Patents Assigned to Scotgen Biopharmaceuticals Incorporated
  • DNA encoding antibodies with altered effector functions
    Patent number: 5648260
    Abstract: The DNA encoding an antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the Cl component of complement is produced by replacing the nucleic acid encoding at least one amino acid residue in the constant portion of the antibody with nucleic acid encoding a different residue.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 15, 1997
    Assignee: Scotgen Biopharmaceuticals Incorporated
    Inventors: Gregory Paul Winter, Alexander Robert Duncan, Dennis Raymond Burton
  • Antibodies with altered effector functions
    Patent number: 5624821
    Abstract: An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 29, 1997
    Assignee: Scotgen Biopharmaceuticals Incorporated
    Inventors: Gregory P. Winter, Alexander R. Duncan, Dennis R. Burton