Abstract: The instant invention provides materials and methods for producing immunologically active antigens derived from members of the Picornaviridae virus family. The picornavirus antigens of the invention may be in a form for use as a vaccine administered to a subject in a therapeutic treatment or for the prevention of a picornavirus infection. The picornavirus antigens of the invention may be in the form of an immunogenic composition for use in vaccines which are administered for the prevention of an Enterovirus infection. The instant invention further encompasses immunogenic compositions comprising Human enterovirus A, Human enterovirus B, Human enterovirus C, Human enterovirus D antigens and their use in vaccines for the prevention of an Enterovirus infection.
Type:
Grant
Filed:
April 27, 2018
Date of Patent:
February 11, 2020
Assignee:
SENTINEXT THERAPEUTICS Sdn Bhd
Inventors:
Mary Jane Cardosa, Mohamad Fakruddin Jamiluddin, Sharifah Binti Hamid
Abstract: The instant invention provides materials and methods for producing immunologically active antigens derived from members of the Picornaviridae virus family. The picornavirus antigens of the invention may be in a form for use as a vaccine administered to a subject in a therapeutic treatment or for the prevention of a picornavirus infection. The picornavirus antigens of the invention may be in the form of an immunogenic composition for use in vaccines which are administered for the prevention of an Enterovirus infection. The instant invention further encompasses immunogenic compositions comprising Human enterovirus A, Human enterovirus B, Human enterovirus C, Human enterovirus D antigens and their use in vaccines for the prevention of an Enterovirus infection.
Type:
Grant
Filed:
April 27, 2018
Date of Patent:
February 4, 2020
Assignee:
SENTINEXT THERAPEUTICS Sdn Bhd
Inventors:
Mary Jane Cardosa, Mohamad Fakruddin Jamiluddin, Sharifah Binti Hamid
Abstract: The instant invention provides materials and methods for producing immunologically active antigens derived from members of the Picornaviridae virus family. The picornavirus antigens of the invention may be in a form for use as a vaccine administered to a subject in a therapeutic treatment or for the prevention of a picornavirus infection. The picornavirus antigens of the invention may be in the form of an immunogenic composition for use in vaccines which are administered for the prevention of an Enterovirus infection. The instant invention further encompasses immunogenic compositions comprising Human enterovirus A, Human Enterovirus B, Human enterovirus C, Human Enterovirus D antigens and their use in vaccines for the prevention of an enterovirus infection.
Type:
Grant
Filed:
November 1, 2012
Date of Patent:
June 5, 2018
Assignee:
SENTINEXT THERAPEUTICS Sdn Bhd
Inventors:
Mary Jane Cardosa, Mohamad Fakruddin Jamiluddin, Sharifah Binti Hamid
Abstract: The instant invention provides materials and methods for producing immunologically active antigens derived from members of the Picornaviridae virus family. The picornavirus antigens of the invention may be in a form for use as a vaccine administered to a subject in a therapeutic treatment or for the prevention of a picornavirus infection. The picornavirus antigens of the invention may be in the form of an immunogenic composition for use in vaccines which are administered for the prevention of an Enterovirus infection. The instant invention further encompasses immunogenic compositions comprising Human enterovirus A, Human enterovirus B, Human enterovirus C, Human enterovirus D antigens and their use in vaccines for the prevention of an Enterovirus infection.
Type:
Application
Filed:
August 20, 2014
Publication date:
February 26, 2015
Applicant:
SENTINEXT THERAPEUTICS SDN BHD
Inventors:
Mary Jane Cardosa, Mohamad Fakruddin Jamiluddin, Sharifah Binti Hamid