Abstract: A method and system for cooling and effecting a change of state of a liquid mixture, wherein the liquid mixture is atomized to form an atomized liquid mixture, which is cooled to change its physical state, the cooling being performed using substantially gaseous coolant.

Abstract: A process is disclosed for pressing a material selected from materials of vegetable and animal origin. The process includes the steps of mechanically compressing the material of vegetable or animal origin while simultaneously vibrating the material at an ultrasonic frequency. The ultrasonic frequency going through the material modifies the material's internal state so as to considerably reduce resistance offered by the material to mechanical compression.

Abstract: Controlled release solid forms, apparatus and method for preparing solid forms for controlled release of an active ingredient.

Abstract: An improved process for preparing controlled release pharmaceutical forms comprises exposing a mixture comprising one or more excipients and one or more active ingredients compatible with each other and with said excipients to mechanical or electromechanical actions for a well established time and within a wide range of frequencies to give tablets, matrices or mono or multilayered films. Said forms can be optionally crushed to give a granulate or powder. Depending on the employed excipient, a delayed or rapid but always controllable release of the active ingredient can be attained.