Abstract: The technology relates to monoclonal antibodies useful in the identification of cancer cells. In one embodiment, mAbs with specificity for tumor antigens are provided. In one embodiment, methods for treating cancer using mAbs are provided. In another embodiment, methods for detecting cancerous cells are provided. In another embodiment, kits for detecting cancerous cells are provided.
Type:
Application
Filed:
May 16, 2012
Publication date:
November 22, 2012
Applicant:
Sanofi Pasteur, Ltd.
Inventors:
Neil Berinstein, Devender Satsangi Singh Sandhu, Corey Lovitt, Artur Pedyczak, Scott Gallichan, Laszlo Radvanyi
Abstract: The technology relates to monoclonal antibodies useful in the identification of cancer cells. In one embodiment, mAbs with specificity for tumor antigens are provided. In one embodiment, methods for treating cancer using mAbs are provided. In another embodiment, methods for detecting cancerous cells are provided. In another embodiment, kits for detecting cancerous cells are provided.
Type:
Application
Filed:
July 14, 2010
Publication date:
February 24, 2011
Applicant:
Sanofi Pasteur, Ltd.
Inventors:
Neil Berinstein, Devender Singh-Sandhu, Corey Lovitt, Artur Pedyczak, Laszlo Radvanyi
Abstract: Provided herein are compositions and methods for eliciting an immune response against Streptococcus pneumoniae. More particularly, the compositions and methods relate to immunogenic polypeptides, including fragments of PcpA and variants thereof, and nucleic acids, vectors and transfected cells that encode or express the polypeptides. Methods of making and using the immunogenic polypeptides are also described.
Type:
Application
Filed:
August 17, 2007
Publication date:
January 6, 2011
Applicants:
THE UAB RESEARCH FOUNDATION, SANOFI PASTEUR LTD.
Inventors:
David E. Briles, Susan K. Hollingshead, Jeremy Yethon, Joe Wang
Abstract: The technology relates to monoclonal antibodies useful in the identification of cancer cells. In one embodiment, mAbs with specificity for tumor antigens are provided. In one embodiment, methods for treating cancer using mAbs are provided. In another embodiment, methods for detecting cancerous cells are provided. In another embodiment, kits for detecting cancerous cells are provided.
Type:
Application
Filed:
February 8, 2007
Publication date:
November 13, 2008
Applicant:
Sanofi Pasteur, Ltd.
Inventors:
Neil Berinstein, Devender Singh-Sandhu, Corey Lovitt, Artur Pedyczak, Laszlo Radavanyi