Patents Assigned to SCANDINAVIAN BIOPHARMA HOLDING AB
  • Vaccine for protection against ETEC-induced diarrhea comprising dmLT
    Patent number: 11918636
    Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: March 5, 2024
    Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB, C/O ETVAX AB
    Inventors: Ann-Mari Svennerholm, Joshua Tobias, Nils Carlin, Jan Holmgren
  • Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
    Patent number: 11820798
    Abstract: A method for increase the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: November 21, 2023
    Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias
  • Vaccine for protection against ETEC-induced diarrhea comprising dmLT
    Patent number: 11052143
    Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: July 6, 2021
    Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
    Inventors: Ann-Mari Svennerholm, Joshua Tobias, Nils Carlin, Jan Holmgren
  • Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
    Patent number: 10851140
    Abstract: A method for increase the presentation of ETEC CS6 antigen on a cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: December 1, 2020
    Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias
  • Vaccine for protection against ETEC-induced diarrhea comprising dmLT
    Patent number: 10548961
    Abstract: An oral vaccine for immunization against ETEC-induced diarrhea, comprising inactivated Escherichia coli cells expressing an ETEC colonization factor antigen and dmLT protein adjuvant, wherein the vaccine preferably comprises less than 1013 cells per unit dose.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: February 4, 2020
    Assignee: SCANDINAVIAN BIOPHARMA HOLDING AB
    Inventors: Ann-Mari Svennerholm, Joshua Tobias, Nils Carlin, Jan Holmgren
  • Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
    Patent number: 10414806
    Abstract: A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETC. Cells and vaccines obtainable by the above methods.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: September 17, 2019
    Assignee: Scandinavian Biopharma Holding AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias
  • Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
    Patent number: 9790257
    Abstract: A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETC. Cells and vaccines obtainable by the above methods.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: October 17, 2017
    Assignee: Scandinavian Biopharma Holding AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias
  • Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
    Patent number: 9273103
    Abstract: A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: March 1, 2016
    Assignee: Scandinavian Biopharma Holding AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias
  • METHOD FOR INCREASING ETEC CS6 ANTIGEN PRESENTATION ON CELL SURFACE AND PRODUCTS OBTAINABLE THEREOF
    Publication number: 20140178436
    Abstract: A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
    Type: Application
    Filed: September 10, 2012
    Publication date: June 26, 2014
    Applicant: SCANDINAVIAN BIOPHARMA HOLDING AB
    Inventors: Nils Carlin, Ann-Mari Svennerholm, Joshua Tobias