Patents Assigned to SENTINELLA PHARMACEUTICALS ,INC.
  • Lantibiotic NAI-802, Pharmaceutically Acceptable Salts, Compositions and Uses Thereof
    Publication number: 20140094402
    Abstract: The present invention concerns novel lantibiotic compounds, processes for the isolation and preparation thereof, pharmaceutical compositions containing the same, pharmaceutical acceptable salts thereof, and methods of use of the lantibiotics as antibacterial agents.
    Type: Application
    Filed: March 30, 2012
    Publication date: April 3, 2014
    Applicant: SENTINELLA PHARMACEUTICALS, INC.
    Inventors: Sonia Ilaria Maffioli, Matteo Simone, Paolo Monciardini, Eleonora Gaspari
  • Genes and Proteins for the Biosynthesis of the Lantibiotic 107891
    Publication number: 20140038297
    Abstract: The Invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 6, 2014
    Applicant: Sentinella Pharmaceuticals, Inc.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mecorillo
  • Genes and proteins for the biosynthesis of the lantibiotic 107891
    Patent number: 8609367
    Abstract: The invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: December 17, 2013
    Assignee: Sentinella Pharmaceuticals, Inc.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mercorillo
  • Lantibiotic Carboxyamide Derivatives With Enhanced Antibacterial Activity
    Publication number: 20120053115
    Abstract: The present invention relates to novel amide derivatives of the lantibiotic 97518 and their uses. In particular, the present invention describes novel compounds having general formula (II) and their use as antibiotic.
    Type: Application
    Filed: November 24, 2008
    Publication date: March 1, 2012
    Applicant: Sentinella Pharmaceuticals, Inc.
    Inventors: Sonia Ilaria Maffioli, Cristina Brunati, Donatella Potenza, Francesca Vasile, Stefano Donadio
  • GENES AND PROTEINS FOR THE BIOSYNTHESIS OF THE LANTIBIOTIC 107891
    Publication number: 20120015418
    Abstract: The invention relates to the field of lantibiotics, and more specifically to the isolation of nucleic acid molecules that code for the enzymes required for the biosynthetic pathway of the lantibiotic 107891 and the homologues thereof.
    Type: Application
    Filed: August 3, 2007
    Publication date: January 19, 2012
    Applicant: SENTINELLA PHARMACEUTICALS ,INC.
    Inventors: Stefano Donadio, Margherita Sosio, Stefania Serina, Davide Mercorillo