Patents Assigned to Sagres Discovery, Inc.
  • Patent number: 8252267
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of diseases, including cancer. The invention provides novel splice products of human DKKL-1 gene. The present invention provides methods of using polynucleotides having the novel splice products of the human DKKL-1 sequences, their corresponding gene products and modulators of the DKKL-1 splice products for the detection, diagnosis, prevention and/or treatment of associated cancers.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: August 28, 2012
    Assignee: Sagres Discovery, Inc.
    Inventors: Albert Lai, Robert Booher
  • Patent number: 7919246
    Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the SEM A4D gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the SEMA4D gene.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: April 5, 2011
    Assignees: Novartis Vaccines and Diagnostics, Inc., Sagres Discovery, Inc.
    Inventors: Albert Lai, Abdallah Fanidi, Robert Booher, Christin Tse, Xie Xu, Guoying Yu, Edward Moler, Michael Rowe
  • Patent number: 7892730
    Abstract: The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially lymphoma carcinomas. In addition, the present invention describes the use of novel compositions for use in screening methods.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: February 22, 2011
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Eric K. Engelhard
  • Patent number: 7820447
    Abstract: The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially lymphoma carcinomas. In addition, the present invention describes the use of novel compositions for use in screening methods.
    Type: Grant
    Filed: December 26, 2001
    Date of Patent: October 26, 2010
    Assignee: Sagres Discovery Inc.
    Inventors: David W. Morris, Eric K. Engelhard
  • Patent number: 7816076
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: October 19, 2010
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Marc S. Malandro
  • Publication number: 20100216713
    Abstract: The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods. The invention provides compositions and methods associated with altered expression of PRLR in cancer.
    Type: Application
    Filed: January 12, 2010
    Publication date: August 26, 2010
    Applicant: Sagres Discovery Inc.
    Inventors: David W. Morris, Eric K. Engelhard
  • Patent number: 7767387
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: August 3, 2010
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Marc S. Malandro
  • Patent number: 7700274
    Abstract: The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: April 20, 2010
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Eric K. Engelhard
  • Patent number: 7645441
    Abstract: The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods. The invention provides compositions and methods associated with altered expression of PRLR in cancer.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: January 12, 2010
    Assignee: Sagres Discovery Inc.
    Inventors: David W. Morris, Eric K. Engelhard
  • Publication number: 20090317391
    Abstract: This invention is in the field of cancer-related genes. Specifically it relates to methods for detecting cancer or the likelihood of developing cancer based on the presence or absence of the tm-PTP? gene or proteins encoded by this gene. The invention also provides methods and molecules for upregulating or downregulating the tm-PTP? gene.
    Type: Application
    Filed: April 7, 2006
    Publication date: December 24, 2009
    Applicants: NOVARTIS VACCINES AND DIAGNOSTICS INC., SAGRES DISCOVERY INC.
    Inventors: Abdullah Fanidi, Robert Booher, Albert Lai, Christin Tse
  • Publication number: 20090215711
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: April 30, 2004
    Publication date: August 27, 2009
    Applicant: Sagres Discovery, Inc.
    Inventors: David W. Morris, Marc S. Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Patent number: 7332281
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: February 19, 2008
    Assignee: Sagres Discovery, Inc.
    Inventors: David W. Morris, Marc S. Malandro, Albert Lai, Christin Tse, Ali Fattaey
  • Publication number: 20040197778
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is dys-regulated in cancer tissues. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
    Type: Application
    Filed: December 26, 2002
    Publication date: October 7, 2004
    Applicant: Sagres Discovery, inc.
    Inventors: David W. Morris, Marc S. Malandro