Patents Assigned to Sami Labs Limited
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Patent number: 11865203Abstract: Disclosed are the skin care applications of a composition containing the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856. More specifically, the invention discloses the ability of the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to confer protection to the skin fibroblasts against UV induced cell damage and apoptosis, oxidative stress and inflammation.Type: GrantFiled: May 19, 2021Date of Patent: January 9, 2024Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed, Lakshmi Mundkur
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Patent number: 11458117Abstract: Disclosed are the uses of compositions containing not less than 10% w/w of Oroxylin A, not less than 10% w/w of Baicalein and not less than 2% w/w of Chrysin in inhibiting the activity and expression of ? secretase. The invention also discloses the reduction of amyloid content in PS-70 cells using the abovementioned composition. Further, the invention mentions the use of the composition for the therapeutic management of ? secretase mediated disorders.Type: GrantFiled: June 14, 2018Date of Patent: October 4, 2022Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam
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Patent number: 11332702Abstract: A probiotic-alcoholic beverage composition comprising Bacillus coagulans is disclosed herein wherein the said spore or vegetative cell of Bacillus coagulans exhibited high recovery, tolerability, compatibility and viability of spores and vegetative cells after brewing. Methods for brewing an alcoholic beverage composition comprising Bacillus coagulans wherein said spore or bacterium is added during pre-fermentation, during fermentation and post fermentation stages are also disclosed.Type: GrantFiled: September 20, 2018Date of Patent: May 17, 2022Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed, Kirankumar Beede
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Patent number: 11298395Abstract: The present invention relates to a process for the isolation of bioactive components from spent turmeric (Curcuma longa) and compositions comprising said bioactive components. Further, the present invention also elucidates the potent anti-inflammatory activity of said bioactive compositions and therapeutic applications thereof in rheumatoid arthritis.Type: GrantFiled: July 17, 2018Date of Patent: April 12, 2022Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat, Natarajan Sankaran
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Patent number: 11298381Abstract: The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.Type: GrantFiled: April 29, 2019Date of Patent: April 12, 2022Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Furqan Ali, Sivakumar Arumugam, Shaheen Majeed, Lakshmi Mundkur, Anurag Pande
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Patent number: 11213553Abstract: Disclosed is the hypolipidemic potential of Bacillus coagulans. More specifically the invention discloses the cholesterol lowering potential of Bacillus coagulans MTCC 5856 and therapeutic/biological indications thereof.Type: GrantFiled: February 22, 2018Date of Patent: January 4, 2022Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed
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Patent number: 11197898Abstract: The present invention discloses a novel fructophilic lactic acid producing bacteria Bacillus coagulans strain FF-7 (MTCC 25235) and the process of isolation and characterization of the bacteria. The invention also discloses the biological applications/therapeutic use of fructophilic lactic acid producing bacteria in increased utilization of fructose from food stuff and in the managing disorders related to high fructose intake.Type: GrantFiled: May 13, 2019Date of Patent: December 14, 2021Assignee: Sami Labs LimitedInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Furqan Ali, Sivakumar Arumugam, Shaheen Majeed, Kirankumar Beede
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Patent number: 11123382Abstract: Disclosed are hair care compositions containing partially purified extracellular metabolite preparation from strains of Bacillus coagulans. Specifically, the uses of compositions containing extracellular metabolite preparation from a strain of Bacillus coagulans for increasing hair growth, inhibition of 5?-reductase and proliferation of follicle dermal papilla cells and in the management of androgenic alopecia, are disclosed.Type: GrantFiled: June 1, 2018Date of Patent: September 21, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed, Lakshmi Mundkur
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Patent number: 11122814Abstract: The present invention discloses beverage compositions comprising probiotic Bacillus coagulans and water soluble prebiotic fibers that have been subjected to treatments under extreme stress, temperature and pressure conditions like brewing or aeration wherein the spore viability is maintained post said treatments.Type: GrantFiled: February 26, 2020Date of Patent: September 21, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Shaheen Majeed
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Publication number: 20210267880Abstract: Disclosed are the skin care applications of a composition containing the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856. More specifically, the invention discloses the ability of the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to confer protection to the skin fibroblasts against UV induced cell damage and apoptosis, oxidative stress and inflammation.Type: ApplicationFiled: May 19, 2021Publication date: September 2, 2021Applicant: SAMI LABS LIMITEDInventors: Muhammed MAJEED, Kalyanam NAGABHUSHANAM, Sivakumar ARUMUGAM, Furqan ALI, Shaheen MAJEED, Lakshmi MUNDKUR
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Patent number: 11052125Abstract: The present invention discloses a composition comprising extracts of Cyperus rotundus, standardized to contain 3-5% w/w total stilbenes, extracts of Garcinia sp., standardized to contain 20% w/w garcinol and extracts of Coleus forskohlii standardized to contain not less than 10% w/w forskolin for the therapeutic management of diet induced obesity and weight gain and related conditions like liver dysfunction, NASH, NAFLD, liver cirrhosis, hypercholesterolemia, hyperlipidemia, kidney dysfunction by bringing about a reduction in body weight, increasing lean body mass and by normalizing the levels of liver enzymes, kidney markers and circulating lipids.Type: GrantFiled: April 29, 2019Date of Patent: July 6, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur, Sarang Bani, Anjali Pandey
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Patent number: 11045517Abstract: The present invention discloses a composition comprising Nigella sativa extract standardized to contain not less than 0.1% w/w thymoquinone and not less than 0.01% w/w thymohydroquinone, Coleus forskolii extract standardized to contain not less than 90% w/w forskolin and Piper nigrum extract standardized to contain not less than 95% w/w piperine extract for use in enhancing melanogenesis in mammalian cells. The invention also discloses the use of above mentioned composition in the therapeutic management of hypomelanotic skin conditions and in reducing the progression of depigmentation of skin in vitiligo in mammalian skin.Type: GrantFiled: February 10, 2020Date of Patent: June 29, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Prasad M Peethambaran, Lakshmi Mundkur
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Patent number: 10966919Abstract: Disclosed is the use of partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to prevent skin aging. More specifically the invention discloses the anti-collagenase, anti-elastase, anti-glycation activity and enhancement of TGF-?, epidermal growth factor and hyaluronic acid expression in human dermal fibroblasts, of extracellular metabolites isolated from Bacillus coagulans MTCC 5856.Type: GrantFiled: June 4, 2018Date of Patent: April 6, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali, Lakshmi Mundkur, Shaheen Majeed
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Patent number: 10945969Abstract: Disclosed are compositions enriched with thymohydroquinone, further comprising of thymoquinone, hederagenin and/or ?-hederin formulated by blending the active molecules isolated from the seeds of Nigella sativa. Also disclosed are novel processes for the isolation of bioactive components thymohydroquinone, thymoquinone from the seeds of Nigella sativa. A process for the isolation ?-hederin and hederagenin from the spent material of Nigella sativa is also disclosed herein.Type: GrantFiled: December 26, 2018Date of Patent: March 16, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Beena Bhat
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Patent number: 10898536Abstract: The invention discloses the anti-acne potential of ? and ? pyranocycloartobiloxanthone A and Artonine E, isolated from the stem bark of Artocarpus hirsutus by inhibiting the growth of Propionibacterium acnes.Type: GrantFiled: December 22, 2016Date of Patent: January 26, 2021Assignee: Sami Labs LimitedInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Mahadeva Nayak, Nagarajan Ananthanarayanan
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Patent number: 10894029Abstract: Disclosed are compositions containing not less than 10% w/w of oroxylin A, not less than 10% w/w of baicalein and not less than 2% w/w of chrysin for use in the therapeutic management of memory impairment and cognitive dysfunction. More specifically, the invention discloses the use of abovementioned compositions for the management of cognitive impairment induced by chemotherapy and hyperglycemia.Type: GrantFiled: June 15, 2018Date of Patent: January 19, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam
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Patent number: 10881623Abstract: Disclosed is a method for therapeutic management of hyperglycemia in mammals using compositions containing thymohydroquinone. More specifically, the invention discloses compositions containing thymohydroquinone for inhibiting the activity of the enzyme ?-glucosidase and increasing the cellular uptake of glucose by mammalian cells. The anti-oxidant, anti-inflammatory and anti-glycation effects of thymohydroquinone are also disclosed herein.Type: GrantFiled: December 26, 2018Date of Patent: January 5, 2021Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
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Patent number: 10864154Abstract: The present invention discloses a synergistic composition comprising 3-O-ethyl-ascorbic acid and tetrahydrocurcuminoids for use as a skin lightening agent. The invention also discloses a method of inhibiting melanin biosynthesis and tyrosinase activity in mammalian skin cells using a composition comprising 3-O-ethyl-ascorbic acid and tetrahydrocurcuminoids.Type: GrantFiled: April 2, 2019Date of Patent: December 15, 2020Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Lakshmi Mundkur
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Patent number: 10864243Abstract: The present invention discloses a composition comprising Allium sativum extract standardized to contain not less that 0.3% w/w S-allylcysteine, Beta vulgaris extract standardized to contain not less than 2% w/w nitrates, Nigella sativa extract standardized to contain 0.1%-5% w/w thymoquinone, about 0.01%-10% w/w thymohydroquinone, about 20%-95% w/w fatty acids, about 0.001%-3% w/w ?-hederin or hederagenin, and Terminalia arjuna extract standardized to contain 3% w/w arjunoglucosides for use a prostaglandin transporter inhibitor. The invention also discloses the use of the aforementioned composition in the therapeutic management of hypertension and cardiovascular complications.Type: GrantFiled: June 6, 2019Date of Patent: December 15, 2020Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sarang Bani, Anjali Pandey
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Patent number: 10864242Abstract: The present invention discloses a composition for the therapeutic management of male sexual dysfunction and related disorders. Specifically, the invention discloses a composition comprising 60-65% w/w Withania somnifera extract, 12-18% w/w Mucana pruriens extract, 5-10% w/w Coleus forskolii extract, 12-18% w/w Kaempferia parviflora extract, 0.1-2% w/w Piper nigrum extract, for use as an aphrodisiac.Type: GrantFiled: April 17, 2019Date of Patent: December 15, 2020Assignee: SAMI LABS LIMITEDInventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sarang Bani, Anjali Pandey