Abstract: The invention provides an apparatus and methods for depositing materials on a substrate, and for performing other selected functions, such as material destruction and removal, temperature control, imaging, detection, therapy and positional and locational control. In various embodiments, the apparatus and methods are suitable for use in a tabletop setting, in vitro or in vivo.
Type:
Grant
Filed:
July 15, 2004
Date of Patent:
December 28, 2010
Assignee:
Sciperio, Inc.
Inventors:
William L. Warren, Robert L. Parkhill, Robert L. Stewart, Anatoly M. Kachurin, Robert M. Taylor, Kenneth H. Church
Abstract: Detection of a rarely occurring event within one or more biological samples includes (a) processing each biological sample to provide a gellable liquid solution comprising concentrated biological sample and a flourochrome designed to associate with a rarely occurring event within the concentrated biological sample; (b) depositing the solution in a layer on a surface of a slide; and (c) scanning the solution on the slide with energy adapted to cause fluorescence of the flourochrome to detect potential instances of the rarely occurring event within the concentrated biological sample in the solution.
Type:
Grant
Filed:
February 8, 2007
Date of Patent:
September 29, 2009
Assignee:
Sciperio, Inc.
Inventors:
Vladimir M. Pelekhaty, Anatoliy Kachurin, William Warren, Kenneth Church, Heather Fahlenkamp, Russell Higbee
Abstract: An optimal configuration for at least one antenna and/or at least one frequency selective surface is generated. A configuration of elements is generated by selecting a simple configuration of at least one element and applying a genetic algorithm to the simple configuration to generate a configuration optimized for various characteristics. A stochastic process may be used to randomly select an arrangement of elements as the simple antenna configuration and to select elements that connect the randomly selected elements to produce a stochastic configuration to which the genetic algorithm is then applied. Alternatively, an iterated or semi-iterated process may be applied to the simple antenna configuration to produce a fractal or a semi-fractal configuration, respectively, to which the genetic algorithm is then applied. Also, the elements may be optimized independently.
Type:
Grant
Filed:
February 8, 2002
Date of Patent:
April 29, 2008
Assignee:
Sciperio, Inc.
Inventors:
Douglas H. Werner, Pingjuan L. Werner, Kenneth H. Church, Michael John Wilhelm
Abstract: A micro-helix antenna. The antenna comprises a helically-shaped conductive element disposed on a dielectric core. The diameter of the helix formed by the conductive element is very small relative to the wavelength of the antenna, preferably no more than about 1/100th of the wavelength. Having such a small diameter, this micro-helix antenna can be further compressed into two- and three-dimensional shapes, such as spirals, helices and meandering or stochastic patterns. The micro-helix antenna can be created by pressing a fine wire into a helical shape. Alternately, the helical conductor can be formed by a laser ablation process or laying down the helical shape using a direct-write process.
Type:
Grant
Filed:
June 1, 2005
Date of Patent:
February 27, 2007
Assignee:
Sciperio, Inc.
Inventors:
Michael J. Wilhelm, Robert M. Taylor, Ryan T. Salisbury
Abstract: The invention provides an apparatus and methods for depositing materials on a substrate, and for performing other selected functions, such as material destruction and removal, temperature control, imaging, detection, therapy and positional and locational control. In various embodiments, the apparatus and methods are suitable for use in a tabletop setting, in vitro or in vivo.
Type:
Grant
Filed:
August 23, 2002
Date of Patent:
January 17, 2006
Assignee:
Sciperio, Inc.
Inventors:
William L. Warren, Robert L. Parkhill, Robert L. Stewart, Anatoly M. Kachurin, Robert M. Taylor, Brian K. Hargrave, Kenneth H. Church, Michael N. Nguyen, Mark L. Kargel, Mark W. Simpkins
Abstract: Sample preparation apparatus and method includes a wafer stage platform with an optical microscope and integrated pattern recognition to automatically address specific locations on the wafer sample of interest. A laser attaches to the optical microscope to mill a set pattern around the area of interest. A precision micro-manipulator engages the sample support structure, extracts the structure, and places the structure in a TEM holder or holder tip. The holder or holder tip can then be placed inside a FIB for final thinning, followed by direct transfer into the TEM.
Type:
Grant
Filed:
August 3, 2001
Date of Patent:
January 11, 2005
Assignees:
Ascend Instruments, Inc., Sciperio, Inc.
Abstract: Concentration of a solute in a solution is determined. Light from a light source is received at a chamber containing the solute and the solution. The light is transmitted along an optical path length of the chamber, through the solute and the solution, and output from the chamber. The light output from the chamber is detected by a detector. The optical path length of the chamber is selected to optimize sensitivity of the detector. The concentration of the solute in the solution is determined based on the light received by the detector.
Type:
Grant
Filed:
May 30, 2002
Date of Patent:
December 14, 2004
Assignee:
Sciperio, Inc.
Inventors:
Christopher S. Cassidy, Kenneth H. Church, William Ardrey, Keith Teague
Abstract: Paste compositions for forming ceramic composites can include at least one solvent; at least one optional binder; at least one low-temperature frit glass; and a plurality of one or more functional particles; wherein the paste is capable of forming a composite upon low-temperature processing or laser processing.
Type:
Grant
Filed:
December 17, 2001
Date of Patent:
September 21, 2004
Assignees:
Sciperio, Inc., Oklahoma State University
Abstract: The present invention relates to a method for producing a low temperature 0-3 composite material, comprising the steps of providing a mixture, wherein the mixture comprises a liquid phase and a particulate phase and wherein the liquid phase comprises a reactive metal alkoxide; depositing the mixture on to a plastic substrate; and consolidating the mixture to provide a 0-3 composite material, wherein the 0-3 composite material is suitable for use as an electronic component.
Type:
Grant
Filed:
February 7, 2001
Date of Patent:
December 16, 2003
Assignee:
Sciperio, Inc.
Inventors:
Robert L. Parkhill, Steven M. Coleman, Edward T. Knobbe
Abstract: A compact integrated biosensor has an integrated light source and integrated optical detectors made with gratings, dielectric coating, or prism for specific wavelength selection to define signatures that identify elements, biohazardous materials, environmentally hazardous materials, biological substance or any chemical substance on the sample holders. A micropump draws gas, ambient fluids and samples to the sample holders. Electrical signals are provided from the optical detectors on output lines to the microprocessor. A device connected to the microprocessor compares characteristic responses to actual signal parameters. An output indicates the presence (or absence) of particular biological, chemical or environmentally hazardous material. A battery, fuel cell or solar cell operated power supply provides electrical energy to the integrated light source and optical detectors.