Patents Assigned to SCIENOVA GMBH
  • Patent number: 11896975
    Abstract: The invention having functional vertical disposable reaction systems having a vertically mounted semipermeable membrane for sample preparation, chemical reactions, dialysis, enzymatic/microbiological fermentation, multistage processes, in vitro protein biosynthesis on a laboratory scale, formed from a base body and an exchangeable lid having different functions. For exchange across the membrane, the system is placed vertically into an outer volume consisting of gas, liquid or solid constituents. The system consists of a dimensionally stable base body and a liquid-tight lid having a functional support going toward the base of the base body, the dimensionally stable base body forming at least one noncapillary reaction space as inner volume with at least one semipermeable membrane as lateral wall. The high flexibility in use results from the combination of variants of the base bodies with different lid variants for different areas of use.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: February 13, 2024
    Assignee: Scienova GmbH
    Inventors: Stefan Kreusch, Thomas Richter, Raffael Rubick
  • Patent number: 10272433
    Abstract: A reaction vessel for a vertical operating position geometrically bits into a standard receiving vessel providing an outer volume, for example a centrifuge tube, microplates and deep well plates. The reaction vessel including at least one upper opening with a seal element for reversible sealing for typical liquid handling techniques for filling, emptying mixing and gassing; at least one upper opening for pressure balancing and overrun; and a form stable body which forms at least one non capillary reaction cavity as an inner volume with at least one semipermeable membrane as a side wall. The at least one upper opening with the seal element for reversible sealing for standard liquid handling for filling, emptying, mixing and gassing leads through at least one capillary channel in the form stable body vertically into a lower portion of the reaction vessel and forms an opening at this location.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: April 30, 2019
    Assignee: Scienova GmbH
    Inventors: Stefan Kreusch, Raffael Rubick, Claudia Macha
  • Patent number: 8758706
    Abstract: A device is provided by means of which biomolecules in samples in a volume range from <1 ?l to 500 ?l can be received, treated and stored in a quick, reproducible and loss-free manner as easily, effortlessly and practically as possible, and without any risk of damaging the device. The device includes sample vessels that are configured, in terms of size and shape, as dimensionally and positionally stable capillaries that are open at both ends, the longitudinal walls of which are completely or partially made of a semi-permeable membrane.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: June 24, 2014
    Assignee: SCIENOVA GmbH
    Inventors: Heidrun Rhode, Stefan Kreusch, Helga Endmann, Michael Händel, Günther Sammler, Edith Zimmermann
  • Publication number: 20110163023
    Abstract: The invention relates to a device for the equilibrium dialysis of fluids having small volumes. The object of the invention of creating a device for equilibrium dialysis , the device being designed as a simple as possible, being universally usable and reliable in the use thereof, with which a large ratio of the membrane surface to the sample volume is created and which facilitates very short diffusion paths inside the sample as well as low sample losses, even with small sample volumes, is achieved in that a device is proposed, which comprises corresponding capillaries (1, 1?), which are connected through a membrane (2) and each are open at the ends on both sides, said capillaries for dialysis purposes each comprising a preferably substantially U-shaped arched capillary portion, and the at least one opening (4, 4?) thereof being provided each with a sealing element for introducing and/or removing the liquid.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 7, 2011
    Applicant: SCIENOVA GMBH
    Inventors: Stefan Kreusch, Robert Fleischhauer, Maximilian Bauer, Carlotta Werner