Abstract: Disclosed are an oral solid dosage form composition comprising an active ingredient and a solubilizing carrier wherein a foaming ingredient is used to improve disintegration, dispersion or dissolution, and a preparation method therefor.
Type:
Grant
Filed:
October 30, 2018
Date of Patent:
May 14, 2024
Assignee:
SAMYANG HOLDINGS CORPORATION
Inventors:
Sang Yeob Park, Hye Jung Lim, Jae Young Lee, Min Hyo Seo, Sa Won Lee
Abstract: Disclosed is a mucoadhesive pharmaceutical composition comprising a poly-ionic complex of chitosan and a polyacrylic acid polymer. As an oral formulation, the composition has the extended retention time in the gastrointestinal tract by its mucoadhesive and swelling properties, which is useful as sustained release formulations, retentive formulations of active ingredients with limited absorption regions, and active ingredients with pH dependent solubility.
Abstract: The present invention relates to a composition for hydrogel formation, a hydrogel formed by photo-crosslinking same, and a method for preparing the hydrogel and, more specifically, to a composition which comprises a photo-initiator and a polyglutamic acid polymer having a photo-crosslinkable functional group introduced thereto and is capable of forming a hydrogel in real time through photo-crosslinking, to a hydrogel which is formed by photo-crosslinking the composition and can be utilized as a tissue adhesive, a surgical sealant, anti-adhesive agent, or the like due to excellent biocompatibility, superior adhesive strength in wet environments, flexibility, and ease of use, and to a method for preparing the hydrogel.
Type:
Application
Filed:
August 5, 2021
Publication date:
September 21, 2023
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Ji Hyun CHANG, Hyung Hwan KIM, Hye Sung YOON
Abstract: The present invention relates to a medical thread which has on one end thereof a stopper that has a polygonal cross-section, and which exhibits excellent end adhesive force and penetration resistance, and to a manufacturing method for same.
Type:
Application
Filed:
March 24, 2021
Publication date:
June 22, 2023
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Ho Sung LEE, Dae Hui RYU, Hye Sung YOON
Abstract: A sealant syringe assembly includes a first syringe including a plurality of chambers and discharging a first solution which is a mixture of a buffer solution and compound powder; a reaction solution syringe including at least one chamber and discharging a reaction solution capable of reacting with the first solution; and a connector for connecting the first syringe and the reaction solution syringe to mix and discharge the first solution and the reaction solution. The first syringe includes three packing members provided inside the first syringe; a passage provided in the inner circumferential surface of the first syringe; and a plunger for providing a pressure to one of the packing members.
Type:
Grant
Filed:
August 7, 2018
Date of Patent:
May 2, 2023
Assignee:
SAMYANG HOLDINGS CORPORATION
Inventors:
Young Joo Koh, Hyung Hwan Kim, Jung Ha Park
Abstract: The present invention relates to a kit for preparing a nanoparticle composition for drug delivery and, more specifically, to a kit for preparing a nanoparticle composition for drug delivery, which is designed to easily form a nanoparticle in which a drug is encapsulated by simply mixing an amphiphilic block copolymer, a cationic compound, a polylactic acid salt, and the drug that are the components of the kit.
Type:
Application
Filed:
December 16, 2020
Publication date:
February 9, 2023
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
So Jin LEE, Sang Hoon KIM, Joon Young PARK, Hye Yeong NAM, Ji Yeon SON
Abstract: The present invention relates to a kit for preparing a nanoparticle composition for drug delivery and, more specifically, to a kit for preparing a nanoparticle composition for drug wherein the kit is designed such that the kit does not comprise a polylactic acid salt and nanoparticles containing a drug encapsulated therein can be easily formed just by simply mixing an amphiphilic block copolymer, a cationic compound, and a drug as components of the kit.
Type:
Application
Filed:
November 19, 2020
Publication date:
January 19, 2023
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
So Jin LEE, Sang Hoon KIM, Joon Young PARK, Hye Yeong NAM, Ji Yeon SON
Abstract: Disclosed are a composition for inducing immunity against an active ingredient and a method for preparing same, the composition comprising: a nucleic acid, a polypeptide, or a combination thereof as the active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the active ingredient is encapsulated in a nanoparticle structure formed by the amphiphilic block copolymer and the polylactate.
Type:
Application
Filed:
November 5, 2020
Publication date:
December 29, 2022
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
So Jin LEE, Joon Young PARK, Hye Yeong NAM, He Len CHO, Goo Young KIM
Abstract: The present invention relates to an emulsion composition for chemoembolization comprising a nanoparticle comprising a drug and a biocompatible polymer, a water-soluble contrast agent and a water-insoluble contrast agent, and a water-insoluble drug as well as an aqueous drug can be administered in a form of stable emulsion, and drugs are slowly released, thereby enhancing the effect of chemoembolization.
Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.
Type:
Grant
Filed:
April 24, 2020
Date of Patent:
October 11, 2022
Assignee:
SAMYANG HOLDINGS CORPORATION
Inventors:
Bong Oh Kim, Bum Chan Min, Ji Yeong Kim, Hye Rim Kim, Min Hyo Seo, Sa Won Lee, Yil Woong Yi, Joong Woong Cho, In Ja Choi
Abstract: The present invention relates to: a virus-containing pharmaceutical composition, which comprises, as an active ingredient, a virus for treating or preventing disease; and a preparation method therefor.
Type:
Application
Filed:
August 7, 2019
Publication date:
August 18, 2022
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Joung Woo CHOI, Sang Hoon KIM, Hye Yeong NAM, Helen CHO, Min Hyuk YUN, Goo Young KIM, So Jin LEE
Abstract: In order to provide a means for fixing an end of a medical suture to skin tissue in a short time and thereby reduce an operation time, the present invention provides: a medical suture comprising a main body, which extends in the length direction, and a stopper, which is at one end of the main body and has a larger cross section than the main body; and a method for producing same.
Type:
Application
Filed:
March 27, 2020
Publication date:
August 18, 2022
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Ho Sung LEE, Dae Hui RYU, Hye Sung YOON
Abstract: The present invention relates to an apparatus for manufacturing a fibrous web, a fibrilla fiber aggregate, or a nonwoven fabric by using a woven fabric, a method for manufacturing a fibrous web, a fibrilla fiber aggregate, or a nonwoven fabric by using the apparatus, and a fibrous web, a fibrilla fiber aggregate, or a nonwoven fabric manufactured by the method, especially, a fibrous web, a fibrilla fiber aggregate, or a nonwoven fabric for use in a hemostatic agent or an anti-adhesive agent.
Abstract: Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate.
Type:
Application
Filed:
January 10, 2022
Publication date:
April 28, 2022
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Hye Yeong NAM, Bong-Oh KIM, Min-Hyo SEO, Ji-Yeon SON, Ji-Hye CHOI, Sang Hoon KIM
Abstract: The present invention relates to a powder type hemostatic composition and method for preparing the same, and more specifically, to powder aggregate having porosity obtained by combining powder of biocompatible hemostatic material with a binder and a method for preparing the same, and a powder type hemostatic composition which comprises the powder aggregate and shows improved hemostatic performance as compared with simple powder hemostatic agents, and can be used to a large surface area for hemostasis, or to narrow, thin or other sites to which approach for hemostasis is difficult.
Type:
Application
Filed:
October 30, 2020
Publication date:
December 2, 2021
Applicant:
SAMYANG HOLDINGS CORPORATION
Inventors:
Hyun Kyoon KIM, Beom Kang HUH, Hye Sung YOON, Suk Yen KO
Abstract: The present invention relates to an amphiphilic block copolymer composition which provides enhanced stability to a micelle formed by an amphiphilic block copolymer in an aqueous phase.