Patents Assigned to Second Sight Medical Products, Inc.
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Patent number: 10292579Abstract: The invention is a method of automatically adjusting a retinal electrode array to the neural characteristics of an individual patient. By recording electrically evoked electroretinograms (eERG) to a predetermined input stimulus, one can alter that input stimulus to the needs of an individual patient. A minimum input stimulus is applied to a patient, followed by recording the eERG response to the input stimulus. By gradually increasing stimulus levels, one can determine the minimum input that creates a neural response, thereby identifying the threshold stimulation level. One can further determine a maximum level by increasing stimulus until a predetermined maximum neural response is obtained. However, eERG signals include a significant amount of noise. Applicants have developed novel techniques for artifact reduction and noise filtering to provide an accurate measure of neural activity.Type: GrantFiled: December 5, 2011Date of Patent: May 21, 2019Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Gislin Dagnelie, Hendrik Christiaan Stronks
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Patent number: 10220202Abstract: A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on the polymer base layer and the metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.Type: GrantFiled: May 2, 2017Date of Patent: March 5, 2019Assignee: Second Sight Medical Products, Inc.Inventors: Jordan Neysmith, Robert Greenberg, James Little, Brian Mech, Neil Talbot, Qingfang Yao, David Zhou
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Patent number: 10201697Abstract: The disclosure relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and at least one support embedded in said array. The disclosure further relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a folded flexible circuit cable connecting the electrode array with an interconnection pad.Type: GrantFiled: November 27, 2017Date of Patent: February 12, 2019Assignee: Second Sight Medical Products, Inc.Inventors: Robert J Greenberg, Eugene de Juan, Mark S Humayun, Kelly McClure, Neil Hamilton Talbot, Jordan Matthew Neysmith, Brian V Mech, James Singleton Little, Mohamed Khaldi
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Patent number: 10188853Abstract: The present invention is a flexible circuit electrode array with a polymer base layer, metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue, a polymer top layer deposited on the polymer base layer and the metal traces, and a soft polymer filling a void through both the polymer base layer and polymer top layer, the soft polymer forming drum stress relief around an attachment point.Type: GrantFiled: March 7, 2008Date of Patent: January 29, 2019Assignee: Second Sight Medical Products, Inc.Inventors: Rajat Agrawal, Robert J. Greenberg, Mark S. Humayun, James Singleton Little, Brian V. Mech, Jordan Matthew Neysmith, Neil Hamilton Talbot, Dao Min Zhou
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Patent number: 10159845Abstract: The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package that is suitable for implantation in living tissue, for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.Type: GrantFiled: November 13, 2015Date of Patent: December 25, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Alfred E. Mann, Dao Min Zhou, Neil Talbot, Jerry Ok, Gailland R. Nolan
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Patent number: 10159832Abstract: The present invention provides an implantable electrode with increased stability wherein the surface is of the electrode comprises mesh grids which are filled with sticks which are filed with a conducting or insulating material. The present invention further provides a method of manufacturing an electrode with increased stability, comprising: depositing a metal layer on an base layer; applying photoresist layer on the metal layer; patterning the photoresist layer providing openings; electroplating the openings with metal; removing the photoresist layer leaving spaces; and filling the spaces with polymer.Type: GrantFiled: October 26, 2007Date of Patent: December 25, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Dao Min Zhou, Jerry Ok, Neil Hamilton Talbot, Brian V. Mech, James Singleton Little, Robert J. Greenberg
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Publication number: 20180345019Abstract: The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to the at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain. Variations of the embodiments depend on the physical locations of the coil(s), package(s) and array(s) with respect to the head, cranium, dura, and brain.Type: ApplicationFiled: July 24, 2018Publication date: December 6, 2018Applicant: SECOND SIGHT MEDICAL PRODUCTS, INC.Inventors: Robert J. Greenberg, David Daomin Zhou, Brian V. Mach, Neil Hamilton Talbot, Rongqing Dai, Richard Agustin Castro, Kelly H. McClure
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Patent number: 10137303Abstract: The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to the at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The device is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals. The output signals provide control for a motor prosthesis and the inputs signals provide sensory feedback for the motor prosthesis. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.Type: GrantFiled: May 16, 2012Date of Patent: November 27, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J Greenberg, David Daomin Zhou, Brian V Mech, Neil Hamilton Talbot, Rongqing Dai, Richard Agustin Castro, Kelly H. McClure
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Patent number: 10105263Abstract: A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit.Type: GrantFiled: December 7, 2012Date of Patent: October 23, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert Greenberg, Kelly H McClure, Arup Roy
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Patent number: 10105532Abstract: Electrode arrays for biological implants are disclosed. Electrodes are arranged in such a way so that electrical traces overlap other electrical traces in a separate layer without X shaped crossing, while overlapping to a degree sufficient to prevent dielectric breakdown of the insulating, separating layer.Type: GrantFiled: February 5, 2018Date of Patent: October 23, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Neil H Talbot, Jordan M Neysmith, Dustin Tobey
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Publication number: 20180256307Abstract: Novel multilayer composite material vias for biological implants are disclosed. The vias comprise two metals, so that the metal more compatible with biological environments is on one end of the via, and the metal more compatible with fabrication of a hermetic package is on the other end of the via.Type: ApplicationFiled: May 14, 2018Publication date: September 13, 2018Applicant: Second Sight Medical Products, Inc.Inventors: Jerry Ok, Alfred E. Mann
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Patent number: 10065036Abstract: The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.Type: GrantFiled: September 28, 2007Date of Patent: September 4, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Amy Chu Peishuan Hines, Dao Min Zhou, Arup Roy, Rongqing Dai, Robert J. Greenberg
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Publication number: 20180243561Abstract: The present invention is an improved visual prosthesis including a video processing unit with user controls optimized for use by blind individuals. The controls include easily identifiable shapes. The controls are programmable to provide improved usability with a simple tactile interface.Type: ApplicationFiled: April 30, 2018Publication date: August 30, 2018Applicant: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Arup Roy
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Patent number: 10052482Abstract: The present invention is an improved spatial fitting and training system for a visual prosthesis. The system of the present invention maps projected locations of percepts, where a person perceives a percept from a visual prosthesis to the intended location of the percepts. The projected location may vary over time. These test results can be used to correct a visual prosthesis or spatially map the visual prosthesis.Type: GrantFiled: October 20, 2017Date of Patent: August 21, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Michael Barry, Gislin Dagnelie
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Patent number: 10052478Abstract: The present invention consists of an implantable device with at least one package that houses electronics that receives input data or signals, and optionally, power, from an external system through at least one coil attached to the at least one package, processes the input data and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that is/are attached to the at least one package. The invention, or components thereof, is/are intended to be installed in the head, or on or in the cranium, or on the dura, or on or in the brain.Type: GrantFiled: March 13, 2017Date of Patent: August 21, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J Greenberg, Brian V Mech, Kelly H McClure
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Patent number: 10055827Abstract: Digital image filters and related methods for image contrast enhancement are disclosed. According to one aspect of the method, an invariant brightness level is initially determined. For each pixel of an input image, the invariant brightness level is subtracted from the input brightness of the pixel. The resulting value is multiplied with a contrast adjustment constant. After that, the invariant brightness level is added. Further aspects of the method can involve histogram equalization.Type: GrantFiled: September 16, 2009Date of Patent: August 21, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Chunhong Zhou, Arup Roy, Kelly H. McClure
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Patent number: 10052481Abstract: A visual prosthesis apparatus and a method for providing artificial vision are disclosed in the present disclosure. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured stimulate neural tissue in a subjects eye based on the stimulation patterns. An artificial vision may be provided by capturing a video image, converting the video image to stimulation patterns, and stimulating neural tissue in a subjects eye based on the stimulation patterns.Type: GrantFiled: October 28, 2007Date of Patent: August 21, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Kelly H. McClure, Arup Roy, Sumit Yadav, Richard Agustin Castro, Susan McCord
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Patent number: 10016590Abstract: The present invention provides a flexible circuit electrode array adapted for neural stimulation, comprising: a polymer base layer; metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on the polymer base layer and the metal traces at least one tack opening. The present invention provides further a method of making a flexible circuit electrode array comprising depositing a polymer base layer; depositing metal on the polymer base layer; patterning the metal to form metal traces; depositing a polymer top layer on the polymer base layer and the metal traces; and preparing at least one tack opening.Type: GrantFiled: March 31, 2017Date of Patent: July 10, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J Greenberg, Jordan M Neysmith, James S Little, Brian V Mech, Neil H Talbot
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Patent number: 10010396Abstract: Novel multilayer composite material vias for biological implants are disclosed. The vias comprise two metals, so that the metal more compatible with biological environments is on one end of the via, and the metal more compatible with fabrication of a hermetic package is on the other end of the via.Type: GrantFiled: March 19, 2014Date of Patent: July 3, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Jerry Ok, Alfred E Mann
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Publication number: 20180178002Abstract: The disclosure relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and at least one support embedded in said array. The disclosure further relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a folded flexible circuit cable connecting the electrode array with an interconnection pad.Type: ApplicationFiled: November 27, 2017Publication date: June 28, 2018Applicant: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Eugene de Juan, Mark S Humayun, Kelly McClure, Neil Hamilton Talbot, Jordan Matthew Neysmith, Brian V Mech, James Singleton Little, Mohamed Khaldi