquid sample, an optical detector for detecting the excited electrochemiluminescence, the excitation and detection being performed in an measurement cycle, the measurement cycle comprising transporting the liquid sample via a transport path to the working electrode using a support liquid, the method comprising: coupling light of a light source into the transport path during part of the measurement cycle, the transport path forming a light guide between the light source and the optical detector, detecting the coupled light by the optical detector, analyzing the detected light for a gas bubble in the transport path, providing a measurement state if the result of the analysis deviates from a target state regarding the presence of a gas bubble in the transport path.

Abstract: A method of preparing a magnetic particle having a polymer matrix (P) and at least one magnetic core (M), preferably at least two magnetic cores (M), wherein the polymer matrix (P) comprises at least one hypercrosslinked polymer, wherein the method comprises (i) providing at least one magnetic core (M), preferably at least two magnetic cores (M), (ii) providing polymer precursor molecules, (iii) polymerizing the polymer precursor molecules according to (ii) in the presence of the at least one magnetic core (M), thereby forming a particle comprising the at least one magnetic core (M) is disclosed. Further, particles obtained or obtainable by this method as well as to the use of these particles are disclosed. In a further aspect, a method for determining at least one analyte in a fluid sample having the step of contacting of the magnetic particle with a fluid sample having or suspected of having the at least one analyte is disclosed.

Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.

Abstract: The automatic analyzer includes: a liquid dispensing mechanism that performs suction of a liquid; a pressure sensor that measures a change of an internal pressure of a probe provided at the liquid dispensing mechanism; a determination section that determines whether the suction of the liquid by the probe is normal suction or air suction abnormality; an analysis section; a storage section that stores a cumulative number of times of air suction abnormality per liquid and an allowable cumulative number for the cumulative number of times of air suction abnormality; and a controller that exercises operation control over the liquid dispensing mechanism, the determination section, and the analysis section. The controller exercises control such that the cumulative number of times of air suction abnormality is updated and the updated cumulative number is stored in the storage section even if the air suction abnormality occurs non-consecutively.

Abstract: The present disclosure relates to the field of laboratory diagnostics. Specifically, means and methods are disclosed for determining a patient's risk of suffering from acute kidney injury after a surgical procedure based on the detection of GDF-15, troponin T and/or a natriuretic peptide.

Abstract: Embodiments of the present disclosure relate to method and system for diagnostic analyzing. Some embodiments of the present disclosure provide a diagnostic analyzing system. The diagnostic analyzing system comprises one or more analyzer instruments and a monitoring system, e.g. a quality control monitoring system. The one or more analyzer instruments designed for providing an analytical testing result, which is to be validated by the monitoring system using a validation algorithm. Moreover, the monitoring system may re-train the validation algorithm when a difference level between a live data set and a first training data set is greater than a threshold. Through the solution, it is possible to improve the accuracy of the validation algorithm.

Abstract: The present disclosure refers to a sensor assembly for an IVD analyzer, the sensor comprising two opposite substrates with at least one fluidic conduit for receiving a sample. The electrodes of different types of electrochemical sensors are arranged on the two opposite substrates facing the at least one fluidic conduit for coming in contact with the sample and determining sample parameters, wherein the counter electrodes and the reference electrodes are formed on one substrate and the working electrodes are formed on the opposite substrate. This achieves optimal sensor-working conditions in terms of a homogeneous and symmetrical electric field density and enables a sensor assembly with simpler geometry and smaller size.