Abstract: The present invention relates to hydrophobic modified peptides for the specific delivery of compounds to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the compound(s) to be specifically delivered to the liver. The present invention furthermore relates to the use of the inventive hydrophobic modified peptides as well as to a method for the prevention and/or treatment of liver diseases or disorders.
Type:
Application
Filed:
February 10, 2012
Publication date:
February 6, 2014
Applicant:
RUPRECHT-KARIS-UNVERSITAT HEIDELBERG
Inventors:
Walter Mier, Stephan Urban, Stefan Mehrle, Uwe Haberkorn