Patents Assigned to Rohm Pharma GmbH
  • Remedy for treatment of sleep apnea
    Patent number: 5093131
    Abstract: Sleep apnea is treated by administering a therapeutically effective amount of 2-isopropyl-2,8-bis(3,4-dimethoxyphenyl)-6-methyl-6-azaoctane nitrile to a subject.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: March 3, 1992
    Assignee: Rohm Pharma GmbH
    Inventors: Karl-Dieter Volger, Werner Mohrke
  • Pharmaceutical preparations having an antihypertensive and cardioprotective effect
    Patent number: 5047235
    Abstract: A pharmaceutical preparation, which has an anti-hypertensive and cardio-protective effect, which coprises a pharmaceutically effective amount of a combination of .alpha.-isopropyl-.alpha.-[(N-methyl-N-homoveratryl)-.gamma.-aminopropyl]- 3,4-dimethoxyphenyl-acetonitrile in the form of pharmacologically acceptable acid addition salt, 2,4,7-triamino-6-phenyl-pteridine and 6-chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide as acitve ingredients, in combination with a carrier and auxiliary materials in single dosage form.
    Type: Grant
    Filed: September 30, 1988
    Date of Patent: September 10, 1991
    Assignee: Rohm-Pharma GmbH
    Inventors: Klaus Lossnitzer, Karl-Friedrich Ober, Gerhard Giebenhain, Gerhard Zeiss, Karl-Dieter Volger
  • Dermally acting pharmaceutical preparation with liposomes as vehicle means
    Patent number: 4954345
    Abstract: The present invention is directed to a pharmaceutical preparation for external or transdermal application which comprises a dispersion of liposomes, wherein said liposomes incorporate or enclose an active ingredient.
    Type: Grant
    Filed: August 15, 1988
    Date of Patent: September 4, 1990
    Assignee: Rohm Pharma GmbH
    Inventor: Joseph Muller
  • Pharmaceutical material for the treatment of psoriasis
    Patent number: 4826677
    Abstract: The invention relates to pharmaceutical materials for local and non-irritating therapy for psoriasis, containing antipsoriatic ingredients. The pharmaceutical material is a liquid preparation of film-forming polymers and antipsoriatic ingredients, with which the psoriasis affected skin area can be covered and treated in situ with a medicated film or foil formed at the treatment site. Dithranol and/or glucocorticoid in combination with keratolytically acting urea are preferred for use as antipsoriatic ingredients.
    Type: Grant
    Filed: April 2, 1987
    Date of Patent: May 2, 1989
    Assignee: Rohm Pharma GmbH
    Inventors: Josef Mueller, Hans-Ulrich Petereit
  • Quick-acting diuretic compositions
    Patent number: 4335119
    Abstract: A diuretically active pharmacological composition which comprises 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid (furosemide) together with at least one compound of formula (I) ##STR1## wherein R is a hydrophilic radical, capable of increasing the water solubility of the resulting compound together with a suitable pharmacological carrier.
    Type: Grant
    Filed: March 30, 1979
    Date of Patent: June 15, 1982
    Assignee: Rohm, Pharma GmbH
    Inventor: Andreas Johnsen
  • Treatment of Parkinson's disease
    Patent number: 4331687
    Abstract: What is disclosed is a method for the treatment of Parkinsonism or of psychic disturbances in a patient suffering therefrom, which method comprises orally or parenterally administering to said patient an effective amount of an active agent selected from the group consisting of (+)-trans-2-phenylcyclopropyl amine and physiologically acceptable acid addition salts thereof, said agent being essentially free of the corresponding (-)-enantiomer and its salts.
    Type: Grant
    Filed: March 3, 1981
    Date of Patent: May 25, 1982
    Assignee: Rohm Pharma GmbH
    Inventors: Karl-Dieter Voelger, Ilse Treudler
  • Substituted pteridine compounds and pharmaceutical compositions containing the same
    Patent number: 4252809
    Abstract: Pharmaceutical compositions having a diuretic effect and containing as the active ingredient a compound of the formula ##STR1## wherein R is hydrogen, a pharmaceutically acceptable cation, methyl, or a hydrophilic group R', are disclosed, as are novel compounds wherein R is R'.This application is a continuation-in-part of application Ser. No. 860,824 filed Dec. 15, 1977, now abandoned.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: February 24, 1981
    Assignee: Rohm Pharma GmbH
    Inventors: Heinrich Knauf, Ernst Mutschler, Karl-Dieter Voelger
  • Cardio-protective pharmaceutical composition
    Patent number: 4157394
    Abstract: A cardio-protective pharmaceutical composition is disclosed, which composition comprises an inert carrier and a pharmaceutically-effective amount of a combination of 2,4,7-triamino-6-phenyl-pteridine (triamterene) and a calcium antagonist, such as .alpha.-isopropyl-.alpha.-[(N-methyl-N-homoveratryl)-.gamma.-aminopropyl]- 3,4-dimethoxyphenyl-acetonitrile-hydrochloride (verapamil).
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: June 5, 1979
    Assignee: Rohm Pharma GmbH
    Inventors: Albrecht Fleckenstein, Johanna Janke, Klaus Lossnitzer, Karl-Dieter Voelger