Patents Assigned to Sartorius AG
  • Patent number: 10344254
    Abstract: Reactor plant and process for culturing phototropic microorganisms with a reactor vessel and a photosynthetic module, which are connected with one another in a circulation circuit by a pump and can be controlled via a control unit, where in the circulation circuit or in the reactor vessel, a homogenizer is provided, where a light-intensity control of the photosynthetic module is provided, and where a bypass of the circulation circuit or of the reactor vessel with a filter device which is arranged externally of the reactor vessel for separating off extracellular products during the fermentation is provided.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: July 9, 2019
    Assignee: Sartorius AG
    Inventors: Wolfgang Kahlert, Bernd-Ulrich Wilhelm, Wolf-Dietrich Linke
  • Patent number: 8846383
    Abstract: Disclosed are a method and a device for the biotechnological production of valuable products, in which a medium is fed to a bioreactor and is subjected to a fermentation process, the valuable product is gathered as a filtered permeate and/or concentrated retentate via a cross-flow filtration system that is mounted downstream thereof, and residues are once again fed to the bioreactor until being gathered as a retentate. Other materials can be fed to the bioreactor in a controlled manner in addition to the medium while the concentrated retentate and permeate can be gathered in a controlled manner. The fermentation process and the filtration process are regulated in a synchronized manner in an integrated system via a digital control unit.
    Type: Grant
    Filed: June 21, 2003
    Date of Patent: September 30, 2014
    Assignee: Sartorius AG
    Inventors: Reiner Luttmann, Wilfried Kappel, Toralf Gliem, Mohammad Saeed Ajam, Lars Boettcher, Bernd-Ulrich Wilhelm, Wolfgang Rietschel
  • Patent number: 8343350
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: January 1, 2013
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Hörl
  • Patent number: 8343351
    Abstract: The invention comprises a membrane and device and method for removing proteases from fluids, particularly from biological fluids and pharmaceutical solutions, which uses a microporous membrane body, whereby inhibitors that selectively bind proteases are coupled to the membrane body by chemically activated groups.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: January 1, 2013
    Assignee: Sartorius AG
    Inventors: Wolfgang Demmer, Dietmar Nussbaumer, Hans-Heinrich Hörl
  • Publication number: 20110278077
    Abstract: A top-pan balance having a pan, a weighing system, and an overload safety mechanism. The load cell (4) of the weighing system is connected to fixed points (1) on a housing of the weighing system by an upper connecting rod (2) and a lower connecting rod (3) as a parallel guide so as to be movable in the vertical direction. The pan is attached to a pan support (8/9) for securing against overload, the support being connected to the load cell through an auxiliary parallel guide (15/16) and through a biased spring element (17/18), whereby the pan is quasi rigidly coupled to the load cell in the permissible weighing range, but is only resiliently coupled to the load cell when the permissible weighing range is exceeded. At least one limit stop is fixed to the housing and limits the elastic deflection of the pan and the pan support in case of overload.
    Type: Application
    Filed: May 16, 2011
    Publication date: November 17, 2011
    Applicant: SARTORIUS AG
    Inventors: Detlev ERBEN, Helga COVIC, Jochen DOERNER
  • Publication number: 20110209926
    Abstract: Force plate (1) having a plate-shaped carrier (2) which, when arranged vertically, has an upper carrier section (3) at the top in the vertical direction and a lower carrier section (4) at the bottom in the vertical direction. A first end carrier section (5) is connected, on the one hand, to the upper carrier section (3) via a vertical rod (7) and, on the other hand, to the lower carrier section (4) via a horizontally oriented spring element (6). That end of the lower carrier section (4) which faces away from the first end carrier section (5) is connected to the upper carrier section (3) via a horizontal rod (8). A second end carrier section (15) connects the horizontal rod (8) to the lower carrier section (4) via a vertically arranged spring element (16).
    Type: Application
    Filed: May 10, 2011
    Publication date: September 1, 2011
    Applicant: SARTORIUS AG
    Inventors: Otto KUHLMANN, Tanja MUECK, Volker RELLING, Gerald PETZOLD
  • Publication number: 20110148597
    Abstract: A dosing system and a method for dosing a medium, having a dosing control unit (4), at least one exchangeable container (2) containing a medium to be dosed, and a dosing valve (3, 3?) that can be connected to the container (2), wherein at least one part of the dosing valve (3, 3?) that comes into contact with the medium is designed as an exchangeable system component (7, 10) and has a machine-readable code for identification purposes, wherein at least one container (2), as an exchangeable system component (2), has a machine-readable code for identification purposes, wherein the exchangeable parts (2, 7, 10, 19) that come into contact with the medium are designed as disposable parts, and wherein the dosing control unit (4) is connected with a communication unit (5) to read the codes, and wherein the communication unit (5) has a unique read connection (22) to each exchangeable system component (2, 7, 10, 19) or its code.
    Type: Application
    Filed: November 5, 2009
    Publication date: June 23, 2011
    Applicants: SARTORIUS STEDIM BIOTECH GMBH, SARTORIUS AG
    Inventors: Oscar-Werner Reif, Reinhard Baurnfalk, Dieter Schmidt, Christian Oldendorf, Swen Weitemeier
  • Patent number: 7964806
    Abstract: An electronic scale having a measuring sensor (1 . . . 16), a digital signal processing unit (18), a digital display (19), a bubble level (20), which includes a container (21) that is partially filled with a liquid (22) while forming a gas bubble (23), and circuit component or program routine in the digital signal processing unit (18) for detecting a displacement of the gas bubble (23). An additional circuit component or program routine detects the diameter of the gas bubble (23). The diameter of the gas bubble changes due to vertical vibrations of the scale. The signal from the measuring sensor (1 . . . 16) falsified by vibrations can thus be corrected by the digital signal processing unit (18) by calculation, making use of the diameter signal.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: June 21, 2011
    Assignee: Sartorius AG
    Inventors: Gerd Freydank, Winfried Graf, Christian Oldendorf
  • Publication number: 20110140731
    Abstract: An electronic device, and associated method, provided with a circuit board (10) with a set of input contacts (IN/COM), a set of output contacts (OUT/COM) and an electrical circuit (18) connected between the input contacts (IN/COM) and the output contacts (OUT/COM), and a controller. The controller carries out a real-time test of the circuit board using a test signal introduced into the electrical circuit, the electrical circuit (18) being designed as a passive network having a characteristic transfer function and provided with at least one inductive element, which is formed by a conductor wire (201) wound into a coil around a break (202) in the circuit board (10), which in the assembled condition, is penetrated by a ferromagnetic bar or fixing pin (203), such that the inductance of the inductive element in the assembled state differs from the inductance thereof in the disassembled state.
    Type: Application
    Filed: December 2, 2010
    Publication date: June 16, 2011
    Applicant: SARTORIUS AG
    Inventors: Swen Weitemeier, Christian Oldendorf
  • Publication number: 20110133752
    Abstract: An electronic device, and associated method, provided with a circuit board (10), with a set of input contacts (IN/COM), a set of output contacts (OUT/COM) and an electrical circuit (18) connected between the input contacts (IN/COM) and the output contacts (OUT/COM) and a controller. The controller carries out a real-time test of the circuit board using a test signal introduced into the electrical circuit, the electrical circuit (18) being designed as a passive network having a characteristic transfer function and provided with at least one capacitive element, wherein the capacitive element is a conductor surface (221) forming a capacitor in the assembled state with a corresponding, device-side conductor surface (222?), which is connected to the electrical circuit (18) via a contact element in the assembled state, whereby the capacitive value of the capacitive element in the assembled state differs from the capacitive value of the capacitive element in the disassembled state.
    Type: Application
    Filed: December 2, 2010
    Publication date: June 9, 2011
    Applicant: SARTORIUS AG
    Inventors: Swen Weitemeier, Christian Oldendorf
  • Publication number: 20110132669
    Abstract: A balance having at least one adjusting device (2, . . . ) having a drive, wherein the drive of the adjusting device is configured as a fluidic drive (4, . . . ), to which pressure can be applied by a pressure source disposed outside the scales via a pressure connection.
    Type: Application
    Filed: June 4, 2010
    Publication date: June 9, 2011
    Applicant: SARTORIUS AG
    Inventors: Michael Laubstein, Juergen Lauke
  • Publication number: 20110133753
    Abstract: An electronic device, and associated method, provided with a circuit board (10), with a set of input contacts (IN/COM), a set of output contacts (OUT/COM) and an electrical circuit (18) connected between the input contacts (IN/COM) and the output contacts (OUT/COM) and a controller. The controller carries out a real-time test of the circuit board using a test signal introduced into the electrical circuit, the electrical circuit (18) being designed as a passive network having a characteristic transfer function and provided with at least two separate partial circuits (18?, 18?) wherein the separate partial circuits are electrically connected in the assembled state by cooperation with at least one of: at least one device components and/or assembly components (181).
    Type: Application
    Filed: December 2, 2010
    Publication date: June 9, 2011
    Applicant: SARTORIUS AG
    Inventors: Swen Weitemeier, Christian Oldendorf
  • Patent number: 7924543
    Abstract: A current-limiting circuit (100), which limits an electrical current from a voltage source to a consumer to a predetermined maximum current. A measuring resistor (110) is coupled into a current lead (103) between a circuit input (102) and a circuit output (104). A transistor (106) of the circuit is coupled into the current lead (103) with its collector-emitter path in series with the measuring resistor (110), and its base is connected to the current lead (103) through a series resistor (108). A shunt regulator (116) of the circuit has an anode, a reference input and a cathode, wherein the cathode is connected to the base of the transistor (106), and the anode and the reference input form a voltage tap across the measuring resistor (110).
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: April 12, 2011
    Assignee: Sartorius AG
    Inventor: Dieter Klausgrete
  • Patent number: 7906737
    Abstract: An electronic scale having a measuring sensor (1 . . . 16), a digital signal processing unit (18), a digital display (19) and an inclinometer (40). The inclinometer derives a signal for the tilt of the scale from the difference of at least two signals. The digital signal processing unit (18) is provided with an additional circuit component or program routine that adds the two signals and, by way of this cumulative signal, corrects the vibration-distorted signal of the measuring sensor (1 . . . 16). A plurality of inclinometers enables the simultaneous detection of momentary gravitational acceleration. For example, in an electric bubble level, the gas bubble moves out of place when tilted and the diameter of the gas bubble changes when the gravitational acceleration changes. The scale thus provides an additional signal for correcting the influence of disturbances with minimum complexity.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: March 15, 2011
    Assignee: Sartorius AG
    Inventors: Gerd Freydank, Winfried Graf, Christian Oldendorf
  • Patent number: 7847202
    Abstract: A top-pan scale with a scale pan which is supported on at least one force transducer (7) of a force measurement system (5) and with a corner load sensor which outputs a signal if the weighing goods are positioned eccentrically on the scale pan. The corner load sensor (10) has a flat underside via which it can be placed on, or attached to, the scale pan or a bottom pan of the scale. The corner load sensor also has a flat upper side on which a scale pan (4) can be placed or attached. The corner load sensor (10) is connected to a positionally fixed electronic processor (22) via a force-feedback-free connection (21). Embodiments of the corner load sensor can therefore be used for a wide variety of scale designs and can be retrofitted easily.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: December 7, 2010
    Assignee: Sartorius AG
    Inventors: Michael Mueller, Werner Schulze
  • Patent number: 7839320
    Abstract: Measurement amplification methods and devices for detecting a monopolar input signal (UE) by integrating A/D conversion. Before being digitized, the input signal (UE) is inverted according to the so-called Chopper principle and converted into a bipolar intermediate signal (UZ). A reference voltage (Uref) used in A/D conversion undergoes polarity changes synchronized with the polarity changes of the intermediate signal (UZ). Offset and drift are eliminated by totaling an even number of individual measurements.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: November 23, 2010
    Assignee: Sartorius AG
    Inventors: Heinrich Feldotte, Alfred Klauer
  • Patent number: 7830294
    Abstract: Measurement amplification methods and devices for detecting the detuning of a measurement bridge (10) to which a bipolar, rectangular supply voltage (Us) is supplied. The methods and devices use integrating A/D conversion and are characterized in that a reference voltage (Uref) used for the A/D conversion undergoes polarity changes synchronized with the polarity changes of the supply voltage (Us). Offset and drift are eliminated by totaling an even number of individual measurements.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: November 9, 2010
    Assignee: Sartorius AG
    Inventors: Heinrich Feldotte, Alfred Klauer
  • Publication number: 20100271624
    Abstract: A weighing scale, e.g. a top-pan scale, having a scale pan (01, 02) supported on a force transducer, and a corner load sensor (03, 04, 06, 08, 09) measuring the tilting of the scale pan (01, 02) relative to the force transducer. The corner load sensor includes a light beam source (03, 04, 06) emitting a first light beam and a second light beam. The first light beam and the second light beam are directed toward a reflecting surface on an underside of an arrangement that includes the scale pan (01, 02). The first light beam and the second light beam are respectively inclined relative to the reflecting surface of the untilted scale pan (01). The corner load sensor (03, 04, 06, 08, 09) of the scale also includes a first optical sensor (08) measuring the first light beam reflected by the reflecting surface. If no corner load exists, a predetermined proportion (12) of the reflected first light beam is directed to the first optical sensor (08).
    Type: Application
    Filed: April 23, 2010
    Publication date: October 28, 2010
    Applicant: Sartorius AG
    Inventors: Jochen DOERNER, Christian Schrader, Ralf Mueller
  • Patent number: 7818891
    Abstract: An inclination sensor is provided having a level that has a liquid and a gas bubble under a covering glass in a housing. A light source is arranged above the covering glass. The inclination sensor can be used to determine a direction and degree of an inclination with high accuracy and which is suitable for automatically aligning an apparatus provided with the inclination sensor. An arrangement is provided that has at least two light receivers arranged above the covering glass such that the light that is emitted from the light source and, in the case of a centered gas bubble, is scattered on the surface of the covering glass coming in contact with the gas bubble can be detected by the at least two light receivers. Different quantities of light can be detected by the light receivers when the gas bubble is not centered, and the light source and the light receivers are arranged on a chip substrate.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: October 26, 2010
    Assignee: Sartorius AG
    Inventors: Dieter Roemhild, Gerd Freydank, Herbert Rink, Olaf Brodersen, Ralf Mueller
  • Publication number: 20100263940
    Abstract: A weighing device having a plurality of digital weighing cells (164), each including a sensor connected to a force transmission unit (163), each generating a digital measurement value corresponding to a transmitted force at a measurement time point, and including a data processing device that converts the digital measurement values to transmission units configured to be transmitted over a data communications line (20) to a central control unit (18) connected to all weighing cells for analysis of the transmission units. The central control unit (18) calculates a digital combination value based on the transmission units originating from the various weighing cells (164), the combination value representing a weight force with which the weighing device (16) is loaded at a weighing time point. The conversion of the measurement values to transmission units involves a pairing of each converted measurement value with a time value.
    Type: Application
    Filed: June 7, 2010
    Publication date: October 21, 2010
    Applicant: SARTORIUS AG
    Inventors: Alfred KLAUER, Christian Oldendorf, Thomas Schink, Erich Bettwieser